Patents by Inventor Harald Hubner

Harald Hubner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALPHA-2A ADRENERGIC RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20250032476
    Abstract: Described herein, inter alia, are 0.2 A adrenergic receptor agonists and uses thereof.
    Type: Application
    Filed: November 4, 2022
    Publication date: January 30, 2025
    Inventors: Brian K. Shoichet, Elissa A. Fink, Allan I. Basbaum, Joao M. Braz, Peter Gmeiner, Harald Hübner, Philipp Seemann, Tara Pfeiffer, Yang Du, Jun XU
  • BETA-ADRENERGIC RECEPTOR ALLOSTERIC MODULATORS
    Publication number: 20210353626
    Abstract: Provided herein are modulators of beta-adrenergic receptors.
    Type: Application
    Filed: April 19, 2019
    Publication date: November 18, 2021
    Inventors: Roger K. SUNAHARA, Mary J. CLARK, Brian K. KOBILKA, Cheng ZHANG, Xiangyu LIU, Peter GMEINER, Anne STÖSSEL, Harald HÜBNER, Daniela DENGLER, Markus STANEK, Brian S. SHOICHET, Magdalena KORCZYNSKA, Jacob P. MAHONEY, Jonas KAINDL
  • FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2
    Publication number: 20200308168
    Abstract: The present invention relates to fluorophenyl substituted muscarinic receptor ligands with selectivity for M3 over M2 and to the use of these compounds in the treatment of various diseases such as asthma, chronic obstructive pulmonary disease (COPD), bronchopulmonary dysplasia (BPD) and urinary incontinence.
    Type: Application
    Filed: December 3, 2018
    Publication date: October 1, 2020
    Applicants: Friedrich-Alexander-Universität Erlangen-Nürnberg, The Board of Trustees of the Leland Stanford Junior University, The Regents of the University of California
    Inventors: Ashutosh BANERJEE, Amelie BARTUSCHAT, Katrin EITEL, Peter GMEINER, Markus HEINRICH, Josefa HOFMANN, Harald HÜBNER, Hannelore RAMPP, Benjamin SCHAAKE, Brian KOBILKA, Roger SUNAHARA, Mary Joyce CLARK, Inbar FISH, Brian SHOICHET
  • Mu opioid receptor modulators
    Patent number: 10780078
    Abstract: Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: September 22, 2020
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, FRIEDRICH-ALEXANDER-UNIVERSITÄT, THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Brian K. Shoichet, Anat Levit, Aashish Manglik, Brian Kobilka, Peter Gmeiner, Harald Hübner, Daniela Gisela Dengler
  • MU OPIOID RECEPTOR MODULATORS
    Publication number: 20200109126
    Abstract: Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
    Type: Application
    Filed: January 5, 2018
    Publication date: April 9, 2020
    Inventors: Brian K. Shoichet, Peter Gmeiner, Harald Hübner, Bryan L. Roth, Daniela Gisela Dengler, Aashish Manglik, Brian Kobilka
  • MU OPIOID RECEPTOR MODULATORS
    Publication number: 20190055208
    Abstract: Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
    Type: Application
    Filed: August 17, 2018
    Publication date: February 21, 2019
    Inventors: Brian K. Shoichet, Anat Levit, Aashish Manglik, Brian Kobilka, Peter Gmeiner, Harald Hübner, Daniela Gisela Dengler
  • Phenyl Diazepane Carboxamides and Annelated Phenyl Piperazine Carboxamides Containing Oxygen and Used as Dopamine D3 Antagonists
    Publication number: 20080194539
    Abstract: The invention relates to annelated phenyl piperazine and phenyl diazepane carboxamides of general formula (I) containing oxygen. The compounds are suitable for medical use.
    Type: Application
    Filed: December 27, 2005
    Publication date: August 14, 2008
    Applicant: Schwarz Pharma AG
    Inventors: Peter Gmeiner, Harald Hubner, Karin Schlotter
  • Indolizine Carboxamides and Aza and Diaza Derivatives Thereof
    Publication number: 20080051409
    Abstract: The present invention concerns neuroreceptor-active carboxamide-substituted indolizine derivatives of general formula I wherein X represents a group of general formula X1
    Type: Application
    Filed: July 29, 2005
    Publication date: February 28, 2008
    Inventors: Peter Gmeiner, Harald Hubner, Laura Bettinetti, Karin Schlotter
  • Utilization of heteroarene carboxamide as dopamine-d3 ligands for the treatment of cns diseases
    Publication number: 20050197343
    Abstract: The invention relates to neuroreceptor active N-[(4-phenyl-1-piperazinyl)alkyl]-substituted heteroarene carboxamide of general formula (I) and to structure analogous 2-ferrocenyl compounds of general formula (II) and the utilization thereof for the treatment of CNS diseases, for example, schizophrenia, different forms of depression, neurodegenerative disorders, sexual dysfunctions, cocaine, alcohol, opiate and nicotine addiction, in addition to glaucoma, cognitive disorders, restless leg syndrome, hyperactivity syndrome (ADHS), hyperprolactinemia, hyperprolactinoma, locomotion disorders associated with Parkinson's disease, treatment of L-DOPA and neuroleptic-induced locomotion disorders, for example, akathisia, rigor, dystonia and dyskinesia, wherein the substituents are defined in the description.
    Type: Application
    Filed: July 2, 2003
    Publication date: September 8, 2005
    Inventors: Peter Gmeiner, Harald Hubner, Karin Schlotter