Patents by Inventor Harikiran Nistala

Harikiran Nistala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment Of Hyperglycemia With Solute Carrier Family 39 Member 5 (SLC39A5) Inhibitors
    Publication number: 20250032529
    Abstract: The present disclosure provides methods of treating subjects having increased serum glucose level and/or hyperglycemia, methods of identifying subjects having an increased risk of developing increased serum glucose level and/or hyperglycemia, and methods of detecting human Solute Carrier Family 39 Member 5 variant nucleic acid molecules and variant polypeptides.
    Type: Application
    Filed: August 8, 2024
    Publication date: January 30, 2025
    Inventors: Harikiran Nistala, Cristopher Van Hout, Lyndon Mitnaul, Anthony Marcketta
  • Treatment of hyperglycemia with solute carrier family 39 member 5 (SLC39A5) inhibitors
    Patent number: 12083141
    Abstract: The present disclosure provides methods of treating subjects having increased serum glucose level and/or hyperglycemia, methods of identifying subjects having an increased risk of developing increased serum glucose level and/or hyperglycemia, and methods of detecting human Solute Carrier Family 39 Member 5 variant nucleic acid molecules and variant polypeptides.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: September 10, 2024
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Harikiran Nistala, Cristopher Van Hout, Lyndon Mitnaul, Anthony Marcketta
  • Treatment Of Hyperglycemia With Solute Carrier Family 39 Member 5 (SLC39A5) Inhibitors
    Publication number: 20200297751
    Abstract: The present disclosure provides methods of treating subjects having increased serum glucose level and/or hyperglycemia, methods of identifying subjects having an increased risk of developing increased serum glucose level and/or hyperglycemia, and methods of detecting human Solute Carrier Family 39 Member 5 variant nucleic acid molecules and variant polypeptides.
    Type: Application
    Filed: March 12, 2020
    Publication date: September 24, 2020
    Inventors: Harikiran Nistala, Cristopher Van Hout, Lyndon Mitnaul, Anthony Marcketta
  • LOSS OF FUNCTION RODENT MODEL OF SOLUTE CARRIER 39 MEMBER 5
    Publication number: 20200288683
    Abstract: This disclosure relates to a rodent model. More specifically, this disclosure relates to a loss of function of solute carrier 39 member 5 (SLC39A5) rodent model. In particular, disclosed herein are genetically modified rodent animals that carry a loss of function mutation in an endogenous Slc39a5 gene and use of such rodent animals in elucidating the role of SLC39A5 in zinc homeostasis, glycemic regulation and lipid metabolism.
    Type: Application
    Filed: March 12, 2020
    Publication date: September 17, 2020
    Inventors: Harikiran NISTALA, Aristides N. ECONOMIDES
  • Rodent model of steel syndrome
    Patent number: 10463029
    Abstract: This disclosure relates to a rodent model of Steel Syndrome. Disclosed herein are genetically modified rodent animals that carry a mutation in an endogenous rodent Col27a1 gene, equivalent to a mutation in humans causing Steel Syndrome.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: November 5, 2019
    Assignee: REGENERON PHARMACEUTICALS, INC.
    Inventors: Claudia Gonzaga-Jauregui, Chia-Jen Siao, Harikiran Nistala, Kalyan C. Nannuru