Patents by Inventor Hao Zhu
Hao Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250236868Abstract: Disclosed herein are compositions comprising siRNAs capable of downregulating Cell Death-Inducing DFF45-like Effector Protein B (CIDEB) gene expression or a variant thereof. Also disclosed herein are methods of using such compositions in the treatment of a liver disease or injury, such as fatty liver disease (FLD), non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).Type: ApplicationFiled: April 7, 2023Publication date: July 24, 2025Inventors: Hao Zhu, Zixi Wang, Lin Li
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Publication number: 20250228885Abstract: Disclosed herein are compositions comprising siRNAs capable of downregulating Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) gene expression or a variant thereof. Also disclosed herein are methods of using such compositions in the treatment of a liver disease or injury, such as fatty liver disease (FLD), non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).Type: ApplicationFiled: April 7, 2023Publication date: July 17, 2025Inventors: Hao Zhu, Zixi Wang, Lin Li
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Publication number: 20250209765Abstract: Provided is a model arrangement information determination method, including: in response to triggering to arrange a first model on a house layout design drawing, displaying at least one capture element of the first model; in response to detecting a drag operation on a first capture element among the at least one capture element, moving the first capture element and the first model according to a trajectory corresponding to the drag operation and a relative position between the first capture element and the first model; and if a preset adsorption condition is met between the first reference line and the first capture element and an arrangement confirmation instruction input by a user is detected during movement, determining an arrangement position of the first capture element based on the first reference line, and determining an arrangement position of the first model based on the first capture element and the first model.Type: ApplicationFiled: December 24, 2024Publication date: June 26, 2025Applicant: Hangzhou Qunhe Information Technology Co., LtdInventors: Hao ZHU, Jiandong ZHOU, Taoyang XU, Yifan LIN, Biao ZHANG, Yujing YANG, Jing GUO
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Patent number: 12336765Abstract: A ray-free dental X-ray periapical film virtual imaging method based on virtual reality (VR) includes: constructing a VR positioning system, and tracing a position of a tracker bonded bound with a tube of a dental film machine and a spatial attitude matrix in real time; scanning and reconstructing a digital three-dimensional (3D) model of dentition; respectively setting different materials and transparency for a shell of a tooth model and an internal pulp cavity; constructing a virtual environment of a simulated oral cavity; assigning an attitude and position of the tracker to a virtual camera by using a network communication module, and controlling the virtual camera to move; placing the tracker in a specific position and orientation to calibrate so as to obtain a position coordinate of a dentition model in the virtual environment; and aligning the tube to teeth, and rendering a virtual periapical film.Type: GrantFiled: July 14, 2020Date of Patent: June 24, 2025Assignee: NANJING UNIVERSITYInventors: Xun Cao, Yidi Zhang, Hao Zhu, Zhuoyi Liao, Weibin Sun
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Patent number: 12332212Abstract: A method for characterizing the gas load of a medium, which comprises a liquid loaded with gas, using a measurement sensor that guides the medium in at least one vibrating measurement tube, includes: determining a speed of sound value and a resonator density value of the medium based on natural frequencies of at least two different vibration modes of the measurement tube; determining a measured pressure value for the medium guided in the measurement tube; determining a gas volume content of suspended bubbles in the medium based on the resonator density value, the speed of sound value and the measured pressure value; and determining a value for the gas volume content of free bubbles based on the resonator density value of the medium and the gas volume content of suspended bubbles.Type: GrantFiled: December 1, 2020Date of Patent: June 17, 2025Assignee: Endress+Hauser Flowtec AGInventors: Hao Zhu, Yaoying Lin, Andreas Güttler
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Patent number: 12325600Abstract: A stacking and palletizing device includes a cassette conveying mechanism, a product transporting and flipping mechanism, a product disc stacking mechanism, and a pallet feeding mechanism. The cassette conveying mechanism is provided thereon with an blank disc receiving station, a product loading station and a product disc stacking station; the product loading station is correspondingly provided with a cassette positioning mechanism; a cassette lifting and partitioning mechanism is disposed below the product disc stacking station; the product disc stacking mechanism includes a screw rod lifting mechanism, which is provided thereon with a palletizing and conveying mechanism; and a gantry truss transplanting mechanism is correspondingly disposed above the screw rod lifting mechanism.Type: GrantFiled: December 12, 2023Date of Patent: June 10, 2025Assignee: Baiqida Intelligent Technology (Ningbo) Co., Ltd.Inventors: Xingjie Wang, Wenzhong Zhou, Kaixuan Yu, Huihe Fang, Niansheng Zhou, Daoyang Liao, Hanquan Wang, Jian Cao, Jianfeng Xin, Hao Zhu, Keqi Zheng, Xiongpeng Zhu, Lei Zhang, Jianli Zhu
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Patent number: 12313435Abstract: A method for operating a Coriolis measurement device comprises the following steps: recording the measured voltages of sensors for sensing measuring tube vibrations and creating an asymmetric sequence of values by way of the amplitudes of the measured voltages for the purpose of diagnosing the Coriolis measurement device, recording at least one stabilization variable and creating a stabilized asymmetric sequence of values based on the stabilization variable, wherein the stabilization variable is one of the following variables or a first or further temporal derivative thereof: a resonant frequency of the measuring tube containing medium or a variable derived therefrom, time or phase difference between measurement signals from the first sensor and the second sensor or a variable derived therefrom, temperature of the measuring tube wall, temperature difference between two measurement points of the measuring tube wall.Type: GrantFiled: March 8, 2021Date of Patent: May 27, 2025Assignee: Endress+Hauser Flowtec AGInventors: Johan Pohl, Hao Zhu
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Patent number: 12317295Abstract: This disclosure describes an architecture for supporting MBS sessions in a wireless access network. Each of such MBS sessions is flexibly and dynamically delivered by the access network into one or more Point-To-Point (PTP, or unicast) and Point-To-Multipoint (PTM, or multicast) delivery instances. As such, a subset of the UEs participating in the MBS may be configured to receive the MBS session in a PTP-like manner and quality. The architecture further allows for access network level switching of one or more of the UEs participating in the MBS session between the PTP mode and PTM mode. Such switching are effectuated dynamically without involvement of application layer. The resource allocations and configuration for the PTP and PTM delivery instances may be performed in the access network collaboratively between a central unit (CU) and one or more distributed units (DUs).Type: GrantFiled: October 21, 2022Date of Patent: May 27, 2025Assignee: ZTE CorporationInventors: Tao Qi, Lin Chen, Liping Wang, Hao Zhu, Kun Cao
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Publication number: 20250154037Abstract: An integrated synchronous nitrogen and sulfur removal device and a wastewater treatment method includes a reactor. A partition plate is horizontally arranged in the reactor to divide the reactor into a first reaction area and a second reaction area which are arranged up and down. An annular baffle plate with a height is arranged in the first reaction area to divide the first reaction area into a first reaction chamber and a second reaction chamber, and a hollow columnar carrier is arranged in the first reaction chamber, so that a third reaction chamber is formed in the first reaction chamber, and the hollow columnar carrier is made of biological stuffing. A water inlet of the reactor is arranged above the first reaction chamber, an anode and a cathode are arranged in the third reaction chamber.Type: ApplicationFiled: April 16, 2024Publication date: May 15, 2025Inventors: You-Peng CHEN, Bin-Hao ZHU, Peng YAN, Yu SHEN, Hui-Min FU, Man-Yi SHI
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Patent number: 12287349Abstract: A measuring transducer includes a tube arrangement having a bent tube, an equally embodied tube, a bent tube and a tube embodied equally to the tube, and two flow dividers each having four flow openings. The measuring transducer includes an exciter for exciting and maintaining mechanical oscillations of the tube arrangement and a sensor for registering mechanical oscillations of the tube arrangement and for producing oscillation measuring signals. Each tube is connected to each flow divider to form four parallel flow paths, having a straight segment connected with the flow divider, an arc shaped segment following such straight segment, a straight segment following such arc shaped segment, an arc shaped segment following such straight segment, a straight segment following such arc shaped segment, an arc shaped segment following such straight segment, and a straight segment following such arc shaped segment and is connected with the flow divider.Type: GrantFiled: November 15, 2018Date of Patent: April 29, 2025Assignee: Endress+Hauser Flowtec AGInventors: Hao Zhu, Alfred Rieder, Ennio Bitto, Gerhard Eckert
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Publication number: 20250093189Abstract: A measuring device for determining density, mass flow rate and/or viscosity of a flowable medium includes: an oscillator including at least one oscillatable measuring tube for conveying the medium, and having at least one oscillatory mode, whose eigenfrequency depends on density of the medium; an exciter for exciting the oscillatory mode; at least one oscillation sensor for registering oscillations of the oscillator; and an operating-evaluating circuit, which is adapted to supply the exciter with an excitation signal, to register signals of the oscillation sensor, based on the signals of the oscillation sensor to ascertain current values of the eigenfrequency of the oscillator as well as variations of the eigenfrequency, and to determine a value characterizing density variations of the medium, wherein the value depends on a function, which is proportional to the variation of the eigenfrequency and has an eigenfrequency dependent normalization.Type: ApplicationFiled: October 18, 2024Publication date: March 20, 2025Inventors: Hao Zhu, Alfred Rieder, Yaoying Lin, Robert Lalla, Reinhard Huber
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Publication number: 20250095913Abstract: An electric press with disc stacking, includes two sets of all-electric presses, a blank disc transporting and stacking all-in-one machine, and a control box. The blank disc transporting and stacking all-in-one machine includes a blank disc feeding mechanism, a cassette conveying mechanism, a product transporting and flipping mechanism, a product disc stacking mechanism, and a pallet feeding mechanism. During operation, the blank disc feeding mechanism feeds blank disc to a blank disc receiving station; the cassette conveying mechanism conveys the blank discs to a product loading station and install products in the blank discs; pallets are transported to the product disc stacking mechanism; the cassette conveying mechanism conveys the pallets with products loaded to a disc stacking station for a disc stacking operation, and after the disc stacking, conveys the products into the pallets for palletization.Type: ApplicationFiled: December 11, 2023Publication date: March 20, 2025Inventors: Niansheng ZHOU, Huihe FANG, Kaixuan YU, Wenzhong ZHOU, Xingjie WANG, Daoyang LIAO, Keqi ZHENG, Xiongpeng ZHU, Lei ZHANG, Jian CAO, Jianfeng XIN, Hao ZHU, Jianli ZHU
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Publication number: 20250091821Abstract: A stacking and palletizing device includes a cassette conveying mechanism, a product transporting and flipping mechanism, a product disc stacking mechanism, and a pallet feeding mechanism. The cassette conveying mechanism is provided thereon with an blank disc receiving station, a product loading station and a product disc stacking station; the product loading station is correspondingly provided with a cassette positioning mechanism; a cassette lifting and partitioning mechanism is disposed below the product disc stacking station; the product disc stacking mechanism includes a screw rod lifting mechanism, which is provided thereon with a palletizing and conveying mechanism; and a gantry truss transplanting mechanism is correspondingly disposed above the screw rod lifting mechanism.Type: ApplicationFiled: December 12, 2023Publication date: March 20, 2025Inventors: Xingjie WANG, Wenzhong ZHOU, Kaixuan YU, Huihe FANG, Niansheng ZHOU, Daoyang LIAO, Hanquan WANG, Jian CAO, Jianfeng XIN, Hao ZHU, Keqi ZHENG, Xiongpeng ZHU, Lei ZHANG, Jianli ZHU
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Patent number: 12241174Abstract: A method used to repair a workpiece through a combination of laser and an electrochemical reaction is provided. A tool anode is arranged on the back side of the workpiece and is spaced therefrom. A laser beam is focused on an outer surface of the workpiece to realize localized repairing on the back side. The method realizes localized coating repairing on the back side of the workpiece through coordination between the thermal effect of the laser and the electrochemical deposition based on the characteristic of high thermal conductivity of the workpiece. The electrodeposition reaction does not occur in regions that do not need to be repaired. The operating process is simple, the cost of the plating solution is largely reduced, and the problem that the coating on the inner wall of the thin-walled workpiece is difficult to repair due to stripping is solved.Type: GrantFiled: May 31, 2022Date of Patent: March 4, 2025Assignee: JIANGSU UNIVERSITYInventors: Kun Xu, Zhihao Leng, Yangfan Tang, Sheng Guo, Zhaoyang Zhang, Hao Zhu, Yang Liu, Yucheng Wu, Wenhui Liang, Panzhou Li
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Publication number: 20250067586Abstract: The method determines a characteristic passage time of a component of a flowing medium in a vibrating measuring tube of a Coriolis mass flow meter. The flow meter has the measuring tube, an exciter for exciting a bending vibration mode of the measuring tube, and a vibration sensor for sensing the measuring tube vibrations. The component is present inhomogenously in the medium and has a component density which deviates from an average density of the medium. The method includes feeding an excitation signal to the exciter with a natural frequency a bending vibration mode, ascertaining at least one first time profile of a signal amplitude of the first vibration sensor at a natural frequency of an anti-symmetrical bending vibration mode, and ascertaining the characteristic passage time on the basis of the first time profile of the signal amplitude at the natural frequency of the anti-symmetrical bending vibration mode.Type: ApplicationFiled: December 2, 2022Publication date: February 27, 2025Inventors: Hao Zhu, Alfred Rieder, Wolfgang Drahm, Yaoying Lin
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Patent number: 12228441Abstract: The present disclosure relates to a method used to monitor a Coriolis mass flow meter, which has an oscillator with at least one measurement tube, the method including: exciting the oscillator so as to cause flexural vibrations of a first antisymmetric vibration mode by an excitation signal at a resonance frequency of the first antisymmetric vibration mode; sensing a vibration amplitude of the first antisymmetric vibration mode at the resonance frequency of the first antisymmetric vibration mode; sensing a time constant of the decaying free vibrations of the first antisymmetric vibration mode; and determining a modal elastic property of the oscillator with respect to the first antisymmetric vibration mode on the basis of the vibration amplitude of the first antisymmetric vibration mode, the excitation signal, and the time constant.Type: GrantFiled: March 23, 2021Date of Patent: February 18, 2025Assignee: Endress+Hauser Flowtec AGInventors: Alfred Rieder, Hao Zhu
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Patent number: 12215993Abstract: A method includes registering a first mass flow rate portion measurement value {dot over (m)}1 of a first flow portion through measuring tubes of a first oscillator and a second mass flow rate portion measurement value {dot over (m)}2 of a second flow portion through measuring tubes of the second oscillator. A sum of the two mass flow rate portion measurement values gives a mass flow rate total measurement value. The method also includes registering first and second density portion measurement values ?1, ?2 of the medium in the flow portions and calculating the effective density measurement value peff as a function of the density portion measurement values ?1, ?2 with weightings dependent on the mass flow rate portion measurement values {dot over (m)}1, {dot over (m)}2. The different weighting functions are applied for ascertaining the weightings as a function of the mass flow rate portion measurement values.Type: GrantFiled: April 23, 2021Date of Patent: February 4, 2025Assignee: Endress+Hauser Flowtec AGInventor: Hao Zhu
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Publication number: 20250020563Abstract: A method for detecting a foreign body in a flowable medium includes determining a first time curve of a first measured value using a first measuring device for determining a physical density of the medium. The method also includes determining a second time curve of a second measured value using a second measuring device for ascertaining a relative permittivity of the medium. A temporal correlation between the first curve and the second curve is determined, and pairs of measured values of the first measured value and the second measured value are detected. The method further includes checking whether the detected pairs of measured values within a predefined tolerance interval correspond to the correlation of at least one predefined function. If this is not the case, it is established that the foreign body is present in the medium.Type: ApplicationFiled: November 28, 2022Publication date: January 16, 2025Inventors: Stefan Pflüger, Hao Zhu, Wolfgang Drahm
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Patent number: 12189561Abstract: A multi-format graphics process unit (GPU) docking board is disclosed. The multi-format GPU docking board includes a first switch to enable communication between a first format (GPU) board and a second format GPU board, and a second switch to enable communication between a central processing unit (CPU) and the first format GPU board and between the CPU and the second format GPU board.Type: GrantFiled: July 31, 2020Date of Patent: January 7, 2025Assignee: Nvidia CorporationInventors: Xiaozhuo Cai, Shuanghu Yan, Hao Zhu, Dinghai Yi
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Patent number: 12185194Abstract: The present disclosure describes methods, system, and devices for selecting a radio bearer mode for multicast broadcast services (MBS). The method includes informing a radio access network (RAN) that a user equipment (UE) is receiving/interested to receive or no longer receiving/interested to receive multicast broadcast service (MBS) services via a cast mode. The method includes sending, by the UE, MBS interest information to the RAN, the MBS interest information comprising a list of MBS services of interest.Type: GrantFiled: October 11, 2022Date of Patent: December 31, 2024Assignee: ZTE CORPORATIONInventors: Hao Zhu, Lin Chen, Zijiang Ma, Tao Qi, Feng Xie, Ying Huang