Patents by Inventor Hao RAN

Hao RAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies against TL1A and uses thereof
    Patent number: 12780929
    Abstract: The present disclosure provides an isolated antigen-binding protein specifically binding to TNF-like protein A (TL1A), comprising a heavy chain variable region (VH) comprising at least one heavy chain complementarity-determining region (HCDR) comprising an amino acid sequence shown in SEQ ID NO:1, SEQ ID NO:5, or SEQ ID NO:14.
    Type: Grant
    Filed: August 28, 2025
    Date of Patent: November 3, 2026
    Inventors: Jian Huang, Zhenping Zhu, Jian Peng, Liang Tian, Chenpeng Su, Hao Ran
  • ANTI-CD40L ANTIBODY AND USE THEREOF IN TREATMENT OF HUMAN AUTOIMMUNE DISEASES
    Publication number: 20260297206
    Abstract: The present invention relates to a novel antibody and an antibody fragment that specifically binds to CD40L, as well as a composition comprising the antibody or the antibody fragment. The present invention further relates to a nucleic acid encoding the antibody or the antibody fragment thereof, and a host cell comprising the same, as well as related uses. Furthermore, the present invention relates to therapeutic and diagnostic uses of the antibodies and the antibody fragments.
    Type: Application
    Filed: April 26, 2024
    Publication date: October 1, 2026
    Applicant: FORTVITA BIOLOGICS INC.
    Inventors: Hao RAN, Shiyi WANG, Chenglin HE, Lei CAO
  • ANTIBODY AND USE THEREOF
    Publication number: 20260062471
    Abstract: The present application provides an isolated antigen-binding protein, comprising: a first antigen-binding domain and a second antigen-binding domain, wherein the first antigen-binding domain specifically binds to TNF-like protein A (TL1A), and the first antigen binding domain and the second antigen binding domain are different.
    Type: Application
    Filed: August 28, 2025
    Publication date: March 5, 2026
    Inventors: Hao RAN, Jian HUANG, Zhenping ZHU, Jian PENG, Liang TIAN, Rui SHEN
  • ANTIBODIES AGAINST TL1A AND USES THEREOF
    Publication number: 20260062492
    Abstract: The present disclosure provides an isolated antigen-binding protein specifically binding to TNF-like protein A (TL1A), comprising a heavy chain variable region (VH) comprising at least one heavy chain complementarity-determining region (HCDR) comprising an amino acid sequence shown in SEQ ID NO:1, SEQ ID NO:5, or SEQ ID NO:14.
    Type: Application
    Filed: August 28, 2025
    Publication date: March 5, 2026
    Inventors: Jian HUANG, Zhenping ZHU, Jian PENG, Liang TIAN, Chenpeng SU, Hao RAN
  • BISPECIFIC ANTIBODY AND USE THEREOF
    Publication number: 20260062472
    Abstract: The present application provides an isolated antigen-binding protein, comprising: a first binding domain and a second binding domain, wherein the first binding domain specifically binds to TNF-like protein A (TL1A), and the first binding domain and the second binding domain are different.
    Type: Application
    Filed: August 28, 2025
    Publication date: March 5, 2026
    Inventors: Hao RAN, Jian HUANG, Zhenping ZHU, Jian PENG, Liang TIAN