Abstract: Disclosed is a high anticoagulation extracorporeal circulation tube, which include the following preparation methods: S1, firstly, aminating the surface of the tube by extrusion molding; S2, activating heparin groups by a direct coupling method; S3, heparinizing PVC or PC tubes; S4, then, using albumin, functionalized PEG which can react with amino groups, and phosphate to further surface modify the inner wall of heparinized PVC or PC tube to block the sites not modified by heparinization, so as to shield the adsorption of platelets and protein in blood on the inner wall. The application can produce a novel high anticoagulation extracorporeal circulation tube with low price and high biocompatibility, which expands the application in clinic.

Abstract: Disclosed is a high anticoagulation ECMO and extracorporeal circulation consumable, which include the following preparation methods: S1, aminating the surface of ECMO blood circulation device and extracorporeal circulation consumables; S2, activating heparin groups; S3, heparinizing the ECMO blood circulation device and extracorporeal circulation consumables; S4, modification of enhancer. The application can produce a novel high anticoagulation extracorporeal circulation tube with low price and high biocompatibility, which expands the application in clinic.

Abstract: Disclosed herein is a heuristically programmable system comprising a web-socket; a backend component that is in operative communication with the web-socket to act as a heuristically programmed algorithm framework that is operative to interact with a user in natural language and in a human-like manner; a main frame computer; a web server that is in operative communication with an internet; where the main frame computer and the web server are in operative communication with the web socket; and a cognitive computing system; where the web socket comprises a computer system configured to provide a voice, motion and/or a graphical interface to a user; and where the web socket is operative to communicate with the cognitive computing system; where the cognitive computing system is operative to convert speech to text and to send this text to the web socket.

Abstract: A system for preforming mid-method instrumentation includes a processor; a memory; and one or more modules stored in the memory and executable by a processor to perform operations including: obtain bytecode representation of an application; identify a method in the bytecode including a beginning and an end of the method; identify lines of bytecode between the beginning and the end of the identified method; identify one or more of the lines of bytecode between the beginning and the end of the method to instrument with one or more interceptors; during runtime of the application, instrument the identified one or more of the lines of bytecode between the beginning and the end of the identified method by apply the one or more interceptors; and during the runtime of the application, receive information associated with the instrumented one or more lines of bytecode between the beginning and the end of the method.

Abstract: A system for preforming mid-method instrumentation includes a processor; a memory: and one or more modules stored in the memory and executable by a processor to perform operations including: obtain bytecode representation of an application; identify a method in the bytecode including a beginning and an end of the method; identify lines of bytecode between the beginning and the end of the identified method; identify one or more of the lines of bytecode between the beginning and the end of the method to instrument with one or more interceptors; during runtime of the application, instrument the identified one or more of the lines of bytecode between the beginning and the end of the identified method by apply the one or more interceptors; and daring the runtime of the application, receive information associated with the instrumented one or more lines of bytecode between the beginning and the end of the method.

Abstract: A system for performing mid-method instrumentation includes a processor; a memory; and one or more modules stored in the memory and executable by a processor to perform operations including: obtain bytecode representation of an application; identify a method in the bytecode including a beginning and an end of the method; identify lines of bytecode between the beginning and the end of the identified method; identify one or more of the lines of bytecode between the beginning and the end of the method to instrument with one or more interceptors; during runtime of the application, instrument the identified one or more of the lines of bytecode between the beginning and the end of the identified method by apply the one or more interceptors; and during the runtime of the application, receive information associated with the instrumented one or more lines of bytecode between the beginning and the end of the method.

Abstract: A system for performing mid-method instrumentation includes a processor; a memory; and one or more modules stored in the memory and executable by a processor to perform operations including: obtain bytecode representation of an application; identify a method in the bytecode including a beginning and an end of the method; identify lines of bytecode between the beginning and the end of the identified method; identify one or more of the lines of bytecode between the beginning and the end of the method to instrument with one or more interceptors; during runtime of the application, instrument the identified one or more of the lines of bytecode between the beginning and the end of the identified method by apply the one or more interceptors; and during the runtime of the application, receive information associated with the instrumented one or more lines of bytecode between the beginning and the end of the method.

Abstract: Disclosed herein is a heuristically programmable system comprising a web-socket; a backend component that is in operative communication with the web-socket to act as a heuristically programmed algorithm framework that is operative to interact with a user in natural language and in a human-like manner; a main frame computer; a web server that is in operative communication with an internet; where the main frame computer and the web server are in operative communication with the web socket; and a cognitive computing system; where the web socket comprises a computer system configured to provide a voice, motion and/or a graphical interface to a user; and where the web socket is operative to communicate with the cognitive computing system; where the cognitive computing system is operative to convert speech to text and to send this text to the web socket.

Abstract: Disclosed herein is a heuristically programmable system comprising a web-socket; a backend component that is in operative communication with the web-socket to act as a heuristically programmed algorithm framework that is operative to interact with a user in natural language and in a human-like manner; a main frame computer; a web server that is in operative communication with an internet; where the main frame computer and the web server are in operative communication with the web socket; and a cognitive computing system; where the web socket comprises a computer system configured to provide a voice, motion and/or a graphical interface to a user; and where the web socket is operative to communicate with the cognitive computing system; where the cognitive computing system is operative to convert speech to text and to send this text to the web socket.