Patents by Inventor Haohan Tan

Haohan Tan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20230406856
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 16, 2021
    Publication date: December 21, 2023
    Inventors: Haohan TAN, Qihong LIU, Yunling WANG, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS AS BCL-2 INHIBITORS
    Publication number: 20230159527
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: May 7, 2021
    Publication date: May 25, 2023
    Inventors: Weipeng ZHANG, Hongbin LIU, Rui TAN, Zhifu LI, Yue RONG, Qihong LIU, Zhifang CHEN, Ling CHEN, Hua XU, Zuwen ZHOU, Jinhua YU, Haohan TAN, Bin LIU, Yunling WANG, Lijun YANG, Chengxi HE, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS USEFUL AS KINASE INHIBITORS
    Publication number: 20230145305
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 10, 2021
    Publication date: May 11, 2023
    Inventors: Chengxi HE, Xianlong WANG, Yue RONG, Rui TAN, Huajie ZHANG, Haohan TAN, Yanxin LIU, Shu LIN, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • Macrocyclic compounds as TRK kinases inhibitors
    Patent number: 11555042
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: January 17, 2023
    Assignee: Fochon Biosciences, Ltd.
    Inventors: Huajie Zhang, Qihong Liu, Chengxi He, Weipeng Zhang, Rui Tan, Bin Liu, Hong Fu, Haohan Tan, Lijun Yang, Hongbin Liu, Yunling Wang, Yuwei Gao, Zongyao Zou, Yanxin Liu, Shu Lin, Tongshuang Li, Xingdong Zhao, Weibo Wang
  • APOPTOSIS-INDUCING AGENTS
    Publication number: 20220402913
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: July 15, 2021
    Publication date: December 22, 2022
    Inventors: Hongbin LIU, Yue RONG, Huajie ZHANG, Zhifang CHEN, Rui TAN, Chengxi HE, Zhifu LI, Zuwen ZHOU, Haohan TAN, Kai RAN, Xianlong WANG, Zongyao ZOU, Lihua JIANG, Yanxin LIU, Xingdong ZHAO, Weibo WANG, Jiemin FU
  • HETEROCYCLIC DERIVATIVES AND USE THEREOF
    Publication number: 20220354860
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: June 15, 2020
    Publication date: November 10, 2022
    Inventors: Zuwen ZHOU, Hua XU, Yue RONG, Ling CHEN, Zhifang CHEN, Rui TAN, Lijun YANG, Xianlong WANG, Haohan TAN, Bin LIU, Chenglin ZHOU, Yuwei GAO, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Substituted 2-azabicyclo[3.1.0]hexanes as TRK kinases inhibitors
    Patent number: 11459332
    Abstract: Provided are certain TRK inhibitors of formula (I): pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: October 4, 2022
    Assignee: Fochon Biosciences, Ltd.
    Inventors: Hongbin Liu, Haohan Tan, Chengxi He, Xianlong Wang, Qihong Liu, Zhifu Li, Zuwen Zhou, Yuwei Gao, Lihua Jiang, Li Linghu, Shu Lin, Xingdong Zhao, Weibo Wang
  • SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3,4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20220235049
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: June 1, 2020
    Publication date: July 28, 2022
    Inventors: Haohan TAN, Qihong LIU, Bin LIU, Zhifu LI, Xianlong WANG, Zuwen ZHOU, Weipeng ZHANG, Yunling WANG, Chenglin ZHOU, Yuwei GAO, Lihua JIANG, Yanxin LIU, Zongyao ZOU, Shu LIN, Kai YU, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • Sulfoximine, sulfonimidamide, sulfondiimine and diimidosulfonamide compounds as inhibitors of indoleamine 2,3-dioxygenase
    Patent number: 11168078
    Abstract: Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: November 9, 2021
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Zhifang Chen, Rui Tan, Qihong Liu, Lijun Yang, Zhifu Li, Haohan Tan, Hongbin Liu, Xingdong Zhao, Min Lin, Jing Sun, Weibo Wang
  • Apoptosis-inducing agents
    Patent number: 11091478
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: August 17, 2021
    Assignee: Fochon Pharmaceutical Co., Ltd.
    Inventors: Hongbin Liu, Yue Rong, Huajie Zhang, Zhifang Chen, Rui Tan, Chengxi He, Zhifu Li, Zuwen Zhou, Haohan Tan, Kai Ran, Xianlong Wang, Zongyao Zou, Lihua Jiang, Yanxin Liu, Xingdong Zhao, Weibo Wang, Jiemin Fu
  • Compounds as BLC-2-selective apoptosis-inducing agents
    Patent number: 11053239
    Abstract: Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bcl-2 inhibitors can be used to treat cell proliferative disorders.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: July 6, 2021
    Assignee: Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Zuwen Zhou, Chengxi He, Zhifu Li, Yue Rong, Rui Tan, Huajie Zhang, Hongbin Liu, Weipeng Zhang, Haohan Tan, Zhifang Chen, Lihua Jiang, Yanxin Liu, Min Lin, Jing Sun, Weibo Wang
  • MACROCYCLIC COMPOUNDS AS TRK KINASES INHIBITORS
    Publication number: 20210139506
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 27, 2019
    Publication date: May 13, 2021
    Applicants: Fochon Pharmaceuticals, Ltd., Shanghai Fochon Pharmaceutical Co., LTD.
    Inventors: Huajie ZHANG, Qihong LIU, Chengxi HE, Weipeng ZHANG, Rui TAN, Bin LIU, Hong FU, Haohan TAN, Lijun YANG, Hongbin LIU, Yunling WANG, Yuwei GAO, Zongyao ZOU, Yanxin LIU, Shu LIN, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • SULFOXIMINE, SULFONIMIDAMIDE, SULFONDIIMINE AND DIIMIDOSULFONAMIDE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE
    Publication number: 20210070742
    Abstract: Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
    Type: Application
    Filed: November 28, 2017
    Publication date: March 11, 2021
    Inventors: Zhifang CHEN, Rui TAN, Qihong LIU, Lijun YANG, Zhifu LI, Haohan TAN, Hongbin LIU, Xingdong ZHAO, Min LIN, Jing SUN, Weibo WANG
  • SUBSTITUTED (2-AZABICYCLO[3.1.0]HEXAN-2-YL)PYRAZOLO[1,5-a]PYRIMIDINE AND IMIDAZO[1,2-b]PYRIDAZINE COMPOUNDS AS TRK KINASES INHIBITORS
    Publication number: 20210024528
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 13, 2019
    Publication date: January 28, 2021
    Inventors: Hongbin LIU, Haohan TAN, Chengxi HE, Xianlong WANG, Qihong LIU, Zhifu LI, Zuwen ZHOU, Yuwei GAO, Lihua JIANG, Li LINGHU, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Indolizine derivatives, composition and methods of use
    Patent number: 10894038
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: January 19, 2021
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO. LTD., FOCHON PHARMACEUTICALS, LTD.
    Inventors: Tongshuang Li, Xingdong Zhao, Chuiliang Yu, Haohan Tan, Xianlong Wang, Rui Tan, Bin Liu, Weipeng Zhang, Huajie Zhang, Qihong Liu, Zuwen Zhou, Zhifu Li, Yue Rong, Jing Sun, Weibo Wang
  • Substituted pyrrolo[2,3-d]pyridazin-4-ones and pyrazolo[3,4-d]pyridazin-4-ones as protein kinase inhibitors
    Patent number: 10800785
    Abstract: Provided are certain compounds or pharmaceutically acceptable salts thereof which can inhibit kinase activity of Bruton's tyrosine kinase (BTK) and may be useful for the treatment of diseases like cancer, immunological disease and inflammation.
    Type: Grant
    Filed: June 20, 2017
    Date of Patent: October 13, 2020
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong Zhao, Weipeng Zhang, Zhifang Chen, Ling Chen, Xianlong Wang, Zhifu Li, Rui Tan, Lijun Yang, Haohan Tan, Bin Liu, Kai Ran, Zongyao Zou, Min Lin, Jing Sun, Weibo Wang
  • APOPTOSIS-INDUCING AGENTS
    Publication number: 20200115379
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: April 17, 2018
    Publication date: April 16, 2020
    Inventors: Hongbin LIU, Yue RONG, Huajie ZHANG, Zhifang CHEN, Rui TAN, Chengxi HE, Zhifu LI, Zuwen ZHOU, Haohan TAN, Kai RAN, Xianlong WANG, Zongyao ZOU, Lihua JIANG, Yanxin LIU, Xingdong ZHAO, Weibo WANG, Jiemin FU
  • INDOLIZINE DERIVATIVES, COMPOSITION AND METHODS OF USE
    Publication number: 20200113876
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Application
    Filed: December 26, 2016
    Publication date: April 16, 2020
    Inventors: Tonshuang LI, Xingdong ZHAO, Chuiliang YU, Haohan TAN, Xianlong WANG, Rui TAN, BIN LIU, Weipeng ZHANG, Huajie ZHANG, Qihong LIU, Zuwen ZHOU, Zhifu LI, Yue RONG, Jing SUN, Weibo WANG
  • COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS
    Publication number: 20190345156
    Abstract: Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bc1-2 inhibitors can be used to treat cell proliferative disorders.
    Type: Application
    Filed: January 5, 2018
    Publication date: November 14, 2019
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Xingdong ZHAO, Zuwen ZHOU, Chengxi HE, Zhifu LI, Yue RONG, Rui TAN, Huajie ZHANG, Hongbin LIU, Weipeng ZHANG, Haohan TAN, Zhifang CHEN, Lihua JIANG, Yanxin LIU, Min LIN, Jing SUN, Weibo WANG
  • Certain protein kinase inhibitor
    Patent number: 10450316
    Abstract: Provided are certain CDK4/6 inhibitors with the structure of formula (I), pharmaceutical compositions thereof, and methods of use therefor. The compounds are of the class of pyrimidin-2 amine derivatives, useful for the treatment of hyper-proliferative diseases.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: October 22, 2019
    Assignees: CHONGQING FOCHON PHARMACEUTICAL CO., LTD., SHANGHAI FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Xingdong Zhao, Tongshuang Li, Haohan Tan, Zhifang Chen, Ling Chen, Qihong Liu, Yue Rong, Lijun Yang, Xianlong Wang, Rui Tan, Zuwen Zhou, Bin Liu, Min Lin, Lihua Jiang, Yanxin Liu, Li Linghu, Jing Sun, Weibo Wang