Patents by Inventor Hao Guo

Hao Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220054561
    Abstract: Disclosed herein are data indicating that specific gut commensal bacteria, and metabolites thereof, can mitigate the outcome of high dose total body irradiation. Based on this, provided herein are methods of mitigating and/or preventing side effects from radiation therapy using short chain fatty acid producing bacterium or metabolites thereof. Cancer and tumor treatments and adjuvant therapies are also provided. Methods of treating and/or mitigating damage to a hematopoietic and/or gastrointestinal system in a subject are also provided using the disclosed adjuvant therapeutic compositions.
    Type: Application
    Filed: December 16, 2019
    Publication date: February 24, 2022
    Inventors: Jenny P.-Y. Ting, Hao Guo, Liang Chen, Jason W. Tam, Vincent B. Young, Mark Koenigsknecht
  • Publication number: 20210378569
    Abstract: The present disclosure provides a cuboid magnetometer with high fluorescence collection efficiency, used for cardiac magnetic field measurement, and based on nitrogen-vacancy (NV) centers in diamond, and a cardiac magnetic field measurement system. The cardiac magnetic field measurement system includes a magnetic shielding chamber, a non-magnetic bed, an array probe for cardiac magnetic field measurement, a three-axis displacement platform, a high-speed data collection card, a fiber laser source, a microwave source, and a computer. The array probe for cardiac magnetic field measurement includes a non-magnetic shell, a stepping motor, a porous rotary fiber coupling apparatus, a fiber bundle set, a special photodetector (PD) set, a filter set, a ring-shaped antenna, and special diamond.
    Type: Application
    Filed: May 22, 2021
    Publication date: December 9, 2021
    Inventors: Zongmin MA, Jun LIU, Li QIN, Xiaoming ZHANG, Doudou ZHENG, Yunbo SHI, Jun TANG, Hao GUO, Xiaocheng WANG
  • Patent number: 11124559
    Abstract: Described herein is the use of elastin-like polypeptides to generate hemoglobin-based oxygen carriers as a means of preventing and treating conditions caused by blood loss or anemia, for example, hemorrhagic shock. Elastin-like polypeptides are capable of creating therapeutically functional fusion proteins through genetic engineering with a therapeutic agent, for example, hemoglobin and biologic equivalent thereof. Specific forms of these fusion proteins have the ability to form into spherical nanoparticles possessing a therapeutically agent at their core. This provides a unique basis for employing elastin-like polypeptides as hemoglobin carriers in the manufacture of blood substitutes.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: September 21, 2021
    Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Jordan Tremaine Despanie, Hao Guo, John Andrew MacKay
  • Publication number: 20210252700
    Abstract: The present disclosure relates to a visual servoing method based on fusion of distance space and image feature space. The method includes: constructing an image Jacobian matrix; constructing a depth Jacobian matrix; fusing the image Jacobian matrix and the depth Jacobian matrix, to obtain a hybrid visual servoing Jacobian matrix; and obtaining a robot motion control amount according to the hybrid visual servoing Jacobian matrix by using a control algorithm, to enable a robot to move to a target position, to complete precise positioning.
    Type: Application
    Filed: January 15, 2021
    Publication date: August 19, 2021
    Inventors: Huijun GAO, Weiyang LIN, Chenlu LIU, Hao GUO, Xinghu YU, Mingsi TONG
  • Publication number: 20210257124
    Abstract: A flexible electrode and a fabrication method therefor are provided. The flexible electrode is formed by mixing organic-soft-matrix with inorganic-hard-material. The inorganic-hard-material is composed of silicate lamellar blocks and electrochemically active materials. Each of the silicate lamellar blocks is formed by multiple stacked nano-scaled sheet-like silicate lamellae. The organic-soft-matrix includes conductive polymer and binder. The binder is water-soluble and ionically conductive. The flexible electrode has a floor-ramp like opened-perforated layer structure formed by hierarchically aggregated inorganic silicate lamellar blocks, and pores of the opened-perforated layer structure are filled with the organic-soft-matrix, so as to form a network channel structure having organic phase and inorganic phase interlaced with each other.
    Type: Application
    Filed: February 2, 2021
    Publication date: August 19, 2021
    Applicant: National Synchrotron Radiation Research Center
    Inventors: Wei-Tsung Chuang, Rong-Hao Guo, Ming-Jay Deng
  • Patent number: 11095189
    Abstract: A driving mechanism is provided. The driving mechanism connects with a frame and a driving wheel by two ends thereof. The driving mechanism includes a motor housing, a motor assembly and a driving controller. The motor housing supports the frame and defines an inner space. The motor assembly is detachably assembled with the motor housing and located in the inner space. The motor assembly drives the driving wheel. The driving controller is detachably assembled with the motor housing, located in the inner space, and electrically connected with the motor assembly.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: August 17, 2021
    Assignee: DELTA ELECTRONICS, INC.
    Inventors: Wu-Chen Lin, Chi-Hsiang Kuo, Chien-Chung Shih, Chia-Hsiang Yang, Yi-Yu Lee, Siao-Hao Guo
  • Publication number: 20210230359
    Abstract: The present disclosure relates to synthesis of porous polymer networks and applications of such materials. The present disclosure relates to a method of fabricating of a porous polymer network comprising: (a) providing: (i) a first reactant comprising a plurality of compounds comprising at least one acetyl group, said plurality of compounds comprising at least one compound type, and (ii) a second reactant comprising an alkylsulfonic acid, and (b) creating a solution of said reactants, (c) casting said solution in a form, and (d) treating said solution under such conditions so as to produce a porous polymer network.
    Type: Application
    Filed: January 28, 2021
    Publication date: July 29, 2021
    Inventors: Lei Fang, Zi-Hao Guo, Chenxu Wang, Qiang Zhang, Hong-Cai Zhou
  • Publication number: 20210141926
    Abstract: In one embodiment, a method includes accessing a first machine-learning model trained to generate a feature representation of an input data, a second machine-learning model trained to generate a desired result based on the feature representation, and a third machine-learning model trained to generate an undesired result based on the feature representation, and training a fourth machine-learning model by generating a secured feature representation by processing a first output of the first machine-learning model using the fourth machine-learning model, generating a second output and a third output by processing the secured feature representation using, respectively, the second and third machine-learning models, and updating the fourth machine-learning model according to an optimization function configured to optimize a correctness of the second output and an incorrectness of the third output.
    Type: Application
    Filed: February 13, 2020
    Publication date: May 13, 2021
    Inventors: Cristian Canton Ferrer, Brian Dolhansky, Hao Guo, Eric Erkon Hsin, Phong Dinh
  • Publication number: 20210106620
    Abstract: Disclosed is a method for promoting immune cell proliferation. The method comprises the following step: upregulating the expression of low-density lipoprotein receptor-related proteins or fragments thereof in immune cells.
    Type: Application
    Filed: March 25, 2019
    Publication date: April 15, 2021
    Applicant: ORIGINCELL THERAPEUTICS CO., LTD.
    Inventors: Youguo LING, Hao GUO, Haili MA, Huijiao LI, Huajing WANG, Bi YING, Huanfeng YANG, Xiaowen HE
  • Publication number: 20210081695
    Abstract: The present application discloses an image processing method, apparatus, electronic device and computer readable storage medium. The image processing method comprises detecting a text region in an image to be processed, recognizing the text region to obtain a text recognition result. In this application, the text recognition in the image to be processed is realized, the recognition manner for the text in the image is simplified, and the recognition effect for the text is improved.
    Type: Application
    Filed: December 3, 2019
    Publication date: March 18, 2021
    Inventors: Xiaobing WANG, Yingying JIANG, Xiangyu ZHU, Hao GUO, Yi YU, Pingjun LI, Zhenbo LUO
  • Patent number: 10934389
    Abstract: The present disclosure relates to synthesis of porous polymer networks and applications of such materials. The present disclosure relates to a method of fabricating of a porous polymer network comprising: (a) providing: (i) a first reactant comprising a plurality of compounds comprising at least one acetyl group, said plurality of compounds comprising at least one compound type, and (ii) a second reactant comprising an alkylsulfonic acid, and (b) creating a solution of said reactants, (c) casting said solution in a form, and (d) treating said solution under such conditions so as to produce a porous polymer network.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: March 2, 2021
    Assignee: The Texas A&M University System
    Inventors: Lei Fang, Zi-Hao Guo, Chenxu Wang, Qiang Zhang, Hong-Cai Zhou
  • Patent number: 10900713
    Abstract: A low-temperature quick-freezing freeze-drying system provided by the invention includes: a compressor unit, a first heat exchanger, an air cooler, a second heat exchanger, a throttling element, a third heat exchanger, a circulating fan, a drying chamber, a third valve, a fourth valve and connecting pipelines, and the above elements form a refrigeration circulation loop, a quick freezing/freeze-drying circulation loop, and a desorption drying circulation loop, thereby realizing the low-temperature quick-freezing and freeze-drying of materials. The invention adopts the heat exchangers with a cold storage function, so that the refrigeration capacity of the compressor is stored and used intensively to achieve rapid cooling of the materials.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: January 26, 2021
    Assignee: TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY, CHINESE ACADEMY OF SCIENCES
    Inventors: Maoqiong Gong, Yanxing Zhao, Hao Guo, Jun Shen, Xueqiang Dong
  • Publication number: 20200347724
    Abstract: A microorganism curing anti-seepage device based on capsule transmission and control includes a stock bin which includes a mixing bin and an oil storage bin separated from the mixing bin. A feed pipe and an oil injection pipe are provided on the stock bin. A central shaft is rotatably provided within the mixing bin. A stirring component is provided on the central shaft. A delivery pipe is provided at a bottom portion of the mixing bin, an oil conduit is provided at a bottom portion of the oil storage bin, a jet pipe is provided at a junction of the oil conduit and the delivery pipe. Since microbial capsules are decomposed layer by layer, after the microbial capsules reach fissures, the microbial bacteria, the nutrient solution and the curing liquid are released step by step, and then calcium carbonate is induced by microorganisms to achieve solidification and anti-seepage of fissures.
    Type: Application
    Filed: July 22, 2020
    Publication date: November 5, 2020
    Inventors: Liang Guo, Xiaoyu He, Junwei Zhang, Mingwei Liao, Hao Guo, Latie Abu, Chun Pei, Ziwei Xiao, Yiqi Peng
  • Publication number: 20200332244
    Abstract: The present invention discloses a piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism. The device includes: a cover, a flexible hinge mechanism, a base, a screw cap and an end cap fixedly assembled together, the base being provided with a pump interface; and a micropipette fixedly mounted in the base, the screw cap and the end cap and extending outward, the micropipette being in communication with the pump interface; wherein the flexible hinge mechanism comprises a housing, a piezoelectric ceramic package module encapsulated in the housing, a central shaft fixedly mounted with the piezoelectric ceramic package module and the base, and a vibration output shaft extending from the piezoelectric ceramic package module into the central shaft, a plurality of flexible hinge beams being disposed between the central shaft and the housing.
    Type: Application
    Filed: May 22, 2018
    Publication date: October 22, 2020
    Inventors: Haibo HUANG, Xiwei GAO, Liguo CHEN, Fei ZHOU, Hao GUO, Lingfeng CHANG, Jizhu LIU, Yangjun WANG, Lining SUN
  • Publication number: 20200282006
    Abstract: Provided herein are methods of mitigating and/or preventing side effects from chemotherapy and/or radiotherapy in a subject by administering a therapeutically effective amount of a toll-like receptor 2/6 (TLR 2/6) ligand, including fibroblast-stimulating lipopeptide 1 (FSL-1). Methods of treating and/or preventing gastrointestinal disorders are also disclosed. Additionally, methods of increasing granulocyte colony-stimulating factor (G-CSF) production in a subject undergoing a medical treatment, including administering FSL-1 compositions, are provided.
    Type: Application
    Filed: November 19, 2018
    Publication date: September 10, 2020
    Inventors: Jenny P.-Y. Ting, Willie June Brickey, Hao Guo, Cathryn Julia Robbins
  • Publication number: 20200212759
    Abstract: A driving mechanism is provided. The driving mechanism connects with a frame and a driving wheel by two ends thereof. The driving mechanism includes a motor housing, a motor assembly and a driving controller. The motor housing supports the frame and defines an inner space. The motor assembly is detachably assembled with the motor housing and located in the inner space. The motor assembly drives the driving wheel. The driving controller is detachably assembled with the motor housing, located in the inner space, and electrically connected with the motor assembly.
    Type: Application
    Filed: May 17, 2019
    Publication date: July 2, 2020
    Inventors: Wu-Chen Lin, Chi-Hsiang Kuo, Chien-Chung Shih, Chia-Hsiang Yang, Yi-Yu Lee, Siao-Hao Guo
  • Publication number: 20200148812
    Abstract: The present disclosure relates to synthesis of porous polymer networks and applications of such materials. The present disclosure relates to a method of fabricating of a porous polymer network comprising: (a) providing: (i) a first reactant comprising a plurality of compounds comprising at least one acetyl group, said plurality of compounds comprising at least one compound type, and (ii) a second reactant comprising an alkylsulfonic acid, and (b) creating a solution of said reactants, (c) casting said solution in a form, and (d) treating said solution under such conditions so as to produce a porous polymer network.
    Type: Application
    Filed: January 16, 2020
    Publication date: May 14, 2020
    Inventors: Lei Fang, Zi-Hao Guo, Chenxu Wang, Qiang Zhang, Hong-Cai Zhou
  • Patent number: 10584201
    Abstract: The present disclosure relates to synthesis of porous polymer networks and applications of such materials. The present disclosure relates to a method of fabricating of a porous polymer network comprising: (a) providing: (i) a first reactant comprising a plurality of compounds comprising at least one acetyl group, said plurality of compounds comprising at least one compound type, and (ii) a second reactant comprising an alkylsulfonic acid, and (b) creating a solution of said reactants, (c) casting said solution in a form, and (d) treating said solution under such conditions so as to produce a porous polymer network.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: March 10, 2020
    Assignee: The Texas A&M University System
    Inventors: Lei Fang, Zi-Hao Guo, Chenxu Wang, Qiang Zhang, Hong-Cai Zhou
  • Publication number: 20200062825
    Abstract: Described herein is the use of elastin-like polypeptides to generate hemoglobin-based oxygen carriers as a means of preventing and treating conditions caused by blood loss or anemia, for example, hemorrhagic shock. Elastin-like polypeptides are capable of creating therapeutically functional fusion proteins through genetic engineering with a therapeutic agent, for example, hemoglobin and biologic equivalent thereof. Specific forms of these fusion proteins have the ability to form into spherical nanoparticles possessing a therapeutically agent at their core. This provides a unique basis for employing elastin-like polypeptides as hemoglobin carriers in the manufacture of blood substitutes.
    Type: Application
    Filed: November 30, 2018
    Publication date: February 27, 2020
    Inventors: Jordan Tremaine Despanie, Hao Guo, John Andrew MacKay
  • Patent number: D931183
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: September 21, 2021
    Assignee: SHENZHEN SHI SHEN YUAN XIN TECHNOLOGY CO., LTD
    Inventor: Jin Hao Guo