Patents by Inventor Haoheng Yan

Haoheng Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for isolating microvesicles and extracting nucleic acids from biological samples
    Patent number: 11268085
    Abstract: The invention provides novel methods and kits for isolating nucleic acids from biological samples, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from microvesicles, and for extracting nucleic acids from the microvesicles and/or from the biological samples.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: March 8, 2022
    Assignee: Exosome Diagnostics, Inc.
    Inventors: Johan Karl Olov Skog, Daniel Enderle, Aparna Ramachandran, Haoheng Yan, Emily Berghoff, Tai-Fen Wei, Mikkel Noerholm
  • METHODS FOR ISOLATING MICROVESICLES
    Publication number: 20210171934
    Abstract: The invention provides novel methods for isolating microvesicles from a biological sample and for extracting nucleic acids from the microvesicles.
    Type: Application
    Filed: June 5, 2020
    Publication date: June 10, 2021
    Inventors: Daniel ENDERLE, Aparna RAMACHANDRAN, Haoheng YAN, Emily BERGHOFF, Tai-Fen WEI, Mikkel NOERHOLM, Johan Karl Olov SKOG
  • METHODS FOR ISOLATING MICROVESICLES AND EXTRACTING NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES
    Publication number: 20200032243
    Abstract: The invention provides novel methods and kits for isolating nucleic acids from biological samples, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from microvesicles, and for extracting nucleic acids from the microvesicles and/or from the biological samples.
    Type: Application
    Filed: October 7, 2019
    Publication date: January 30, 2020
    Inventors: Johan Karl Olov SKOG, Daniel ENDERLE, Aparna RAMACHANDRAN, Haoheng YAN, Emily BERGHOFF, Tai-Fen WEI, Mikkel NOERHOLM
  • Methods for isolating microvesicles and extracting nucleic acids from biological samples
    Patent number: 10465183
    Abstract: The invention provides novel methods and kits for isolating nucleic acids from biological samples, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from microvesicles, and for extracting nucleic acids from the microvesicles and/or from the biological samples.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: November 5, 2019
    Assignee: Exosome Diagnostics, Inc.
    Inventors: Johan Karl Olov Skog, Daniel Enderle, Aparna Ramachandran, Haoheng Yan, Emily Berghoff, Tai-Fen Wei, Mikkel Noerholm
  • METHODS FOR ISOLATING MICROVESICLES AND EXTRACTING NUCLEIC ACIDS FROM BIOLOGICAL SAMPLES
    Publication number: 20170198280
    Abstract: The invention provides novel methods and kits for isolating nucleic acids from biological samples, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from microvesicles, and for extracting nucleic acids from the microvesicles and/or from the biological samples.
    Type: Application
    Filed: July 9, 2015
    Publication date: July 13, 2017
    Inventors: Johan Karl Olov Skog, Daniel Enderle, Aparna Ramachandran, Haoheng Yan, Emily Berghoff, Tai-Fen Wei, Mikkel Noerholm
  • METHODS FOR ISOLATING MICROVESICLES
    Publication number: 20150353920
    Abstract: The invention provides novel methods for isolating microvesicles from a biological sample and for extracting nucleic acids from the microvesicles.
    Type: Application
    Filed: January 3, 2014
    Publication date: December 10, 2015
    Inventors: Daniel Enderle, Aparna Ramachandran, Haoheng Yan, Emily Berghoff, Tai-Fen Wei, Mikkel Noerholm, Johan Karl Olav Skog
  • USE OF MICROVESICLES IN DIAGNOSIS, PROGNOSIS, AND TREATMENT OF MEDICAL DISEASES AND CONDITIONS
    Publication number: 20150252428
    Abstract: The present invention discloses methods for diagnosing or prognosing a disease or medical condition in a subject by detecting the presence or absence of BRAF mutant nucleic acids from nucleic acids extracted from microvesicles from a biological sample. The present invention also discloses methods for assessing the responsiveness or determining a treatment regimen for a subject in need thereof by detecting the presence or absence of BRAF mutant nucleic acids from nucleic acids extracted from microvesicles from a biological sample. Methods for isolating microvesicles and extracting DNA and/or RNA from the microvesicles are also described.
    Type: Application
    Filed: October 3, 2013
    Publication date: September 10, 2015
    Inventors: Wayne Comper, Aparna Ramachandran, Haoheng Yan, Leileata M. Russo, Johan Karl Olav Skog