Abstract: The invention relates to a method and a device for the removal of a tube blank (3) located on a support core (2). The tube blank (3) is detached from the support core (2) by means of the introduction of a medium through a device (10), whereby a detachment may be alternatively or additionally achieved by the application of a vacuum to a sleeve (4) enclosing the tube blank (3).

Abstract: The present invention relates to compounds according to the general formula (1) which bind to the NR1H4 receptor and act as agonists, antagonists or mixed agonists/antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and the production of medicaments using said compounds.

Abstract: The invention provides compounds according to the general formula (1) which bind to the NR1H4 receptor and act as agonists, antagonists or mixed agonists/antagonists of the NR1H4 receptor. The invention further provides methods of treating diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.

Abstract: The present invention relates to compounds according to the general formula (I) which bind to the nuclear receptor, NR1H4, and act as agonists and antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds.

Abstract: The present invention relates to compounds according to the general formula (I) which bind to the NR1H4 receptor and act as agonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.

Abstract: The invention relates to a method and a device for the removal of a tube blank (3) located on a support core (2). The tube blank (2) is detached from the support core (2) by means of the introduction of a medium through a device (10), whereby a detachment may be alternatively or additionally achieved by the application of a vacuum to a sleeve (4) enclosing the tube blank (3).

Abstract: The invention relates to a method for producing a gene library, preferably a cDNA gene library and to a gene library that can be obtained by said method.

Abstract: The present invention relates to compounds according to the general formula (I) which bind to the nuclear receptor, NR1H4, and act as agonists and antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds.

Abstract: The present invention relates to compounds according to the general formula (I) which bind to the NR1H4 receptor and act as agonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.

Abstract: The invention provides compounds according to the general formula (1) which bind to the NR1H4 receptor and act as agonists, antagonists or mixed agonists/antagonists of the NR1H4 receptor. The invention further provides methods of treating diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.

Abstract: A method for cutting to length a strip-shaped profiled member of unvulcanized rubber material by a cutting edge includes the step of providing a speed between the cutting edge and the profiled member to be cut of at least 2.5 m/s during the cutting action. The device for carrying out the method includes a carriage and a tool with a cutting edge fastened to the carriage. The carriage has an acceleration path, defined between a rest position of the carriage and a side of the profiled member facing the carriage, of between 0.2 and 1 m. The carriage has a deceleration path, defined between an oppositely arranged side of the profiled member and an end position of the carriage, of at least 0.1 m.

Abstract: A linear drive system has a guide rail and a transport device that is moveable along the guide rail. At least one tubular, flexible hollow body is positioned along the extension of the guide rail. The hollow body consists essentially of an elastomeric material and has a first and a second end. The at least one hollow body is loadable with a pressure medium from the first or the second end. At least one squeezing roller is rotatably connected to the transport device for forcing sealingly the at least one hollow body against a counter element. The guide rail consists essentially of a flexible elastomer.