Abstract: A device implementing the Bluetooth packet transmit optimization with simultaneous channel sensing may include at least one processor configured to transmit a first packet over a first channel in a first time period; perform channel sensing on a second channel in a second time period subsequent to the first time period; apply a remedial action to a transmission of a second packet based on the channel sensing; and transmit the second packet following the applied remedial action. The subject system utilizes some of the following potential remedial actions, such as 1) deferring transmission of a next Bluetooth frame, 2) increasing the packet transmission power, and/or 3) modifying a transmission packet type or packet length. A method and computer program product implementing the subject Bluetooth packet transmit optimization is also provided.