Abstract: A control that can be a throttle control of a handle-bared vehicle is presented. According to some embodiments, a control can include a plurality of circuit boards, each of the circuit boards including a transmission coil, sensor coils, and control circuitry the drives the transmission coil and receives signals from the sensor coils; and one or more targets mounted on a shaft and configured to rotate over the sensor coils of the plurality of circuit boards as the shaft is rotated, wherein the plurality of circuit boards are mounted around the shaft, and wherein the position of the target is determined by the control circuitry as the shaft is rotated.

Abstract: The present invention relates to a sensing composition for detecting a volatile organic compound in its gas phase, comprising 1) a silylated cellulose selected from the group of trialkylsilyl cellulose, triarylsilyl cellulose and alkylarylsilyl cellulose; and 2) a fluorescent dye. The detection of a volatile with this sensing composition comprises placing the sensing composition (optionally present as a layer on a support) in the vicinity of a potential source of a volatile and analyzing the sensing composition to determine whether a volatile of the potential source has reached the sensing composition. This detection can be performed in a quantitative manner by means of spectrophotometric analysis, and/or by image analysis of the sensing composition. The invention is particularly useful for application in high throughput screening.

Abstract: The present invention is related to production of a sterol mix in a modified yeast cell, wherein the amount of zymosterol present in said mix is dramatically reduced or abolished via modification of sterol acyltransferase activity within said yeast. The modified yeast cell can be used for production of vitamin D3 or derivatives and/or metabolites thereof.

Abstract: The present invention relates to regio- and stereoselective hydration of oleic acid derivatives, including esters of oleic acid, by action of modified oleate hydratase.

Abstract: The present invention is related to production of a sterol mix in a modified yeast cell, wherein the amount of zymosterol present in said mix is dramatically reduced or abolished via modification of sterol acyltransferase activity within said yeast. The modified yeast cell can be used for production of vitamin D3 or derivatives and/or metabolites thereof.

Abstract: The present invention is related to modified sterol acyltransferase enzymes with improved activity and/or specificity towards acylation of the vitamin D3 precursor 7-dehydrocholesterol (7-DHC) to be used in biotechnological production of vitamin D3. The invention further relates to a host strain expressing said modified enzymes and their use in a process for production of vitamin D3 or derivatives and/or metabolites thereof.

Abstract: The present disclosed subject matter relates to a housing for a firearm with an exchangeable barrel, comprising a bushing into which the barrel root of the exchangeable barrel may be inserted in the axial direction. The bushing has a slot in the axial direction and a clamping device for bringing the slot from a starting position into a narrowed position. The bushing is configured to receive the barrel root in a press-fitting manner when the slot is in the starting position and has a spreading device for bringing the slot from the starting position into an expanded position.

Abstract: The present disclosed subject matter relates to a housing for a firearm with an exchangeable barrel, comprising a bushing into which the barrel root of the exchangeable barrel may be inserted in the axial direction. The bushing has a slot in the axial direction and a clamping device for bringing the slot from a starting position into a narrowed position. The bushing is configured to receive the barrel root in a press-fitting manner when the slot is in the starting position and has a spreading device for bringing the slot from the starting position into an expanded position.

Abstract: A method for producing a gun barrel with an integrally adjoining housing for at least one breech head includes the steps of providing a cylindrical blank having a through-bore corresponding to the breech head diameter; hammering a first longitudinal portion of the blank on a part of a first hammering mandrel corresponding to the inner profile of the barrel while the first hammering mandrel is guided through the through-bore; and hammering a second longitudinal portion of the blank on a second hammering mandrel corresponding to the inner profile of the housing while the second hammering mandrel is inserted into the through-bore.

Abstract: The present invention relates to a recombinant microorganism which is capable of expressing a cytochrome P450 reductase (CPR) and, optionally, a cytochrome P450 enzyme (CYP) and which is capable of overexpressing a Ice2p comprising the amino acid sequence set out in SEQ ID NO: 2 or a sequence having at least 50% sequence identity thereto. The invention further relates to use of Ice2p to stabilize expression of a cytochrome P450 reductase in a recombinant microorganism.

Abstract: The present invention relates to a recombinant E. coli strain characterized in that the organisms contains a gene coding for a protein having esterase activity. Such E. coli is suitable for the preparation of a protein with esterase activity, whereby the expression takes place without coexpression of GroEL and/or GroES from a plasmid. The expression of glutathione reductase and/or thioredoxin reductase may be abolished by mutation. Furthermore, the ability of the organism to grow under oxygen-rich conditions has been restored by mutation. The expression of the gene of the protein with esterase activity is unaccompanied by the expression of an additional gene encoding a heat shock chaperone protein.

Abstract: A method for producing a gun barrel with an integrally adjoining housing for at least one breech head includes the steps of providing a cylindrical blank having a through-bore corresponding to the breech head diameter; hammering a first longitudinal portion of the blank on a part of a first hammering mandrel corresponding to the inner profile of the barrel whilst the first hammering mandrel is guided through the through-bore; and hammering a second longitudinal portion of the blank on a second hammering mandrel corresponding to the inner profile of the housing whilst the second hammering mandrel is inserted into the through-bore.

Abstract: A forward set trigger device for a firearm, includes a striking element that is acted upon by a main spring and has a catch interacting with a locking element, which can be disengaged from the catch by a trigger blade via a release member. The forward set trigger further includes an uncocking mechanism for the main spring by means of which a main spring support facing away from the striking element can be brought into a position that uncocks the main spring. A forward setting mechanism having a spring element, is articulated to the trigger blade and supported on a stop and which can be brought into an unstable cocked position during a forward setting movement of the trigger blade, and wherein the uncocking mechanism brings the spring element out of its unstable cocked position when the main spring support is moved into the uncocked position.

Abstract: A forward set trigger device for a firearm, includes a striking element that is acted upon by a main spring and has a catch interacting with a locking element, which can be disengaged from the catch by a trigger blade via a release member. The forward set trigger further includes an uncocking mechanism for the main spring by means of which a main spring support facing away from the striking element can be brought into a position that uncocks the main spring. A forward setting mechanism having a spring element, is articulated to the trigger blade and supported on a stop and which can be brought into an unstable cocked position during a forward setting movement of the trigger blade, and wherein the uncocking mechanism brings the spring element out of its unstable cocked position when the main spring support is moved into the uncocked position.

Abstract: The invention relates to an isolated polypeptide having esterase activity comprising an amino acid sequence shown in any one of SEQ ID NO's 2, 4, 6, 8, 10, 12 or 14 or a homologue thereof, comprising an amino acid substitution or deletion of one or more amino acids as shown in said SEQ ID NO's and resulting in a mutant polypeptide having an increased concentration of the fraction of the mutant polypeptide being present as an active and soluble protein in cleared lysate of the mutant polypeptide expressed in E. coli relative to the concentration of the fraction of the polypeptide without the mutation being present as an active and soluble protein in cleared lysate of the polypeptide without the one or more deletion or substitution expressed in E. coli under the same conditions. The invention also relates to nucleic acid encoding the polypeptides according to the invention, and the use of the polypeptides.

Abstract: The invention relates to a drop-safety mechanism for a firearm having a pivot-mounted, trigger, said trigger being designed as an arm of a double lever, the other arm of which supports a counterweight that can be displaced between a rest position and a functional position. The counterweight is resiliently pre-tensioned in the rest position and strikes on a part of the firearm in the functional position to block the trigger from unintended firing.

Abstract: Polypeptide and recombinant protein having esterase activity which exhibit the amino acid sequence SEQ. ID. No. 1 and the use thereof.

Abstract: The invention relates to a trigger mechanism for a firearm, comprising a spring-loaded firing pin which, when in the cocked position, engages on a catch. The catch can be released at a right angle to the direction of the firing pin to fire and can be displaced between the cocked position and a safety position uncocking the firing pin spring along the direction of the firing pin to lock the firearm. The catch slides on an intermediate member when displaced, said member being movable in the direction of release of the catch and engaging on a click-stop edge of a trigger, which click-stop edge can be disengaged to fire.

Abstract: The invention relates to a cocking and uncocking mechanism for a firearm, comprising a spring-loaded firing pin which, when in the cocked position, engages on a catch that can be released to fire, said catch being displaceable by an actuator element acting upon the catch via a link motion the control cam of which maintains the force to be applied to the actuator element to displace the catch to the cocked position substantially constant at least in the center region of the actuation path.

Abstract: Polypeptide and recombinant protein having esterase activity which exhibit the amino acid sequence SEQ. ID. No. 1 and the use thereof.