Patents by Inventor Harald Trauthwein
Harald Trauthwein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240034715Abstract: A process for purifying ethylene cyanohydrin involves incubating an industrial grade ethylene cyanohydrin product with at least one titanium(IV)alkoxide. Ethylene cyanohydrin products with purities of >99% contain less than 0.05% of ethylene glycol (EG), and/or contain a water content of less than 1000 ppm.Type: ApplicationFiled: November 8, 2021Publication date: February 1, 2024Applicant: Evonik Operations GmbHInventors: Sebastian Bestgen, Günther Gräff, Maik Caspari, Thorben Schütz, Harald Trauthwein
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Patent number: 8686181Abstract: The present invention relates to a process for preparing ethylene glycol dimethacrylate, which comprises transesterification of ethylene glycol with an ester of methacrylic acid in the presence of catalysts, wherein a combination comprising lithium amide (LiNH2) and lithium chloride (LiCl) is used as catalyst. The process of the invention makes it possible to prepare ethylene glycol dimethacrylate particularly inexpensively and in a very high purity.Type: GrantFiled: May 8, 2008Date of Patent: April 1, 2014Assignee: Evonik Roehm GmbHInventors: Joachim Knebel, Thorben Schuetz, Guido Protzmann, Harald Trauthwein, Guenther Lauster, Thomas Kehr, Gerhard Koelbl, Guenter Westhaeuser
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Publication number: 20130172598Abstract: The present invention relates to a process for preparing ethylene glycol dimethacrylate, which comprises transesterification of ethylene glycol with an ester of methacrylic acid in the presence of catalysts, wherein a combination comprising lithium amide (LiNH2) and lithium chloride (LiCl) is used as catalyst. The process of the invention makes it possible to prepare ethylene glycol dimethacrylate particularly inexpensively and in a very high purity.Type: ApplicationFiled: May 8, 2008Publication date: July 4, 2013Applicant: Evonik Roehm GmbHInventors: Joachim Knebel, Thorben Schuetz, Guido Protzmann, Harald Trauthwein, Guenther Lauster, Thomas Kehr, Gerhard Koelbl, Guenter Westhaeuser
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Patent number: 8304223Abstract: The invention relates to novel mutants of ?PLE, to vehicles containing the same and to their use in the production of enantiomer-enriched alcohols, carboxylic acids and esters.Type: GrantFiled: March 11, 2008Date of Patent: November 6, 2012Assignee: Enzymicals AGInventors: Uwe Bornscheuer, Anke Hummel, Dominique Böttcher, Elke Brüsehaber, Kai Doderer, Harald Trauthwein
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Patent number: 8129563Abstract: The present invention relates to a process for preparing allyl methacrylate, comprising the reaction of allyl alcohol with an ester of methacrylic acid, wherein the reaction is catalyzed by zirconium acetylacetonate. The process according to the invention enables particularly favorable preparation of allyl methacrylate with a very high purity.Type: GrantFiled: May 8, 2008Date of Patent: March 6, 2012Assignee: Evonik Roehm GmbHInventors: Bardo Schmitt, Guido Protzmann, Thorben Schuetz, Harald Trauthwein, Reinhold Martin, Joachim Knebel, Ingo Sander, Klaus Gottmann, Thomas Kehr, Dieter Bathen, Christian Maul
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Patent number: 8049030Abstract: The present invention relates to a process for preparing (meth)acrylates, which comprises the transesterification of an alcohol with a low-boiling ester of (meth)acrylic acid in the presence of catalysts, with the alcohol liberated from the low-boiling ester of (meth)acrylic acid being separated off by distillation, characterized in that the molar ratio of low-boiling ester of (meth)acrylic acid to starting alcohol present in the reaction mixture is increased during the reaction by addition of low-boiling ester of (meth)acrylic acid. The process of the invention makes a particularly inexpensive preparation of (meth)acrylates having a very high purity possible.Type: GrantFiled: May 8, 2008Date of Patent: November 1, 2011Assignee: Evonik Röhm GmbHInventors: Guido Protzmann, Harald Trauthwein, Joachim Knebel, Thorben Schuetz, Gerhard Koelbl, Thomas Kehr, Guenther Lauster
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Patent number: 8039664Abstract: The present invention relates to a process for preparing butanediol dimethacrylates, which comprises the transesterification of butanediol with an ester of methacrylic acid in the presence of catalysts, wherein a combination comprising at least one lithium compound and at least one calcium compound is used as catalyst, at least one of the compounds of lithium and/or of calcium is an oxide, a hydroxide, an alkoxide having from 1 to 4 carbon atoms or a carboxylate having from 1 to 4 carbon atoms and at least part of the reaction is carried out in the presence of an effective amount of water. The process of the invention makes a particularly inexpensive preparation of butanediol dimethacrylates having a very high purity possible.Type: GrantFiled: May 8, 2008Date of Patent: October 18, 2011Assignee: Evonik Roehm GmbHInventors: Joachim Knebel, Thorben Schuetz, Harald Trauthwein, Thomas Kehr, Guenther Lauster, Guido Protzmann, Gerhard Koelbl, Guenter Westhaeuser
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Publication number: 20110207186Abstract: The invention relates to novel mutants of ?PLE, to vehicles containing the same and to their use in the production of enantiomer-enriched alcohols, carboxylic acids and esters.Type: ApplicationFiled: March 11, 2008Publication date: August 25, 2011Applicant: ENZYMICALS AGInventors: Uwe Bornscheuer, Anke Hummel, Dominique Böttcher, Elke Brüsehaber, Kai Doderer, Harald Trauthwein
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Publication number: 20100204509Abstract: The present invention relates to a process for preparing (meth)acrylates, which comprises the transesterification of an alcohol with a low-boiling ester of (meth)acrylic acid in the presence of catalysts, with the alcohol liberated from the low-boiling ester of (meth)acrylic acid being separated off by distillation, characterized in that the molar ratio of low-boiling ester of (meth)acrylic acid to starting alcohol present in the reaction mixture is increased during the reaction by addition of low-boiling ester of (meth)acrylic acid. The process of the invention makes a particularly inexpensive preparation of (meth)acrylates having a very high purity possible.Type: ApplicationFiled: May 8, 2008Publication date: August 12, 2010Applicant: EVONIK ROEHM GMBHInventors: Guido Protzmann, Harald Trauthwein, Joachim Knebel, Thorben Schuetz, Gerhard Koelbl, Thomas Kehr, Guenther Lauster
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Publication number: 20100197955Abstract: The present invention relates to a process for preparing butanediol dimethacrylates, which comprises the transesterification of butanediol with an ester of methacrylic acid in the presence of catalysts, wherein a combination comprising at least one lithium compound and at least one calcium compound is used as catalyst, at least one of the compounds of lithium and/or of calcium is an oxide, a hydroxide, an alkoxide having from 1 to 4 carbon atoms or a carboxylate having from 1 to 4 carbon atoms and at least part of the reaction is carried out in the presence of an effective amount of water. The process of the invention makes a particularly inexpensive preparation of butanediol dimethacrylates having a very high purity possible.Type: ApplicationFiled: May 8, 2008Publication date: August 5, 2010Applicant: Evonik Roehm GMBHInventors: Joachim Knebel, Thorben Schuetz, Harald Trauthwein, Thomas Kehr, Guenther Lauster, Guido Protzmann, Gerhard Koelbl, Guenter Westhaeuser
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Publication number: 20100185009Abstract: The present invention relates to a process for preparing allyl methacrylate, comprising the reaction of allyl alcohol with an ester of methacrylic acid, wherein the reaction is catalysed by zirconium acetylacetonate. The process according to the invention enables particularly favourable preparation of allyl methacrylate with a very high purity.Type: ApplicationFiled: May 8, 2008Publication date: July 22, 2010Applicant: Evonik Roehm GmbHInventors: Bardo Schmitt, Guido Protzmann, Thorben Schuetz, Harald Trauthwein, Reinhold Martin, Joachim Knebel, Ingo Sander, Klaus Gottmann, Thomas Kehr, Dieter Bathen, Christian Maul
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Patent number: 7700311Abstract: The invention relates to novel polypeptides which have the biological activity of an NAD- or NADP-dependent alcohol dehydrogenase. The invention furthermore relates to nucleic acids encoding said polypeptides, to nonhuman hosts or host cells and to reaction systems which may be used for preparing desired products. The polypeptides of the invention are preferably used in the preparation, starting from aldehydes or ketones, of primary and enantiomerically pure secondary alcohols which may serve as intermediates for medicaments. Alternatively, the polypeptides of the invention may also be employed in the reverse reaction, i.e. the oxidation of alcohols with the formation of aldehydes or ketones.Type: GrantFiled: March 10, 2005Date of Patent: April 20, 2010Assignee: Degussa AGInventors: Renate Schulze, Patrick Lorenz, Jürgen Eck, Oliver May, Harald Gröger, Harald Trauthwein
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Publication number: 20080216181Abstract: The invention relates to novel polypeptides which have the biological activity of an NAD- or NADP-dependent alcohol dehydrogenase. The invention furthermore relates to nucleic acids encoding said polypeptides, to non-human hosts or host cells and to reaction systems which may be used for preparing desired products. The polypeptides of the invention are preferably used in the preparation, starting from aldehydes or ketones, of primary and enantiomerically pure secondary alcohol's which may serve as intermediates for medicaments. Alternatively, the polypeptides of the invention may also be employed in the reverse reaction, i.e. the oxidation of alcohol's with the formation of aldehydes or ketones.Type: ApplicationFiled: March 10, 2005Publication date: September 4, 2008Applicant: Degussa AGInventors: Renate Schulze, Patrick Lorenz, Jurgen Eck, Oliver May, Harald Groger, Harald Trauthwein
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Publication number: 20070172933Abstract: The invention relates to novel amidases which can be isolated from thermophilic bacteria, in particular from thermophilic Actinomycetes, e.g. Pseudonocardia thermophila, in which the resultant amidases not only have a high temperature stability, but are also distinguished by the enantioselective reaction of a broad substrate spectrum.Type: ApplicationFiled: February 16, 2004Publication date: July 26, 2007Inventors: Ksenia Egorova, Garabed Antranikian, Harald Trauthwein, Stefan Verseck, Uwe Dingerdissen
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Patent number: 7081544Abstract: The invention relates to novel chiral ligands of formula (I), the production thereof and the use of the same in catalytic reactions.Type: GrantFiled: June 18, 2002Date of Patent: July 25, 2006Assignee: Degussa AGInventors: Matthias Beller, Kathrin Junge, Axel Monsees, Thomas Riermeier, Harald Trauthwein
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Publication number: 20050153401Abstract: A process is described for preparing optically active ?-atninocarboxylic acids from racemic N-acylated ?-aminocarboxylic acids by cnantiosclccthc hydrolysis of the N-acylated ?-aminocarboxylic acid in the presence of a hydrolase by way of biocatalyst, wherein the N-acyl substituent of the N-acylated ?-aminocarboxylic acid (I) exhibits Structure I in which R1, R2 are each selected, independently of one another, from H, halogen, alkiyl residues, OH, alkoxy residues and aryloxy residues; R3 is selected from halogen, alkoxy residues and aryloxy residues; (II) Structure IIA or IIB or the structure of the corresponding salts or (III) Structure III or the structure of the corresponding salt.Type: ApplicationFiled: March 7, 2003Publication date: July 14, 2005Inventors: Harald Groger, Harald Trauthwein, Karlheinz Drauz, Stefan Buchholz, Christiane Sacherer, Helge Werner
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Publication number: 20040249184Abstract: The invention relates to novel chiral ligands of formula (I), the production thereof and the use of the same in catalytic reactions.Type: ApplicationFiled: April 8, 2004Publication date: December 9, 2004Inventors: Matthias Beller, Kathrin Junge, Axel Monsees, Thomas Riermeier, Harald Trauthwein
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Patent number: 6573389Abstract: The present invention relates to unsymmetric bidendate organophosphorus ligands of the formula (I) which have a modular structure and have a trivalent phosphine function and a second trivalent phosphorus group which is bound via a heteroatom to a chiral ligand framework, R1R2PZC*HR3XP(YR4)(YR5) (I) where X is —O—, —S— or —NR6—, Y is a direct phosphorus-carbon bond, —O— or —NR7—, Z represents 1 to 6 carbon atoms which are joined by single or double bonds and link the phosphine unit PR1R2 to the carbon center C*, and P is trivalent phosphorus. The invention also relates to complexes comprising such a chiral ligand system of the formula (I).Type: GrantFiled: December 6, 2001Date of Patent: June 3, 2003Assignee: Degussa AGInventors: Boris E. Bosch, Harald Trauthwein, Thomas Riermeier, Uwe Dingerdissen, Axel Monsees
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Publication number: 20010047097Abstract: The invention relates to a process for the preparation of 2-arylethylamine derivates having an alkyl substituent in the 1-position, of the formula (I)Type: ApplicationFiled: May 17, 2001Publication date: November 29, 2001Inventors: Harald Trauthwein, Matthais Beller, Claudia Breindl, Christian Hartung, Annegret Tillack
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Patent number: 6297270Abstract: A process for the preparation of 2,3-dihydroindoles of the formula (I) by reaction of halostyrenes of the formula (IIa) or (IIb) with amines of the formula (III) R1—NH2 (III) in at least one inert solvent or in water, and in the presence of at least one base.Type: GrantFiled: November 18, 1999Date of Patent: October 2, 2001Assignee: Aventis Research & Technologies GmbH & Co. KGInventors: Matthias Beller, Thomas Riermeier, Harald Trauthwein, Claudia Breindl