Patents by Inventor Haregewein Assefa

Haregewein Assefa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED TETRACYCLINE COMPOUNDS
    Publication number: 20170305840
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: December 9, 2016
    Publication date: October 26, 2017
    Inventors: Mark L. Nelson, Kwasi Ohemeng, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Y. Ismail, Oak K. Kim, Jude Mathews, Rachid Mechiche
  • Substituted tetracycline compounds for treatment of inflammatory skin disorders
    Patent number: 9481639
    Abstract: Methods and compositions for the treatment of skin disorders (e.g., acne, rosacea) are described.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: November 1, 2016
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Haregewein Assefa, Beena Bhatia, Michael P. Draper, Laura Honeyman, Oak K. Kim, Dennis P. Molnar
  • SUBSTITUTED TETRACYCLINE COMPOUNDS
    Publication number: 20150045329
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: May 19, 2014
    Publication date: February 12, 2015
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Kwasi Ohemeng, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Y. Ismail, Oak K. Kim, Jude Mathews, Rachid Mechiche
  • SUBSTITUTED TETRACYCLINE COMPOUNDS
    Publication number: 20140155357
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 5, 2014
    Inventors: Paul Abato, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Y. Ismail, Mark L. Nelson, Kwasi Ohemeng, Jingwen Pan
  • Substituted tetracycline compounds for treatment of inflammatory skin disorders
    Publication number: 20130345179
    Abstract: Methods and compositions for the treatment of skin disorders (e.g., acne, rosacea) are described.
    Type: Application
    Filed: August 19, 2013
    Publication date: December 26, 2013
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Haregewein Assefa, Beena Bhatia, Michael P. Draper, Laura Honeyman, Oak K. Kim, Dennis P. Molnar
  • Substituted tetracycline compounds for treatment of inflammatory skin disorders
    Patent number: 8513223
    Abstract: Methods and compositions for the treatment of skin disorders (e.g., acne, rosacea) are described.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: August 20, 2013
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Haregewein Assefa, Beena Bhatia, Michael P. Draper, Laura Honeyman, Oak Kim, Dennis P. Molnar
  • Substituted tetracycline compounds
    Patent number: 8466132
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: June 18, 2013
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Paul Abato, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Y. Ismail, Mark L. Nelson, Kwasi Ohemeng, Jingwen Pan
  • Substituted tetracycline compounds
    Patent number: 8318706
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: November 27, 2012
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Oak Kim, Haregewein Assefa, Laura Honeyman
  • Substituted Tetracycline Compounds
    Publication number: 20100305072
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms.
    Type: Application
    Filed: December 21, 2007
    Publication date: December 2, 2010
    Inventors: Oak K. Kim, Mark L. Nelson, Paul Abato, Haregewein Assefa, Joel Bernaiac, Mohamed Y. Ismail, Todd Bowser, Mark Grier, Beena Bhatia, Atul K. Verma, Laura Honeyman, Jingwen Pan
  • PRODRUGS OF 9-AMINOMETHYL TETRACYCLINE COMPOUNDS
    Publication number: 20100249076
    Abstract: The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them.
    Type: Application
    Filed: June 3, 2010
    Publication date: September 30, 2010
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Victor Amoo, Haregewein Assefa, Beena Bhatia, Joel Berniac, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Oak K. Kim, Rachid Mechiche, Kwasi Ohemeng, Jingwen Pan
  • Substituted Tetracycline Compounds for Treatment of Inflammatory Skin Disorders
    Publication number: 20080312193
    Abstract: Methods and compositions for the treatment of skin disorders (e.g., acne, rosacea) are described.
    Type: Application
    Filed: December 21, 2007
    Publication date: December 18, 2008
    Inventors: Haregewein Assefa, Beena Bhatia, Michael Draper, Laura Honeyman, Oak K. Kim, Dennis P. Molnar
  • Amino-methyl substituted tetracycline compounds
    Patent number: 7326696
    Abstract: Aminomethyl substituted tetracycline compounds, pharmaceutical compositions, and methods of use thereof are discussed.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: February 5, 2008
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Laura Honeyman, Mohamed Y. Ismail, Oak Kim, Rachid Mechiche, N. Laxma Reddy, Atul K. Verma, Peter Viski, Tadeusz Warchol, Ivan Yanachkov
  • Amino-methyl substituted tetracycline compounds
    Publication number: 20080015169
    Abstract: Aminomethyl substituted tetracycline compounds, pharmaceutical compositions, and methods of use thereof are discussed.
    Type: Application
    Filed: June 5, 2007
    Publication date: January 17, 2008
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Laura Honeyman, Mohamed Ismail, Oak Kim, Rachid Mechiche, N. Reddy, Atul Verma, Peter Viski, Tadeusz Warchol, Ivan Yanachkov
  • 10-substituted tetracyclines and methods of use thereof
    Publication number: 20070093455
    Abstract: 10-Substituted tetracycline compounds are described.
    Type: Application
    Filed: July 21, 2006
    Publication date: April 26, 2007
    Inventors: Paul Abato, Haregewein Assefa, Joel Berniac, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman
  • Prodrugs of 9-aminomethyl tetracycline compounds
    Publication number: 20060287283
    Abstract: The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them.
    Type: Application
    Filed: January 12, 2006
    Publication date: December 21, 2006
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Victor Amoo, Haregewein Assefa, Beena Bhatia, Joel Berniac, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Oak Kim, Rachid Mechiche, Kwasi Ohemeng, Jingwen Pan
  • Substituted tetracycline compounds
    Publication number: 20060166945
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: October 25, 2005
    Publication date: July 27, 2006
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Paul Abato, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Ismail, Mark Nelson, Kwasi Ohemeng, Jingwen Pan
  • Substituted tetracycline compounds
    Publication number: 20050143352
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: June 25, 2004
    Publication date: June 30, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark Nelson, Kwasi Ohemeng, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Ismail, Oak Kim, Jude Mathews, Rachid Mechiche
  • Prodrugs of 9-aminomethyl tetracycline compounds
    Publication number: 20050137174
    Abstract: The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them.
    Type: Application
    Filed: June 25, 2004
    Publication date: June 23, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Kwasi Ohemeng, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Oak Kim, Rachid Mechiche, Jingwen Pan
  • Amino-methyl substituted tetracycline compounds
    Publication number: 20050026875
    Abstract: Aminomethyl substituted tetracycline compounds, pharmaceutical compositions, and methods of use thereof are discussed.
    Type: Application
    Filed: December 15, 2003
    Publication date: February 3, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Laura Honeyman, Mohamed Ismail, Oak Kim, Rachid Mechiche, N. Reddy, Atul Verma, Peter Viski, Tadeusz Warchol, Ivan Yanachkov