Abstract: A device for measuring an electric field includes a micromechanical structure made of a material that is electrically conductive at an operating temperature. The micromechanical structure has a frame portion and a movable portion; the movable portion is electrically conductively and mechanically elastically connected to the frame portion and can be moved relative to the frame portion; the micromechanical structure is designed so that, when the micromechanical structure is arranged in the electric field, an electrical polarization of the micromechanical structure occurs by a first field intensity component not equal to zero and is parallel to a first direction, the electrical polarization causing a first force component acting on the movable portion parallel to the first direction and a change in the spatial arrangement of the movable portion relative to the frame portion dependent on the first force component. A detector determines the change.

Abstract: A device for measuring an electric field includes a micromechanical structure made of a material that is electrically conductive at an operating temperature. The micromechanical structure has a frame portion and a movable portion; the movable portion is electrically conductively and mechanically elastically connected to the frame portion and can be moved relative to the frame portion; the micromechanical structure is designed so that, when the micromechanical structure is arranged in the electric field, an electrical polarization of the micromechanical structure occurs by a first field intensity component not equal to zero and is parallel to a first direction, the electrical polarization causing a first force component acting on the movable portion parallel to the first direction and a change in the spatial arrangement of the movable portion relative to the frame portion dependent on the first force component. A detector determines the change.

Abstract: A hula seal as disclosed extends in a circumferential direction, a radial direction and an axial direction relative to a central axis.The hula seal includes a first leaf extending from the first edge region to the second edge region and a second leaf extending from the first edge region to the second edge region. The first leaf is the same distance as the second leaf from the central axis in the radial direction, and is adjacent to and overlaps the second leaf in the circumferential direction, when installed in a gas turbine. The first leaf is attached to the second leaf such that the first leaf can move relative to the second leaf in the circumferential direction when installed in a gas turbine.

Abstract: A hula seal as disclosed extends in a circumferential direction, a radial direction and an axial direction relative to a central axis. The hula seal includes a first leaf extending from the first edge region to the second edge region and a second leaf extending from the first edge region to the second edge region. The first leaf is the same distance as the second leaf from the central axis in the radial direction, and is adjacent to and overlaps the second leaf in the circumferential direction, when installed in a gas turbine. The first leaf is attached to the second leaf such that the first leaf can move relative to the second leaf in the circumferential direction when installed in a gas turbine.

Abstract: A new method for manufacturing a metal part with bi-metallic characteristic in an additive manufacturing process includes providing a first powder of a metal with a first thermal expansion coefficient; providing a second powder of a metal with a second thermal expansion coefficient different from the first thermal expansion coefficient; manufacturing a first pure metal layer by successively melting layers of the first powder alone; manufacturing on the first pure metal layer a mixed layer by successively melting layers of a third powder being a mixture of the first and second powders, whereby the percentage of the first powder decreases from 100% to 0% with increasing thickness of the mixed layer, and whereby the percentage of the second powder increases at the same time from 0% to 100%; and manufacturing a second pure metal layer by successively melting layers of the second powder alone.

Abstract: According to the screening method of the invention substances capable of modulating &ggr;-secretase activity are identified by incubating a source and a substrate of &ggr;-secretase activity with a test substance and detecting a C-terminal fragment released from said substrate.

Abstract: The present invention relates to a process for finding substances capable of specifically inhibiting membrane-bound proteases and a high throughput screening test for finding substances capable of specifically inhibiting &ggr;-secretase or presenilinase. The invention further relates to the use of this process or this high throughput screening test for finding substances which are specifically capable of inhibiting &ggr;-secretase or presenilinase. It also discloses substances which can be found with a process according to the invention, the use of said substances according to the invention for preparing a medicament for treating neurodegenerative disorders, particularly Alzheimer's disease, and pharmaceutical formulations containing the substances according to the invention.

Abstract: The invention relates to proteins, peptides or aspartyl-proteases comprising specified consensus motifs and nucleic acids encoding said proteins, peptides or aspartyl-proteases. The invention further relates to methods of screening for substances capable of inhibiting said aspartyl-proteases, substances identifiable with said method and pharmaceutical compositions comprising said substances.