Abstract: A method may capture images of the vehicle lane using a camera attached to a moving vehicle. The method may determine, based on the captured one or more images, locations of a plurality of first lane markings defining a left extent of a lane and a plurality of second lane markings defining a right extent of the lane. The method may project the determined locations in the one or more images to locations in a coordinate system of the roadway. The method may determine a plurality of widths of the lane in the coordinate system of the roadway over a range of distances. The method may determine variations of the lane widths in the coordinate system of the roadway over the range of distances. The method may rescale the lane widths over the range of distances in the coordinate system to reduce determined variations of the lane widths.

Abstract: A double-channel fluid injection apparatus includes a main shaft, a bearing box, and a sealing box. The main shaft includes an outer tube and an inner tube. An internal channel of the inner tube and a vertical through channel constitute a first fluid passageway. The inner tube and the outer tube form an annular gap, and a channel D is radially formed at a lower part of the outer tube and is in communication with the annular gap, thus constituting a second fluid passageway. The bearing box is mounted on a boss of the outer tube. The sealing box includes a sealing cylinder fixedly connected to a lower end of a lower end cap of the bearing box. A channel E in communication with the second fluid passageway is radially formed at a position of the sealing cylinder corresponding to the channel of the outer tube.

Abstract: The present disclosure discloses a B7H6 antibody and use thereof. The antibody includes heavy chain CDR1, heavy chain CDR2 and heavy chain CDR3; and light chain CDR1, light chain CDR2 and light chain CDR3. The antibody of the present disclosure is capable of binding to B7H6, and promoting the binding of B7H6 to the NK cell activating receptor NKp30, with an anti-cancer function.

Abstract: Disclosed is an antibody and use thereof. The antibody or antigen binding fragment includes CDR sequences selected from at least one of heavy-chain variable region CDR sequences: SEQ ID NOs: 1-3; and light-chain variable region CDR sequences: SEQ ID NOs: 4-6. The antibody prepared by the present disclosure can effectively bind to the ?3 domain of MICA or MICB, and further, promote the binding of NKG2D to MICA and/or MICB, and can effectively treat or prevent related diseases mediated by MICA and/or MICB, such as promoting the killing of tumors by NK cell.

Abstract: Provided are a bispecific antibody and use thereof. The recombinant antibody includes: a CDR Sequence selected from at least one of CD3 antibody variable region CDR sequences: SEQ ID NO: 1 to SEQ ID NO: 6, and B7H6 antibody variable region CDR sequences: SEQ ID NO: 7 to SEQ ID NO: 12; or an amino acid sequence having at least 95% identity thereto. The recombinant antibodies prepared according to the present application can simultaneously target CD3 and B7H6 antigens, and they have a. significantly prolonged half-life, exhibiting a stronger tumor-inhibiting ability than single-target antibodies.

Abstract: A flow splitting device for gas reverse circulation drilling, including: an upper joint for connecting with a double-wall drill pipe; an inner tube which is arranged in the upper joint and defines a first passageway in communication with an inner chamber of the double-wall drill pipe, a second passageway in communication with an annular space in the double-wall drill pipe formed between the inner tube and the upper joint; a lower joint, having an upper end fixedly connected with the upper joint and a lower end for connecting with a drill tool; and a flow guiding member provided between the upper joint and the lower joint. A flexible sealing mechanism is provided outside the upper joint. The flexible sealing mechanism extends radially outward relative to the upper joint and the lower joint to form a sealing contact with a wellbore wall.

Abstract: The present disclosure provides a fixed-position defect doping method for a micro-nanostructure based on a self-alignment process, including: S1, sequentially forming a sacrificial layer and a photoresist layer on a surface of a crystal substrate; S2, performing a lithography on the photoresist layer to form a mask hole according to a micro-nano pattern; S3, performing an isotropic etching on the sacrificial layer through the mask hole, and amplifying the micro-nano pattern to the sacrificial layer; S4, performing an ion implantation doping on an exposed crystal surface below the mask hole; S5, removing the photoresist layer, and depositing a mask material; S6, removing the sacrificial layer, and transferring a micro-nano amplified pattern in the sacrificial layer to a mask material pattern; and S7, etching an exposed crystal surface, and removing the mask material on the surface and forming a specific defect by annealing.

Abstract: Provided is an antibody or antibody fragment. The antibody or the antibody fragment includes HCDR1 selected from GYTFSSFS, GYTFSTFA, or GYSFTAYT, HCDR2 selected from ILPGSNST, ILPGINNT, ILPGGNNT, or INPYNGGT, and HCDR3 selected from SSYWFAY, STYWFAY, or AREGNYYGSRGDFDY; and LCDR1 selected from QSLLNSGNQKNY or QTIVTN, LCDR2 selected from GAS or YAS, and LCDR3 selected from QNAHSYPPT, QNAHSYPPA, or QQSHSWPFT. The provided antibody can be used for treating cancer.

Abstract: A flow splitting device for gas reverse circulation drilling, including: an upper joint for connecting with a double-wall drill pipe; an inner tube which is arranged in the upper joint and defines a first passageway in communication with an inner chamber of the double-wall drill pipe, a second passageway in communication with an annular space in the double-wall drill pipe formed between the inner tube and the upper joint; a lower joint, having an upper end fixedly connected with the upper joint and a lower end for connecting with a drill tool; and a flow guiding member provided between the upper joint and the lower joint. A flexible sealing mechanism is provided outside the upper joint. The flexible sealing mechanism extends radially outward relative to the upper joint and the lower joint to form a sealing contact with a wellbore wall.

Abstract: Provided herein, in some embodiments, are cytosine analogs, compositions comprising cytosine analogs, and methods of use for inhibiting a Ten-eleven translocation (TET) enzyme.

Abstract: A double-channel fluid injection apparatus includes a main shaft, a bearing box, and a sealing box. The main shaft includes an outer tube and an inner tube. An internal channel of the inner tube and a vertical through channel constitute a first fluid passageway. The inner tube and the outer tube form an annular gap, and a channel D is radially formed at a lower part of the outer tube and is in communication with the annular gap, thus constituting a second fluid passageway. The bearing box is mounted on a boss of the outer tube. The sealing box includes a sealing cylinder fixedly connected to a lower end of a lower end cap of the bearing box. A channel E in communication with the second fluid passageway is radially formed at a position of the sealing cylinder corresponding to the channel of the outer tube.

Abstract: A computer-implemented method for controlling a vehicle system of a host vehicle merging into a lane. The method includes determining an actual distance between the host vehicle and the one or more remote vehicles. The actual distance is a longitudinal distance between the host vehicle and the one or more remote vehicles. The method includes determining a safe distance for merging into the lane based on a relative position of the host vehicle to the one or more remote vehicles, a speed of the host vehicle, and a speed of the one or more remote vehicles. The safe distance is a second longitudinal distance between the host vehicle and the one or more remote vehicles. The method includes controlling the vehicle system of the host vehicle to assist a merge maneuver by the host vehicle according to the actual distance and the safe distance.

Abstract: Provided herein, in some embodiments, are cytosine analogs, compositions comprising cytosine analogs, and methods of use for inhibiting a Ten-eleven translocation (TET) enzyme.

Abstract: A computer-implemented method for controlling a vehicle system of a host vehicle merging into a lane. The method includes determining an actual distance between the host vehicle and the one or more remote vehicles. The actual distance is a longitudinal distance between the host vehicle and the one or more remote vehicles. The method includes determining a safe distance for merging into the lane based on a relative position of the host vehicle to the one or more remote vehicles, a speed of the host vehicle, and a speed of the one or more remote vehicles. The safe distance is a second longitudinal distance between the host vehicle and the one or more remote vehicles. The method includes controlling the vehicle system of the host vehicle to assist a merge maneuver by the host vehicle according to the actual distance and the safe distance.

Abstract: A computer-implemented method for controlling a vehicle system of a host vehicle merging with one or more remote vehicles, including receiving speed data transmitted from the one or more remote vehicles via a vehicular communication network and receiving position data of the one or more remote vehicles from the sensor system of the host vehicle that monitors an area around the host vehicle. Upon determining the one or more remote vehicles are in the area around the host vehicle based on the position data, determining a safe distance for merging into the lane based on a relative position of the host vehicle to the one or more remote vehicles. Further, controlling the vehicle system of the host vehicle according to an actual distance between the host vehicle and the one or more remote vehicles and the safe distance.

Abstract: A computer-implemented method for controlling a vehicle system of a host vehicle merging with one or more remote vehicles, including receiving speed data transmitted from the one or more remote vehicles via a vehicular communication network and receiving position data of the one or more remote vehicles from the sensor system of the host vehicle that monitors an area around the host vehicle. Upon determining the one or more remote vehicles are in the area around the host vehicle based on the position data, determining a safe distance for merging into the lane based on a relative position of the host vehicle to the one or more remote vehicles. Further, controlling the vehicle system of the host vehicle according to an actual distance between the host vehicle and the one or more remote vehicles and the safe distance.

Abstract: An automobile electronic regulator includes a timing circuit, a signal circuit, a phase shift driving circuit, a pulse oscillation outputting circuit, an electronic switching circuit, and an electronic filtering circuit. An input terminal of the electronic filtering circuit is connected to an output terminal of the electronic switching circuit, for supplying the timing circuit, the signal circuit and the phase shift driving circuit with an accurate and stable voltage. The output terminal of the signal circuit is connected to an input terminal of the phase shift driving circuit via a circuit for accelerating and limiting, for driving and amplifying a phase shift of a signal of a generated rectangular square wave. The phase shift driving circuit supplies the pulse oscillation outputting circuit with a phase shift amplification signal. The pulse oscillation outputting circuit uploads a pulse signal to an automobile-mounted inductive load system.

Abstract: An automobile electronic regulator includes a timing circuit, a signal circuit, a phase shift driving circuit, a pulse oscillation outputting circuit, an electronic switching circuit, and an electronic filtering circuit. An input terminal of the electronic filtering circuit is connected to an output terminal of the electronic switching circuit, for supplying the timing circuit, the signal circuit and the phase shift driving circuit with an accurate and stable voltage. The output terminal of the signal circuit is connected to an input terminal of the phase shift driving circuit via a circuit for accelerating and limiting, for driving and amplifying a phase shift of a signal of a generated rectangular square wave. The phase shift driving circuit supplies the pulse oscillation outputting circuit with a phase shift amplification signal. The pulse oscillation outputting circuit uploads a pulse signal to an automobile-mounted inductive load system.