Abstract: In a method of producing an add-on part of a drive, one circuit board of multiple planar circuit boards, which have electrical conductor tracks with electrical connections, is provided with a centrally arranged opening for passage of a shaft. The circuit boards are populated with electrical and/or electronic components, and the populated electrical and/or electronic components and wiring are electrically tested. Segments made of a material with high thermal conductivity are arranged on at least two of the multiple circuit boards such that a bending process in a region of the electrical connections between the at least two circuit boards causes the segments to form an approximately peripherally closed cover. Lids are arranged on open sides of the cover to realize a closed housing arrangement.

Abstract: A drive includes a dynamoelectric rotational machine, an electronic add-on part, and a fan unit arranged axially behind one another. The fan unit generates a cooling air flow and is embodied as a two-zone fan having axial fan elements which define a first zone to generate essentially an axial air flow and include an articulated joint with an elastic region with sufficient restoring force, and radial fan blades which define a second zone that radially adjoins the first zone and generate essentially a radial air flow. Free spaces are provided at least between a housing arrangement and the fan unit and/or between the housing arrangement and a bearing shield of the dynamoelectric rotational machine and/or between the housing arrangement and/or a shaft of the dynamoelectric rotational machine, with the free spaces being acted upon during operation of the fan unit by the cooling air flow and a Venturi effect.

Abstract: A photodynamic therapy (PDT) system includes an elongated interventional device with a bundle of optical fibers forming respective light exit ports which can be individually accessed. The bundle has an optical shape sensing fiber arranged for sensing position and orientation of the light exit ports. A processor is configured to generate a light dose signal to allow generation of light outputs to the optical fibers. The light dose signal is generated in response to the determined position and orientation of the light exit ports, and three-dimensional body anatomy image information obtained by a first image modality. The processor is also configured to take image information regarding distribution of a photo sensitizer in the body tissue as input, as well as take into account image information regarding a concentration of oxygen in the body tissue.

Abstract: A therapeutic apparatus comprising: a magnetic resonance imaging system adapted for acquiring a set of magnetic resonance imaging data in an imaging zone, the magnetic resonance imaging system comprising a means for generating a magnetic field, —a guiding means adapted for guiding a beam of charged particles to a target zone within a subject, wherein the imaging zone comprises the target zone, a zone determination means adapted for determining the location of the target zone within the subject using the set of magnetic resonance imaging data, a trajectory calculation means adapted for calculating a trajectory of the beam using magnetic field data being descriptive of the magnetic field such that the calculated trajectory reaches the target zone, a control means adapted for controlling the guiding means using the calculated trajectory such that the beam follows the calculated trajectory.

Abstract: The invention relates to a temperature distribution determining apparatus for determining a temperature distribution within an object caused by applying energy to the object. A temperature distribution measuring unit (6, 7) measures a spatially and temporally dependent first temperature distribution in the object (3), while the energy is applied to the object (3) such that the object (3) is heated to a temperature within a first temperature range, and a temperature distribution estimating unit (5) estimates a spatially and temporally dependent second temperature distribution in the object (3) within a second temperature range, which is different to the first temperature range, based on the spatial and temporal dependence of the measured first temperature distribution. Since temperature distributions can be obtained not only in the first temperature range, but also in the second temperature range, the overall temperature range, in which the temperature distribution can be determined, can be increased.

Abstract: A method for colon screening and collecting data by using Magnetic Particle Imaging wherein an imaging magnetic field is generated with a spatial distribution of the magnetic field strength such that the area of examination in the colon consists of a first sub-area with lower magnetic field strength, where the magnetization of a magnetic particle which was pre-delivered to the colon is not saturated, and a second sub-area with a higher magnetic field strength, where the magnetization of said magnetic particle is saturated. The spatial location of both sub-areas in the area of examination is modified so that the magnetization of said particles changes locally. Signals are acquired and are evaluated to obtain information about the spatial distribution of the signals in the area of examination. The method may be carried out during an entire peristaltic cycle in a colon portion or segment.

Abstract: In accordance with one embodiment, a method for testing a plurality of electronic components is provided, including subdividing the plurality of electronic components into a plurality of first groups and subdividing the plurality of electronic components into a plurality of second groups. The method may further include measuring, for each first group, an electrical parameter of an interconnection of the components of the first group; measuring, for each second group, an electrical parameter of an interconnection of the components of the second group, and determining which electronic components of the plurality of electronic components have a predefined property, on the basis of the result of the measurement of the electrical parameter for the first groups and on the basis of the result of the measurement of the electrical parameter for the second groups.

Abstract: A multimodal fiducial marker for registration of multimodal data, including a first portion comprising magnetic material visible in magnetic particle imaging (MPI) data obtained by a magnetic particle imaging method and a second portion comprising a second material visible in image data obtained by another imaging method, which image data is registrable with the MPI data and a corresponding marker arrangement.

Abstract: A therapeutic apparatus for treating a subject comprising: a first heating means adapted for heating a first region of the subject, a first control means for controlling the power directed into the first region by the first heating means such that the power stays below a threshold value, a particle heating means adapted for heating magnetic nanoparticles within a second region of the subject using a time varying magnetic field, wherein the first region comprises the second region.

Abstract: The invention relates to an ingestible capsule and method for in vivo imaging and/or treatment of one or more diseased areas of interest within the gastrointestinal tract of an animal or human being.

Abstract: A Photodynamic Therapy (PDT) system with an elongated interventional device (IDV) with a bundle of optical fibers (F1, F2, F3) forming respective light exit ports which can be individually accessed. The bundle has an optical shape sensing fiber (OSS), e.g. including Fiber Bragg Gratings, arranged for sensing position and orientation (P_O) of the light exit ports. A processor executes a control algorithm which generate a light dose signal (LDS) to allow generation of light outputs (LD1, LD2, LD3) to the plurality of optical fibers (F1, F2, F3) accordingly. The control algorithm generates the light dose signal (LDS) in response to the determined position and orientation of the light exit ports (P_O), and three-dimensional body anatomy image information obtained by a first image modality (I1), e.g. X-ray, MRI, CT, ultrasound, or PET-CT. This combination allows precise application of a light dose distribution for PDT treatment of a tumor with a minimal destruction of connective tissue.

Abstract: The present invention relates to a multimodal fiducial marker (10) for registration of multimodal data, comprising a first portion (12) comprising magnetic material visible in MPI data obtained by a magnetic particle imaging method and a second portion (14) comprising a second material visible in image data obtained by another imaging method, which image data shall be registered with said MPI data. Further, the present invention relates to a marker arrangement (20).

Abstract: The invention relates to an ingestible capsule and method for in vivo imaging and/or treatment of one or more diseased areas of interest within the gastrointestinal tract of an animal or human being.

Abstract: In accordance with one embodiment, a method for testing a plurality of electronic components is provided, including subdividing the plurality of electronic components into a plurality of first groups and subdividing the plurality of electronic components into a plurality of second groups. The method may further include measuring, for each first group, an electrical parameter of an interconnection of the components of the first group; measuring, for each second group, an electrical parameter of an interconnection of the components of the second group, and determining which electronic components of the plurality of electronic components have a predefined property, on the basis of the result of the measurement of the electrical parameter for the first groups and on the basis of the result of the measurement of the electrical parameter for the second groups.

Abstract: The application relates to an ingestible capsule and method for in vivo imaging and/or treatment of one or more diseased areas of interest within the gastrointestinal tract of an animal or human being.

Abstract: A medical imaging system comprises an image data acquisition module to acquire imaging data and a motion detection module to acquire motion information. A reconstruction module reconstructs image datasets from the imaging data and with use of the motion information to correct for motion. The motion detection module is provided with a shape-sensing photonic fibre system to provide a photonic output representative of the spatial shape of the photonic fibre and an arithmetic unit to compute the motion information on the basis of the photonic output.

Abstract: The present invention relates to a method for colon screening by using Magnetic Particle Imaging comprising the steps of: (a) generating an imaging magnetic field with a spatial distribution of the magnetic field strength such that the area of examination in the colon consists of a first sub-area of the colon with lower magnetic field strength, where the magnetization of a magnetic particle which was pre-delivered to the colon is not saturated, and a second sub-area of the colon with a higher magnetic field strength, where the magnetization of said magnetic particle is saturated; (b) changing the spatial location of both sub-areas in the area of examination so that the magnetization of said particles changes locally; (c) acquiring signals that depend on the magnetization in the area of examination influenced by this change; and (d) evaluating said signals to obtain information about the spatial distribution of the signals in the area of examination.

Abstract: A therapeutic system includes a therapy module to direct a therapeutic action, e.g. focused ultrasound or RF energy to a target. An imaging module, such as a magnetic resonance examination system, generates image information of a therapy region that includes the target. By way of a motion analysis module, a motion vector field is derived from the image information of the therapy region. A control module controls the therapy module based on the motion vector field. For example, based on t the motion vector field, an accurate temperature distribution is derived from magnetic resonance signals and the motion vector field. Also magnetic resonance elastography data may be employed to improve the accuracy of the temperature distribution.

Abstract: The invention relates to a temperature distribution determining apparatus for determining a temperature distribution within an object caused by applying energy to the object. A temperature distribution measuring unit (6, 7) measures a spatially and temporally dependent first temperature distribution in the object (3), while the energy is applied to the object (3) such that the object (3) is heated to a temperature within a first temperature range, and a temperature distribution estimating unit (5) estimates a spatially and temporally dependent second temperature distribution in the object (3) within a second temperature range, which is different to the first temperature range, based on the spatial and temporal dependence of the measured first temperature distribution. Since temperature distributions can be obtained not only in the first temperature range, but also in the second temperature range, the overall temperature range, in which the temperature distribution can be determined, can be increased.

Abstract: The invention relates to a system for adapting a plurality of model meshes to a plurality of image data. The system has a registration unit for registering the plurality of model meshes with the plurality of image data on the basis of a computation of a registration transformation for transforming the plurality of model meshes, and an adaptation unit for adapting the plurality of registered model meshes to the plurality of image data on the basis of a computation of locations of mesh vertices of the plurality of model meshes. The described system is capable of reducing motion artifacts in tomographic images computed from data acquired at a plurality of different cardiac cycle phases.