Abstract: A method for detecting image information includes: acquiring at least one sample of image pair to be processed; calculating a reconstruction loss function of the second feature extraction model based on the first image samples and the first reconstructed image feature information; calculating an adversarial loss function of the third feature extraction model based on the second reconstructed image feature information and the first image samples; optimizing the first model parameters in the first feature extraction model based on the reconstruction and the adversarial loss function to generate the optimized first feature extraction model; inputting the acquired image pair to be processed into the optimized first feature extraction model to generate the difference information. The method reduces the first feature extraction model's dependence on the labeled data and improves the model's recognition efficiency and accuracy by using the samples without the labeled difference information.

Abstract: Provided are a PCR primer pair and an application thereof.

Abstract: A method for detecting image information includes: acquiring at least one sample of image pair to be processed; calculating a reconstruction loss function of the second feature extraction model based on the first image samples and the first reconstructed image feature information; calculating an adversarial loss function of the third feature extraction model based on the second reconstructed image feature information and the first image samples; optimizing the first model parameters in the first feature extraction model based on the reconstruction and the adversarial loss function to generate the optimized first feature extraction model; inputting the acquired image pair to be processed into the optimized first feature extraction model to generate the difference information. The method reduces the first feature extraction model's dependence on the labeled data and improves the model's recognition efficiency and accuracy by using the samples without the labeled difference information.

Abstract: A method for rapidly preparing a Sanger sequencing template, comprising: performing denaturing treatment on a sample containing circular DNAs; performing rolling circle amplification of the denaturing product; and treating the rolling circle amplification product with alkaline phosphatase to remove residual dNTP.

Abstract: The present application provides a method for quickly homogenizing circular DNA samples, comprising performing rolling circle amplification on circular DNAs in the samples, so that the concentration of the circular DNAs in the samples are homogenized.

Abstract: Provided are a PCR primer pair and an application thereof.

Abstract: Provided are a PCR primer pair and an application thereof. The PCR primer pair comprises a first primer and a second primer, wherein the first primer comprises a first specific sequence, a first random sequence, and a first universal sequence, the first specific sequence is located at the 3? end of the first primer, the first random sequence is located at the 5? end of the first primer, and the first universal sequence is located between the first specific sequence and the first random sequence; the second primer comprises a second specific sequence, a second random sequence, and a second universal sequence, the second specific sequence is located at the 3? end of the second primer, the second random sequence is located at the 5? end of the second primer, and the second universal sequence is located between the second specific sequence and the second random sequence, wherein the first random sequence and the second random sequence are inversely complementary.

Abstract: A method and a device for detecting chromosomal aneuploidy are provided. The method includes: obtaining the distribution of the sequencing result of test samples on a reference sequence, i.e., the number of sequence reads falling within each window divided on the reference sequence, wherein the test samples comprise target samples derived from target individuals and control samples derived from normal individuals; calculating the deviation statistic of each target sample in each window; comparing the average value of the deviation statistics on a certain chromosome of the target samples with a corresponding deviation threshold, and determining whether there is a deletion or duplication in the chromosome according to the comparison results, wherein the deviation threshold is set according to the deviation statistics of all normal individuals on the chromosome.