Patents by Inventor Harald Raethe

Harald Raethe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid peroral contraceptive preparations
    Publication number: 20070072836
    Abstract: The solid peroral contraceptive contains an effective ingredient combination of dienogest in a daily dosage of equal to or less than 2.0 mg and ethinyl estradiol in a daily dosage of less than 0.03 mg together with one or more pharmaceutically acceptable carriers. The dienogest is released in two stages, while the ethinyl estradiol is released with the first stage portion of the dienogest.
    Type: Application
    Filed: February 13, 2006
    Publication date: March 29, 2007
    Inventors: Sabine Fricke, Hagen Gericke, Ralf Ladwig, Alexander Buske, Harald Raethe
  • Solid peroral contraceptive preparations
    Publication number: 20060205701
    Abstract: The solid peroral contraceptive contains an effective ingredient combination of dienogest in a daily dosage of equal to or less than 2.0 mg and ethinyl estradiol in a daily dosage of less than 0.03 mg together with one or more pharmaceutically acceptable carriers. The dienogest is released in two stages, while the ethinyl estradiol is released with the first stage portion of the dienogest.
    Type: Application
    Filed: March 27, 2006
    Publication date: September 14, 2006
    Inventors: Sabine Fricke, Hagan Gericke, Ralf Ladwig, Alexander Buske, Harald Raethe
  • Method for isolating pharmaceutically exploitable etidronate disodium
    Patent number: 6974885
    Abstract: The method of isolating an anhydrous etidronate disodium particulate includes preparing a liquid-liquid dispersion consisting of an aqueous-organic phase and an etidronate-disodium-salt-containing aqueous phase; adjusting a temperature of the liquid-liquid dispersion to between 0 and 30° C. and intensely agitating so that a coarse-particle fraction precipitates from the liquid-liquid dispersion, then drawing off a fine-particle suspension and allowing a fine-particle fraction to precipitate from it and filtering and drying the coarse particle fraction. In a preferred embodiment the fine-particle fraction is separated from the fine-particle suspension for recycling The resulting anhydrous etidronate disodium particulate has a grain size of from about 0.1 to 1 mm and a bulk density of 0.4 to 0.6 g/cm2 with good properties for pharmaceutical applications.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: December 13, 2005
    Assignee: Schering AG
    Inventors: Detlef Grawe, Barbara Schmidt, Harald Raethe
  • Method for isolating pharmaceutically exploitable etidronate disodium
    Publication number: 20040024245
    Abstract: The invention relates to the isolation of etidronate disodium whereby
    Type: Application
    Filed: June 26, 2003
    Publication date: February 5, 2004
    Inventors: Detlef Grawe, Barbara Schmidt, Harald Raethe
  • Steroid intermediate products and method of their production
    Patent number: 5831104
    Abstract: The invention is directed to novel steroid intermediate products of general formula I ##STR1## The steroid intermediate products which can be isolated according to the invention are suitable for the synthesis of 13-ethyl-11-methylene-18,19-bisnor-17.alpha.-pregn-4-en-20-in-17-ol (desogestrel).Further, processes for producing the steroid intermediate products of general formula I are described. The olefination of the 11-oxo steroids is carried out under the influence of ultrasound.
    Type: Grant
    Filed: September 9, 1994
    Date of Patent: November 3, 1998
    Assignee: Jenapharm GmbH
    Inventors: Sven Ring, Gerhard Teichmueller, Gisela Weber, Sigfrid Schwarz, Bernd Erhart, Bernd Undeutsch, Harald Raethe, Peter Moellmann, Carmen Pfeiffer, Hans-Joachim Palme