Patents by Inventor Hariharan Periasamy

Hariharan Periasamy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted carbapenems for the treatment of bacterial infections
    Patent number: 11180504
    Abstract: This invention relates to carbapenem compounds of the following formula: wherein A, Z, X, R1, and R4 are as described herein, as well as stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bacterial infections, as well as the processes for the preparation of compounds, the pharmaceutical compositions of these compounds and their use in the treatment of bacterial infection.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: November 23, 2021
    Assignees: ORCHID PHARMA LTD., MERCK SHARP & DOHME CORP.
    Inventors: Gopalan Balasubramanian, Maneesh Paul-Satyaseela, Chidambaram Venkateswaran Srinivasan, Sridhar Ramanathan Iyer, Hariharan Periasamy, Venkatesan Parameswaran, Bharani Thirunavukkarasu, Prabhakar Rao Gunturu, Manjula Devi Deshkumar, Venkateshwarlu Jakkala, Michael Miller, Ravi P. Nargund, Sheo Singh, Shuzhi Dong, Hongwu Wang, Katherine Young
  • CARBAPENEM COMPOUNDS
    Publication number: 20200291029
    Abstract: This invention relates to carbapenem compounds, their stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bacterial infections, as well as the processes for the preparation of compounds, the pharmaceutical compositions of these compounds and their use in the treatment of bacterial infection.
    Type: Application
    Filed: March 15, 2017
    Publication date: September 17, 2020
    Inventors: Gopalan Balasubramanian, Maneesh Paul-Satyaseela, Chidambaram Venkateswaran Srinivasan, Sridhar Ramanathan Iyer, Hariharan Periasamy, Venkatesan Parameswaran, Bharani Thirunavukkarasu, Prabhakar Rao Gunturu, Manjula Devi Deshkumar, Venkateshwarlu Jakkala, Michael Miller, Ravi P. Nargund, Sheo Singh, Shuzhi Dong, Hongwu Wang, Katherine Young
  • Compounds and their use
    Patent number: 10201532
    Abstract: Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as ?-lactamase inhibitors, which restore or enhance the antibiotic spectrum of a suitable antibiotic agent. The compounds of formula (I) act as inhibitors of ?-lactamases. These compounds restore/potentiate the activities of ?-lactam antibiotics against carbapenemases. These compounds find use in diagnostic method for detecting ?-lactamases.
    Type: Grant
    Filed: November 25, 2011
    Date of Patent: February 12, 2019
    Assignee: ALLECRA THERAPEUTICS GMBH
    Inventors: Senthilkumar Udayampalayam Palanisamy, Maneesh Paul-Satyaseela, Shridhar Narayanan, Gopalan Balasubramanian, Aravind Appu, Senthilnathan Manickam, Hariharan Periasamy