Patents by Inventor Harish Makker
Harish Makker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9421091Abstract: An intraocular lens insertion apparatus includes a hollow tube having an interior wall defining a hollow space through which an intraocular lens may be passed from the open space into an eye. A lubricity enhancing component is covalently bonded to the hollow tube at the interior wall in an amount effective to facilitate the passage of the intraocular lens through the hollow space. The lubricity enhancing component includes a substituent component effective to reduce hydrolysis of said lubricity enhancing component relative to an identical lubricity enhancing component without the substituent component.Type: GrantFiled: February 16, 2015Date of Patent: August 23, 2016Assignee: Abbott Medical Optics Inc.Inventors: Harish Makker, Can B. Hu, Michael D. Lowery
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Publication number: 20150157454Abstract: An intraocular lens insertion apparatus includes a hollow tube having an interior wall defining a hollow space through which an intraocular lens may be passed from the open space into an eye. A lubricity enhancing component is covalently bonded to the hollow tube at the interior wall in an amount effective to facilitate the passage of the intraocular lens through the hollow space. The lubricity enhancing component includes a substituent component effective to reduce hydrolysis of said lubricity enhancing component relative to an identical lubricity enhancing component without the substituent component.Type: ApplicationFiled: February 16, 2015Publication date: June 11, 2015Inventors: Harish Makker, Can B. Hu, Michael D. Lowery
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Patent number: 8956684Abstract: Apparatus, and methods of making and using apparatus, for inserting intraocular lenses (IOLs) are disclosed. The apparatus includes a hollow tube having an interior wall defining a hollow space through which an intraocular lens may be passed from the open space into an eye. A lubricity enhancing component is covalently bonded to the hollow tube at the interior wall in an amount effective to facilitate the passage of the intraocular lens through the hollow space. The lubricity enhancing component includes a substituent component effective to reduce hydrolysis of said lubricity enhancing component relative to an identical lubricity enhancing component without the substituent component.Type: GrantFiled: November 20, 2009Date of Patent: February 17, 2015Assignee: Abbott Medical Optics Inc.Inventors: Harish Makker, Can Hu, Michael D. Lowery
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Patent number: 8323799Abstract: Soft, flexible highly lubricious coatings for polymeric IOL insertion cartridges that allow IOLs to be easily inserted through small bore cartridges suitable for use with small (less than 3 mm) incisions are provided. These lubricious coatings allow IOLs to be inserted into the eye of a patient without the risk of lens damage or transfer of lubricants to the lens surface during implantation. Specifically, polymeric coatings comprising a matrix polymer having an equivalent weight greater than 5000 g/eq are used to form interpenetrating networks (IPN) on the surface of hydrophobic structural polymers. The IPNs thus formed entrap highly lubricious hydrophilic compounds within the IPN using multi-functional cross linkers.Type: GrantFiled: October 26, 2011Date of Patent: December 4, 2012Assignee: Abbott Medical Optics Inc.Inventors: Can B Hu, Michael D Lowery, Harish Makker
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Publication number: 20100129523Abstract: Apparatus, and methods of making and using apparatus, for inserting intraocular lenses (IOLs) are disclosed. The apparatus includes a hollow tube having an interior wall defining a hollow space through which an intraocular lens may be passed from the open space into an eye. A lubricity enhancing component is covalently bonded to the hollow tube at the interior wall in an amount effective to facilitate the passage of the intraocular lens through the hollow space. The lubricity enhancing component includes a substituent component effective to reduce hydrolysis of said lubricity enhancing component relative to an identical lubricity enhancing component without the substituent component.Type: ApplicationFiled: November 20, 2009Publication date: May 27, 2010Applicant: Abbot Medical Optic Inc.Inventors: Harish Makker, Can Hu, Michael D. Lowery
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Patent number: 7687097Abstract: Apparatus, and methods of making and using apparatus, for inserting intraocular lenses (IOLs) are disclosed. The apparatus includes a hollow tube having an interior wall defining a hollow space through which an intraocular lens may be passed from the open space into an eye. A lubricity enhancing component is covalently bonded to the hollow tube at the interior wall in an amount effective to facilitate the passage of the intraocular lens through the hollow space. The lubricity enhancing component includes a substituent component effective to reduce hydrolysis of said lubricity enhancing component relative to an identical lubricity enhancing component without the substituent component.Type: GrantFiled: June 7, 2005Date of Patent: March 30, 2010Assignee: Abbott Medical Optics Inc.Inventors: Harish Makker, Can B. Hu, Michael D. Lowery
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Patent number: 7632431Abstract: An intraocular lens includes an optic adapted to focus light toward a retina of an eye, and at least one fixation member configured to at least assist in supporting the optic in the eye. The fixation member includes a proximal portion coupled to the optic and a distal portion configured to be in contact with eye tissue when the intraocular lens is in use in the eye. The proximal portion of the fixation member includes at least one first area formed of a first, substantially rigid material, and at least one second area formed of a second material which is more flexible than the first material.Type: GrantFiled: December 22, 2005Date of Patent: December 15, 2009Assignee: Abbott Medical Optics Inc.Inventors: Massoud Ghazizadeh, Harish Makker
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Patent number: 7348038Abstract: Apparatus for inserting intraocular lenses (IOLs) into eyes include a hollow tube including a material and having an interior wall defining a hollow space through which an IOL is passed and an outlet through which the IOL is passed from the hollow space into an eye, and a lubricity enhancing component physically secured to said hollow tube and concentrated at or near the interior wall in an amount effective to facilitate the passage of the IOL through the hollow space.Type: GrantFiled: December 16, 2003Date of Patent: March 25, 2008Assignee: Advanced Medical Optics, Inc.Inventors: Harish Makker, Shih-Liang S. Yang, Daniel G. Brady, Robert E. Glick
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Publication number: 20070225399Abstract: Intraocular lenses comprised of an acrylic-silicone hybrid polymer are disclosed. The intraocular lenses described herein are suitable for insertion through incisions of 2 mm or less.Type: ApplicationFiled: March 27, 2006Publication date: September 27, 2007Applicant: Advanced Medical OpticsInventors: Michael Lowery, Harish Makker
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Publication number: 20070203502Abstract: Apparatus for inserting intraocular lenses (IOLs) into eyes include a hollow tube including a material and having an interior wall defining a hollow space through which an IOL is passed and an outlet through which the IOL is passed from the hollow space into an eye, and a lubricity enhancing component physically secured to said hollow tube and concentrated at or near the interior wall in an amount effective to facilitate the passage of the IOL through the hollow space.Type: ApplicationFiled: April 5, 2007Publication date: August 30, 2007Applicant: Advanced Medical Optics, Inc.Inventors: Harish Makker, Shih-Liang Yang, Daniel Brady, Robert Glick
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Publication number: 20070005135Abstract: An intraocular lens (IOL) insertion apparatus for implanting IOLs through smaller incisions. The insertion apparatus includes an insertion cartridge that receives the IOL and cooperates with a handpiece. The cartridge includes a longitudinal lumen from a loading chamber to an open distal mouth that gradually narrows in dimension. A push rod having an extremely soft tip thereon urges the IOL through the cartridge and from the open distal mouth. The soft tip is made of low-stimulus material having a minimum ultimate elongation of 400%. Because of the extremely soft material of the tip, the outside diameter of the open distal mouth can be reduced to no more than 2.0 mm, enabling passage through incisions of 2.2 mm or less. The soft tip may be a thermoplastic elastomer having a relatively high elongation and relatively low modulus at elongations of 100-300%.Type: ApplicationFiled: July 1, 2005Publication date: January 4, 2007Inventors: Harish Makker, Can Hu, Michael Lowery
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Publication number: 20060229635Abstract: Soft, flexible highly lubricious coatings for polymeric IOL insertion cartridges that allow IOLs to be easily inserted through small bore cartridges suitable for use with small (less than 3 mm) incisions are provided. These lubricious coatings allow IOLs to be inserted into the eye of a patient without the risk of lens damage or transfer of lubricants to the lens surface during implantation. Specifically, polymeric coatings comprising a matrix polymer having an equivalent weight greater than 5000 g/eq are used to form interpenetrating networks (IPN) on the surface of hydrophobic structural polymers. The IPNs thus formed entrap highly lubricious hydrophilic compounds within the IPN using multi-functional cross linkers.Type: ApplicationFiled: April 11, 2005Publication date: October 12, 2006Inventors: Can Hu, Michael Lowery, Harish Makker
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Publication number: 20060135642Abstract: Biocompatible polymers useful for making intraocular lenses are provided. The biocompatible polymers are generally composed of one or more acrylate monomers, crosslinked with at least one diacrylate ester and may include one or more additional components such as ultraviolet light and/or blue-violet light absorbing dyes. The posterior chamber IOLs made using the biocompatible polymers disclosed herein are suitable for placement in phakic or aphakic eyes and are intended for refractive correction including myopia, hyperopia, presbyopia, astigmatisms and for implantation after removal of the natural crystalline lens as warranted by medical conditions such as cataracts.Type: ApplicationFiled: November 17, 2005Publication date: June 22, 2006Applicant: Advanced Medical Optics, Inc.Inventors: Harish Makker, Massoud Ghazizadeh, Michael Lowery
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Publication number: 20060097413Abstract: An intraocular lens includes an optic adapted to focus light toward a retina of an eye, and at least one fixation member configured to at least assist in supporting the optic in the eye. The fixation member includes a proximal portion coupled to the optic and a distal portion configured to be in contact with eye tissue when the intraocular lens is in use in the eye. The proximal portion of the fixation member includes at least one first area formed of a first, substantially rigid material, and at least one second area formed of a second material which is more flexible than the first material.Type: ApplicationFiled: December 22, 2005Publication date: May 11, 2006Inventors: Massoud Ghazizadeh, Harish Makker
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Publication number: 20060004163Abstract: Biocompatible polymers useful for making anterior chamber intraocular lenses (AC-IOL) are provided. The biocompatible polymers are generally composed of one or more acrylate monomers, crosslinked with at least one diacrylate ester and may include one or more additional components such as ultraviolet light and/or blue-violate light absorbing dyes. The AC-IOLs made using the biocompatible polymers disclosed herein are suitable for placement in phakic or aphakic eyes and are intended for refractive correction including myopia, hyperopia, presbyopia and astigmatisms.Type: ApplicationFiled: September 1, 2005Publication date: January 5, 2006Applicant: Advanced Medical Optics, Inc.Inventors: Harish Makker, Michael Lowery, Can Hu
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Publication number: 20050221041Abstract: Apparatus, and methods of making and using apparatus, for inserting intraocular lenses (IOLs) are disclosed. The apparatus includes a hollow tube having an interior wall defining a hollow space through which an intraocular lens may be passed from the open space into an eye. A lubricity enhancing component is covalently bonded to the hollow tube at the interior wall in an amount effective to facilitate the passage of the intraocular lens through the hollow space. The lubricity enhancing component includes a substituent component effective to reduce hydrolysis of said lubricity enhancing component relative to an identical lubricity enhancing component without the substituent component.Type: ApplicationFiled: June 7, 2005Publication date: October 6, 2005Inventors: Harish Makker, Can Hu, Michael Lowery
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Publication number: 20050147735Abstract: A lubricous coating composition and methods for using same are provided. Specifically, a composition suitable for providing hydrophobic polymer surfaces with lubricious coatings is described wherein a polyolefin surface is reiteratively treated with hydrophilic polymer solutions and cross-linking solutions. Methods for reiterative coating polymer surfaces are also provided including methods wherein the hydrophobic polymer surface is pretreated using plasma energy.Type: ApplicationFiled: December 22, 2004Publication date: July 7, 2005Inventors: Michael Lowery, Harish Makker, Can Hu
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Publication number: 20050143751Abstract: A polymer material useful for manufacturing an intraocular lens (IOL) suitable for insertion through an IOL inserter barrel having an inner diameter of less than 3 mm is provided. Specifically, acrylic-silicone hybrids having a tensile strength of approximately 100 psi to 400 psi and a percent elongation at break of between 50% and 400% are disclosed.Type: ApplicationFiled: December 29, 2004Publication date: June 30, 2005Inventors: Harish Makker, Michael Lowery, Can Hu
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Publication number: 20040267359Abstract: Apparatus, and methods of making and using apparatus, for inserting intraocular lenses (IOLs) are disclosed. The apparatus includes a hollow tube having an interior wall defining a hollow space through which an intraocular lens may be passed from the open space into an eye. A lubricity enhancing component is covalently bonded to the hollow tube at the interior wall in an amount effective to facilitate the passage of the intraocular lens through the hollow space. The lubricity enhancing component includes a substituent component effective to reduce hydrolysis of said lubricity enhancing component relative to an identical lubricity enhancing component without the substituent component.Type: ApplicationFiled: June 27, 2003Publication date: December 30, 2004Inventors: Harish Makker, Can B. Hu, Michael D. Lowery
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Publication number: 20040153150Abstract: An intraocular lens includes an optic adapted to focus light toward a retina of an eye, and at least one fixation member configured to at least assist in supporting the optic in the eye. The fixation member includes a proximal portion coupled to the optic and a distal portion configured to be in contact with eye tissue when the intraocular lens is in use in the eye. The proximal portion of the fixation member includes at least one first area formed of a first, substantially rigid material, and at least one second area formed of a second material which is more flexible than the first material.Type: ApplicationFiled: January 30, 2003Publication date: August 5, 2004Applicant: ADVANCED MEDICAL OPTICS, INC.Inventors: Massoud Ghazizadeh, Harish Makker