Abstract: The present invention relates to 6?-sialyllactose and/or pharmaceutically acceptable salts thereof for use in the treatment of a disease selected from hearing loss and hearing loss—associated tinnitus.

Abstract: The present invention relates to 6?-sialyllactose and/or pharmaceutically acceptable salts thereof for use in the treatment of a disease selected from hearing loss and hearing loss—associated tinnitus.

Abstract: The present invention relates to a branched or unbranched free or glycosidically bound polysialic acid according to general formula (1) as given as follows poly-(?(2?8 or 2?9)Neu5Ac)n (1) wherein Neu5Ac is N-acetylneuraminic acid, and n is an integer in the range from 14 to 26 and/or pharmaceutically acceptable salts thereof, a polysaccharide composition comprising the polysialic acid (1), and the use as a medicament, particularly in the therapeutic and/or prophylactic treatment of degenerative, demyelinating and inflammatory diseases of the central nervous system, and degenerative or inflammatory retinal diseases.

Abstract: The invention relates to a screw press (1) for dewatering sludge, whereas the screw press (1) features at least one inlet opening (2) for the sludge to be dewatered, whereas the screw press (1) features a pressing assembly, with the assistance of which the sludge is able to undergo a pressing process after passing the inlet opening (2), with which the liquid (9) present in the sludge is at least partially driven out of the sludge, whereas a pressing assembly comprises a worm shaft (4) that is movable in a rotational movement with the assistance of a drive (17) and several screen elements (5) surrounding the worm shaft (4), at least in sections, during the operation of the screw press (1), whereas the screen elements (5) feature a screen surface (6) turned towards the worm shaft (4) and a support structure (7) securing the stability of the screen elements (5), whereas the pressing assembly features at least one outlet opening (8) for the liquid (9) driven out of the sludge with the assistance of the worm shaft

Abstract: An arrangement includes a robot having a robot arm that supports a device powered by supply lines. The arrangement includes at least one guide element that is fastened to the robot arm, and the supply lines are moveably held against at least one segment of the robot arm by the at least one guide element. At least one storage element is provided for receiving a supply line provision. The at least one storage element releases the supply line from the supply line provision with an increasing tensile load of the supply lines and retracts the supply line into the supply line provision with a decreasing tensile load of the supply lines.

Abstract: The present invention relates to a branched or unbranched free or glycosidically bound polysialic acid according to general formula (1) as given as follows poly-(?(2?8 or 2?9)Neu5Ac)n (1) wherein Neu5Ac is N-acetylneuraminic acid, and n is an integer in the range from 14 to 26 and/or pharmaceutically acceptable salts thereof, a polysaccharide composition comprising the polysialic acid (1), and the use as a medicament, particularly in the therapeutic and/or prophylactic treatment of degenerative, demyelinating and inflammatory diseases of the central nervous system, and degenerative or inflammatory retinal diseases.

Abstract: A method for obtaining human microglial precursor cells, comprising: (a) providing a cell population comprising neural precursor cells, wherein the cell population is obtainable from embryoid bodies differentiated from human pluripotent stem cells; (b) differentiating the cell population comprising neural precursor cells into microglial precursor cells by culturing in medium comprising a growth factor selected from the group consisting of insulin and insulin-like growth factors; (c) expanding and enriching microglial precursor cells in medium comprising a growth factor selected from the group consisting of insulin and insulin-like growth factors and 10 to 150 ng/ml GM-CSF; and (d) isolating microglial precursor cells comprising CD45-positive cells.

Abstract: The present embodiments relate to an apparatus which can be used to increase the bending strength of a tube in its connection region. The apparatus may include an adapter unit, the shape of which is matched to a cross-sectional shape of a tube end in such a manner that on the one hand the adapter unit can be fitted to a tube connection of a device instead of the tube end and on the other hand the tube end can be fitted to the adapter unit. The apparatus may also include at least one spring element made of glass fiber reinforced plastic, which is connected to the adapter unit, projects out of the adapter unit in the direction of the tube and has a termination element at the projecting end, against which termination element a fitted tube abuts when subjected to bending, so that the rigidity of the spring element increases the bending strength of the tube in the region between the adapter unit and the element.

Abstract: A guide element for a corrugated tube is formed as a ring. At least one rotating roller is integrated in the interior of the ring such that the at least one rotating roller contacts the corrugated tube when the corrugated tube is passed through the ring. The at least one rotating roller rotates with a movement of the corrugated tube using the guide element. The guide element enables low-wear control of corrugated tubes.

Abstract: Microglial precursor cells for use in the treatment of malignant neoplasms of the central nervous system. A method of treating malignant neoplasms of the central nervous system comprising administering a pharmaceutically effective amount of microglial precursor cells to a subject in need thereof.

Abstract: A method for obtaining human microglial precursor cells, comprising: (a) providing a cell population comprising neural precursor cells, wherein the cell population is obtainable from embryoid bodies differentiated from human pluripotent stem cells; (b) differentiating the cell population comprising neural precursor cells into microglial precursor cells by culturing in medium comprising a growth factor selected from the group consisting of insulin and insulin-like growth factors; (c) expanding and enriching microglial precursor cells in medium comprising a growth factor selected from the group consisting of insulin and insulin-like growth factors and 10 to 150 ng/ml GM-CSF; and (d) isolating microglial precursor cells comprising CD45-positive cells.

Abstract: A method for manufacturing an electrical conductor by applying at least one paste, in particular a thick-film paste, to a substrate by a dispensing operation, wherein the paste is applied in at least one strand.

Abstract: An arrangement includes a robot having a robot arm that supports a device powered by supply lines. The arrangement includes at least one guide element that is fastened to the robot arm, and the supply lines are moveably held against at least one segment of the robot arm by the at least one guide element. At least one storage element is provided for receiving a supply line provision. The at least one storage element releases the supply line from the supply line provision with an increasing tensile load of the supply lines and retracts the supply line into the supply line provision with a decreasing tensile load of the supply lines.

Abstract: A guide element for a corrugated tube is formed as a ring. At least one rotating roller is integrated in the interior of the ring such that the at least one rotating roller contacts the corrugated tube when the corrugated tube is passed through the ring. The at least one rotating roller rotates with a movement of the corrugated tube using the guide element. The guide element enables low-wear control of corrugated tubes.

Abstract: The present embodiments relate to an apparatus which can be used to increase the bending strength of a tube in its connection region. The apparatus may include an adapter unit, the shape of which is matched to a cross-sectional shape of a tube end in such a manner that on the one hand the adapter unit can be fitted to a tube connection of a device instead of the tube end and on the other hand the tube end can be fitted to the adapter unit. The apparatus may also include at least one spring element made of glass fiber reinforced plastic, which is connected to the adapter unit, projects out of the adapter unit in the direction of the tube and has a termination element at the projecting end, against which termination element a fitted tube abuts when subjected to bending, so that the rigidity of the spring element increases the bending strength of the tube in the region between the adapter unit and the element.

Abstract: A sensor element is described for determining a physical property of a measuring gas, in particular the pressure or the concentration of a gas component in a gas mixture, in particular in the exhaust gas of an internal combustion engine. The sensor element has an electrode exposed to the measuring gas and a reference electrode exposed to a reference gas, ambient air in particular, through a porous volume. The two electrodes are separated from one another by a solid electrolyte. To avoid premature aging of the reference electrode as a result of deposits of foreign substances contained in the reference gas or of chemical interactions caused by the foreign substances, the volume material is selected with respect to its physical and chemical properties in such a way that the foreign substances are bound in the volume and/or are subjected to a chemical reaction.

Abstract: A machine for the manufacture of a web of single-faced corrugated board comprises a nip pressure device for a liner web to be pressed against a corrugated paper web. This nip pressure device comprises a nip pressure belt which is comprised of a fabric of metal with warp threads and weft threads. The warp threads and weft threads are connected to each other at least where intersecting.

Abstract: The reference air channel of a gas sensor or a lambda probe having a laminate body produced by printing technology is provided. The laminate body is produced by printing a suitably structured layer onto a neighboring layer, for example, by screen printing.

Abstract: An electrochemical sensor, in particular for determining the oxygen content in exhaust gases of internal combustion engines, has a solid electrolyte element having at least one first electrode, at least one second electrode, and at least one heating element. The second electrode located to the heating element is connected to ground, and the first electrode coacting with the second electrode is negatively polarized, a negative operating voltage being provided.

Abstract: A planar sensor element for determining gas components, which includes a layer structure with a heating element integrated therein with a layer-shaped heating conductor. The heating conductor is arranged in a layer plane of the layer structure so that an at least approximately homogeneous distribution of the heating power of the heating element over the cross-section of the layer structure is obtained.