Abstract: The invention relates to novel antibodies that bind to lymphotoxin beta receptor (LTBR) and to bispecific antigen binding molecules comprising these novel LTBR antibodies and an antigen binding domain that binds a tumor associated antigen, in particular to Fibroblast Activation Protein (FAP), to methods of producing these molecules and to methods of using the same.

Abstract: The invention relates to a shoe, in particular a sports shoe, preferably a shoe configured for fixing to a piece of sports equipment, in particular by means of a binding, such as, for example, a snowboard shoe, a ski shoe or a bicycle shoe, comprising a sole (10) and an upper (11), wherein at least one circumferential section (16) of the upper (11) adjoining the sole (10) is formed by an at least substantially inherently dimensionally stable frame and/or is formed by a maximum of four or a maximum of three or a maximum of two pieces or by only one piece.

Abstract: An ejector device is provided for food portions, and in particular for sausages. A food portion in a conveying area between two conveyor belts is engaged in a conveying mode and can be conveyed in the conveying direction. It is proposed that the ejector device has at least one adjustment mechanism for ejecting a food portion in an ejection area, which is so designed that the distance of the conveyor belts from each other in the conveying area can be partially varied. A method of ejecting food portions is also provided, in which it is proposed that the food portions be taken out of engagement with the conveyor belts as described above.

Abstract: An ejector device is provided for food portions, and in particular for sausages. A food portion in a conveying area between two conveyor belts is engaged in a conveying mode and can be conveyed in the conveying direction. It is proposed that the ejector device has at least one adjustment mechanism for ejecting a food portion in an ejection area, which is so designed that the distance of the conveyor belts from each other in the conveying area can be partially varied. A method of ejecting food portions is also provided, in which it is proposed that the food portions be taken out of engagement with the conveyor belts as described above.

Abstract: A method for contactless and non-destructive determination of the layer thicknesses of lacquer layers of vehicle parts is disclosed. In addition, the invention relates to a device to determine and measure the lacquer layers of vehicle part, the device constructed for performing optical coherence tomography and includes at least one radiation source for providing electromagnetic radiation and the electromagnetic radiation provides a wavelength (?) of 100 nm-15·103 nm and in particular 380 nm to 800 nm.

Abstract: Disclosed is an abuse-deterrent pharmaceutical composition comprising a drug with an enzyme-reactive functional group, wherein the drug has an abuse potential, and an enzyme capable of reacting with the enzyme-reactive functional group (a drug-processing enzyme), wherein the drug with the enzyme-reactive functional group is contained in the pharmaceutical composition in a storage stable, enzyme-reactive state and under conditions wherein no enzymatic activity acts on the drug.

Abstract: Disclosed are pharmaceutical compositions comprising oxycodone and an oxycodone-processing enzyme, wherein oxycodone is contained in the pharmaceutical composition in a storage stable, enzyme-reactive state and under conditions wherein no enzymatic activity acts on oxycodone.

Abstract: Disclosed are pharmaceutical compositions comprising oxycodone and an oxycodone-processing enzyme, wherein oxycodone is contained in the pharmaceutical composition in a storage stable, enzyme-reactive state and under conditions wherein no enzymatic activity acts on oxycodone.

Abstract: A method for contactless and non-destructive determination of the layer thicknesses of lacquer layers of vehicle parts is disclosed. In addition, the invention relates to a device to determine and measure the lacquer layers of vehicle part, the device constructed for performing optical coherence tomography and includes at least one radiation source for providing electromagnetic radiation and the electromagnetic radiation provides a wavelength (?) of 100 nm-15·103 nm and in particular 380 nm to 800 nm.

Abstract: Disclosed are pharmaceutical compositions comprising a drug with a laccase-reactive functional group and a laccase (EC.10.3.2) and methods for manufacturing such compositions.

Abstract: Disclosed is an abuse-deterrent pharmaceutical composition comprising a drug with an enzyme-reactive functional group, wherein the drug has an abuse potential, and an enzyme capable of reacting with the enzyme-reactive functional group (a drug-processing enzyme), wherein the drug with the enzyme-reactive functional group is contained in the pharmaceutical composition in a storage stable, enzyme-reactive state and under conditions wherein no enzymatic activity acts on the drug.

Abstract: Disclosed are pharmaceutical compositions comprising oxycodone and an oxycodone-processing enzyme, wherein oxycodone is contained in the pharmaceutical composition in a storage stable, enzyme-reactive state and under conditions wherein no enzymatic activity acts on oxycodone.

Abstract: The present invention relates to a method for the production of a particle-containing aerosol, which includes comminutating a particle-containing cylinder. These aerosols are for example particularly suitable for use in the form of an aerosol stream in a coating process. The present invention further relates to particle-containing cylinders which can be dispersed and converted into aerosol form by simple methods.

Abstract: A sole (1) for a shoe, in particular a sports shoe/hiking shoe or ski boot/snowboard boot, is proposed, with a cushioning profile (5) arranged on the outside (3) of the sole (1). The sole (1) is distinguished in that the cushioning profile (5) also extends over the inside (7) of the sole (1).

Abstract: A heart support device for pulsatile delivery of blood comprising a first and a second ventricle and a pump. Both ventricles comprises a fluid chamber and a blood-conveying chamber, wherein each fluid chamber can be filled with a fluid or emptied by way of the pump in such a way that an expansion or contraction of the fluid chamber occurs. In an expansion of the fluid chamber of a ventricle, a compression of the blood-conveying chamber of the same ventricle takes place, wherein a rigid pressure plate is disposed between a fluid chamber and the respective blood-conveying chamber, said pressure plate being able to move in the direction of the respective blood-conveying chamber.

Abstract: A heart support device for pulsatile delivery of blood comprising a first and a second ventricle and a pump. Both ventricles comprises a fluid chamber and a blood-conveying chamber, wherein each fluid chamber can be filled with a fluid or emptied by way of the pump in such a way that an expansion or contraction of the fluid chamber occurs. In an expansion of the fluid chamber of a ventricle, a compression of the blood-conveying chamber of the same ventricle takes place, wherein a rigid pressure plate is disposed between a fluid chamber and the respective blood-conveying chamber, said pressure plate being able to move in the direction of the respective blood-conveying chamber.

Abstract: A fully implantable left ventricular assist system comprising a pumping means connectable via adapter elements to the ventricle includes two compressible chambers in the form of sacs (5, 5?) and a compressing means (4) to alternatingly fill and discharge the compressible chambers (5, 5?) at the same time, including a drive unit (41) assigned thereto, a cooling means (50) for cooling the drive unit (41), and a power supply unit (60) for the drive unit (41) and cooling means (50). In this implantable system the pumping means, compression means (4), drive unit (41) and part of the cooling means (50) are accommodated in a two-part housing (1) on which tubular ports (10a, 10b; 10?a, 10?b) for connecting Y-shaped adapter elements (3, 3?) are configured.

Abstract: A method for inductively measuring the position of a metal strip is proposed, in which, at least on one side of the strip, a primary coil fed by AC voltage is arranged on one side of a strip edge and a secondary coil is arranged on the other side of the strip edge, which secondary coil measures the voltage which is induced by the primary coil and results from the coupling effect with the primary coil and the metal strip situated in between, in which, as a result of lateral relative movement between the metal strip and the primary and secondary coils, the measurement gradient that can be obtained as a result is determined and compared with a predetermined optimum measurement gradient, whereupon, in the event of a difference, the measurement gradient that has been ascertained is matched electronically to the predetermined optimum measurement gradient and the adapted values then obtained are used for the current strip movement control.

Abstract: A fully implantable left ventricular assist system comprising a pumping means connectable via adapter elements to the ventricle includes two compressible chambers in the form of sacs (5, 5′) and a compressing means (4) to alternatingly fill and discharge the compressible chambers (5, 5′) at the same time, including a drive unit (41) assigned thereto, a cooling means (50) for cooling the drive unit (41), and a power supply unit (60) for the drive unit (41) and cooling means (50).

Abstract: A segment for lining cavities, in particular tunnels, includes a substantially shell-shaped body bounded by an inner face, an outer face and side faces, with at least one opening in a side face for the purpose of receiving a dowel. The opening being configured as a substantially cylindrical bore into which projects a tube of limited deformability. A gap being provided between the outer circumference of the tube and the wall of the bore.