Abstract: The invention provides a method for determining whether a coated contact lens is completely covered by a covalently bonded coating, comprising the steps of (1) providing a coated polyvinylalcohol-based hydrogel contact lens wherein the polyvinylalcohol-based hydrogel lens body is composed of a polymer comprising at least 50% by mole of repeating units of vinyl alcohol, comprising a lubricious coating covalently attached to the lens body, (2) contacting the coated polyvinylalcohol-based hydrogel contact lens with an aqueous solution of a hydrophilic marker polymer for obtaining a treated contact lens, the hydrophilic marker polymer having reactive groups of in which R1 is methyl or ethyl and R2 is hydrogen or a C1-C4 alkyl and a dye tag moiety, at a pH of 4.

Abstract: The invention is generally related to soft contact lenses which comprise a polyvinylalcohol-based hydrogel lens body and a durable lubricious coating thereon which are covalently attached to the polyvinylalcohol-based hydrogel lens body through 6-membered acetal rings and to a method for producing the same.

Abstract: The invention is related to a method for producing silicone hydrogel contact lenses with a stable lubricious hydrogel coating thereon providing a low surface friction. A method of the invention comprises forming a plasma-reactive hydrophilic polymer hybrid base coating having reactive functional groups on a silicone hydrogel contact lens and heating the silicone hydrogel contact lens with the hybrid base coating in an aqueous solution of a water-soluble and thermally crosslinkable hydrophilic polymeric material to form a stable lubricious hydrogel coating thereon.

Abstract: A treatment container (1) for accommodating an ophthalmic lens (2) comprises a bottom (3), a side wall (4) surrounding the bottom (3) and together with the bottom (3) forming a cavity (5) for accommodating the ophthalmic lens, a container opening (6) arranged opposite to the bottom (3), and a fluid opening (7) arranged in the bottom (3) or in the side wall (4) of the treatment container (1). The fluid opening (7) is in fluid communication with the cavity (5). The treatment container (1) further comprises a fluid conveyance channel (8) and a supply connector (9). The fluid conveyance channel (8) is connected to the fluid opening (7) so as to be in fluid communication with the fluid opening (7).

Abstract: The invention provides a method for determining whether a coated contact lens is completely covered by a covalently bonded coating, comprising the steps of (1) providing a coated polyvinylalcohol-based hydrogel contact lens wherein the polyvinylalcohol-based hydrogel lens body is composed of a polymer comprising at least 50% by mole of repeating units of vinyl alcohol, comprising a lubricious coating covalently attached to the lens body, (2) contacting the coated polyvinylalcohol-based hydrogel contact lens with an aqueous solution of a hydrophilic marker polymer for obtaining a treated contact lens, the hydrophilic marker polymer having reactive groups of in which R1 is methyl or ethyl and R2 is hydrogen or a C1-C4 alkyl and a dye tag moiety, at a pH of 4.

Abstract: Described herein is a cost-effective and time-efficient method for making UV-absorbing contact lenses. In contrast to the conventional method for making UV-absorbing contact lenses which involves copolymerizing a lens forming composition including a UV-absorbing vinylic monomer, a method of the invention involves dipping a contact lens in a solution of UV-absorbing polymer comprising carboxyl-containing monomeric units, UV-absorbing monomeric units and covalently bound radical-initiating moieties to form a UV-absorbing coating on the contact lens.

Abstract: Described herein is a cost-effective and time-efficient method for making contact lenses having a hydrophilic surface and a reduced uptake of cationic compounds, e.g. from care solutions. The method is based on conducting one of the process steps in the presence of an amino-C2-4-alkyl (meth) acrylamide or an C1-4 alkyl-amino-C2-4-alkyl (meth) acrylamide.

Abstract: The invention is related to a method for producing silicone hydrogel contact lenses with a stable lubricious hydrogel coating thereon providing a low surface friction. A method of the invention comprises forming a plasma-reactive hydrophilic polymer hybrid base coating having reactive functional groups on a silicone hydrogel contact lens and heating the silicone hydrogel contact lens with the hybrid base coating in an aqueous solution of a water-soluble and thermally crosslinkable hydrophilic polymeric material to form a stable lubricious hydrogel coating thereon.

Abstract: The invention is generally related to soft contact lenses which comprise a polyvinylalcohol-based hydrogel lens body and a durable lubricious coating thereon which are covalently attached to the polyvinylalcohol-based hydrogel lens body through 6-membered acetal rings and to a method for producing the same.

Abstract: A method of treating of a lens forming surface (2) of at least one mold half (1) of a mold for molding an ophthalmic lens, in particular of the lens forming surface of a glass mold half for molding a contact lens, especially a soft contact lens, includes the steps of: providing a plasma (10) under atmospheric pressure, and exposing the lens forming surface (2) to the plasma (10) under atmospheric pressure thereby hydrophilizing the lens forming surface (2) without depositing any material on the lens forming surface (2).

Abstract: The invention provides a method for washing, with a water-based system, reusable molds for making silicone hydrogel contact lenses. The water-based washing system comprises a solvo-surfactant which is an alkyl (propylene glycol)n ether wherein alkyl is a linear alkyl group having 2 to 5 carbon atoms and n is the integer 1, 2 or 3. The water-based system of the invention can effectively wash away silicone-containing components and other components of a lens formulation left behind on the molding surfaces of a reusable mold, after removing a silicone hydrogel contact lens cast molded in the reusable mold.

Abstract: Described herein is a cost-effective and time-efficient method for making UV-absorbing contact lenses. In contrast to the conventional method for making UV-absorbing contact lenses which involves copolymerizing a lens forming composition including a UV-absorbing vinylic monomer, a method of the invention involves dipping a contact lens in a solution of UV-absorbing polymer comprising carboxyl-containing monomeric units and UV-absorbing monomeric units to form a UV-absorbing coating on the contact lens.

Abstract: Described herein is a cost-effective and time-efficient method for making UV-absorbing contact lenses. In contrast to the conventional method for making UV-absorbing contact lenses which involves copolymerizing a lens forming composition including a UV-absorbing vinylic monomer, a method of the invention involves dipping a contact lens in a solution of UV-absorbing polymer comprising carboxyl-containing monomeric units, UV-absorbing monomeric units and covalently bound radical-initiating moieties to form a UV-absorbing coating on the contact lens.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

Abstract: The invention relates to a process for the manufacture of a hydrophilic coating on a biomedical article, which comprises treating the biomedical article for a time period of ?5 minutes with a solution of an organic solvent comprising a polyanionic compound with a number average molecular weight Mn of >5000, wherein the solution comprises less than 10% by weight of water, and wherein the solution is devoid of a cationic polymer. The coated biomedical articles obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus especially useful in the field of ophthalmic devices.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.