Patents by Inventor Haoming Gu

Haoming Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10583119
    Abstract: The present invention provides compounds and/or compositions that modulate PP2A methylation and/or activity and methods for preparing the same, which are useful for modulating the demethylation of PP2A, modulating the methylation of PP2A and/or modulating the activity of PP2A.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: March 10, 2020
    Assignee: Signum Biosciences, Inc.
    Inventors: Scott Vafai, Michael Voronkov, Maxwell Stock, Jeffry B. Stock, Seung-Yub Lee, Zhu Li, Haoming Gu
  • Publication number: 20170266161
    Abstract: The present invention provides compounds and/or compositions that modulate PP2A methylation and/or activity and methods for preparing the same, which are useful for modulating the demethylation of PP2A, modulating the methylation of PP2A and/or modulating the activity of PP2A.
    Type: Application
    Filed: November 8, 2016
    Publication date: September 21, 2017
    Applicant: Signum Biosciences, Inc.
    Inventors: SCOTT VAFAI, Michael Voronkov, Maxwell Stock, Jeffry B. Stock, Seung-Yub Lee, Zhu Li, Haoming Gu
  • Patent number: 9486441
    Abstract: The present invention provides compounds and/or compositions that modulate PP2A methylation and/or activity and methods for preparing the same, which are useful for modulating the demethylation of PP2A, modulating the methylation of PP2A and/or modulating the activity of PP2A.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: November 8, 2016
    Assignee: SIGNUM BIOSCIENCES, INC.
    Inventors: Scott Vafai, Michael Voronkov, Maxwell Stock, Jeffry B. Stock, Seung-Yub Lee, Zhu Li, Haoming Gu
  • Patent number: 8221804
    Abstract: The invention encompasses novel compositions containing a methylation modifying compound isolated from botanical raw materials, including a fruit of the genus Coffea, and microbial raw materials, methods of making such compositions, and methods of treating or preventing human disease using such compositions. The methylation modifying compound in botanical extracts of the present invention can dramatically increase the level of methylation of PP2A, thus increasing cognitive function, particularly in persons suffering from or prone to developing Alzheimer's disease.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: July 17, 2012
    Assignees: Signum Biosciences, Inc., Trustees of Princeton University
    Inventors: Jeffry B. Stock, Maxwell Stock, Haoming Gu, Gregory B Stock, Zhu Li, Peter Michael Wolanin
  • Patent number: 7923041
    Abstract: Disclosed are compositions for promoting general health and well-being, comprising an extract of a botanical raw material, wherein said extract inhibits the carboxyl demethylating activity of a protein phosphatase, and methods of making and using same.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: April 12, 2011
    Assignees: Signum Biosciences, Inc., The Trustees of Princeton University
    Inventors: Jeffry Stock, Maxwell Stock, Haoming Gu, Zhu Li, Peter Wolanin
  • Publication number: 20090264496
    Abstract: The present invention provides compounds and/or compositions that modulate PP2A methylation and/or activity and methods for preparing the same, which are useful for modulating the demethylation of PP2A, modulating the methylation of PP2A and/or modulating the activity of PP2A.
    Type: Application
    Filed: April 21, 2009
    Publication date: October 22, 2009
    Inventors: Scott Vafai, Michael Voronkov, Maxwell Stock, Jeffry B. Stock, Seung-Yub Lee, Zhu Li, Haoming Gu
  • Publication number: 20080213406
    Abstract: Disclosed are compositions for promoting general health and well-being, comprising an extract of a botanical raw material, wherein said extract inhibits the carboxyl demethylating activity of a protein phosphatase, and methods of making and using same.
    Type: Application
    Filed: August 3, 2007
    Publication date: September 4, 2008
    Applicant: SIGNUM BIOSCIENCES, INC.
    Inventors: Jeffry Stock, Maxwell Stock, Haoming Gu, Gregory Stock, Zhu Li, Peter Wolanin