Patents by Inventor Harald MARX

Harald MARX has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11964556
    Abstract: The subject matter of the invention is a battery unit (100) for a hybrid vehicle (200), with a battery housing (10) which has a front side wall (23) directed towards the front side (22) of the hybrid vehicle (200) and a rear side wall (24) directed towards the rear side of the hybrid vehicle (200), and with at least one battery module (11) which is arranged in the battery housing (10), wherein at least one fuel tank (12) is arranged in the battery housing (10).
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: April 23, 2024
    Assignee: Kautex Textron GmbH & Co. KG
    Inventors: Dirk Eulitz, Klaus Gebert, Harald Lorenz, Daniel Marx, Fabian Siggia
  • Publication number: 20210239708
    Abstract: In shotgun proteomics, generally only a fraction of peptides from a parent protein are actually detected. Because a large portion of the protein sequence is not detected, it is often impossible to determine whether the expressed protein is present in a modified, spliced, or truncated form. Provided herein are methods and systems for analyzing polypeptides which allow for the increase of the mean sequence coverage of a protein concomitant with bioinformatics analysis in order to distinguish putative proteoforms with improved amino acid resolution. Aspects of the invention include (1) a deep sequencing strategy to provide more protein sequence coverage than is typically achieved, and (2) a computational approach to view protein expression across its full length and identify regions of the protein that are potentially subject to such regulation. This technology has global utility in proteomics and will be of particular use for the analysis of biosimilar protein drug therapeutics.
    Type: Application
    Filed: April 15, 2021
    Publication date: August 5, 2021
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Joshua COON, Harald MARX
  • Publication number: 20180340941
    Abstract: In shotgun proteomics, generally only a fraction of peptides from a parent protein are actually detected. Because a large portion of the protein sequence is not detected, it is often impossible to determine whether the expressed protein is present in a modified, spliced, or truncated form. Provided herein are methods and systems for analyzing polypeptides which allow for the increase of the mean sequence coverage of a protein concomitant with bioinformatics analysis in order to distinguish putative proteoforms with improved amino acid resolution. Aspects of the invention include (1) a deep sequencing strategy to provide more protein sequence coverage than is typically achieved, and (2) a computational approach to view protein expression across its full length and identify regions of the protein that are potentially subject to such regulation. This technology has global utility in proteomics and will be of particular use for the analysis of biosimilar protein drug therapeutics.
    Type: Application
    Filed: May 24, 2018
    Publication date: November 29, 2018
    Inventors: Joshua COON, Harald MARX