Patents by Inventor Harish Shinde

Harish Shinde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-HYDROXY-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE
    Publication number: 20240116916
    Abstract: The present invention relates to a method for preparing 2-[2-(2-chlorothiazol-5-yl)-2- hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof or enantiomerically enriched forms thereof, to 2-[2-(2-chlorothiazol-5-yl)-2-hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof or enantiomerically enriched forms thereof, and to the use thereof as intermediate in the preparation of 2,3-dihydrothiazolo[3,2-a]pyrimidinium compounds, specifically of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo [3,2-a]pyrimidin-4-ium-5-olate and enantiomerically enriched forms thereof.
    Type: Application
    Filed: January 21, 2022
    Publication date: April 11, 2024
    Inventors: Martin John McLaughlin, Christopher Koradin, Rahul Kaduskar, Harish Shinde, Roland Gotez, Guillaume Michel Jacques Garivet
  • METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE
    Publication number: 20240101575
    Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium-5-olate.
    Type: Application
    Filed: January 21, 2022
    Publication date: March 28, 2024
    Inventors: Christopher Koradin, Martin John McLaughlin, Roland Goetz, Rahul Kaduskar, Harish Shinde
  • SYNTHESIS OF POLYFLUORINATED ARYL AND HETEROARYL CARBOXAMIDES
    Publication number: 20240101516
    Abstract: The presently claimed invention relates to a process for the preparation of mono-, di-, tri-, fluoro arylamide or hetroarylamide.
    Type: Application
    Filed: January 17, 2022
    Publication date: March 28, 2024
    Inventors: Rahul Kaduskar, Kailaskumar Borate, Suyog Adhav, Saravanan Thirunavukkarasu, Harish Shinde, Roland Goetz
  • METHOD FOR PREPARING 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-OXO-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE
    Publication number: 20240101547
    Abstract: The present invention relates to a method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof, to 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof and to its use as intermediate in the preparation of 2,3-dihydrotheiazolo [3,2-a]pyrimidinium compounds, and specifically of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo [3,2-a]pyrimidin-4-ium-5-olate and enantiomerically enriched forms thereof.
    Type: Application
    Filed: January 21, 2022
    Publication date: March 28, 2024
    Inventors: Christopher Koradin, Martin John McLaughlin, Roland Goetz, Rahul Kaduskar, Harish Shinde, Guillaume Michel Jacques Garivet
  • Synchronized activation of datasets in multicloud computing environment
    Patent number: 11928131
    Abstract: Datasets can be synchronized across cloud-based computer environments using computer systems. A data map can be generated for source datasets for a plurality of computing environments, respectively, and an activation function can be determined based on the data map, for simultaneously activating a new dataset of a source system from one of the plurality of computing environments. A generation ID (identification) can be shared from the source system with one or more computing environments of the plurality of the computing environments, in response to receiving the activation function. The new dataset of the source system can be replicated across the one or more computing environments. A data synchronization trigger can be activated, using a synchronization coordinator module of the computer, and the data synchronization can be completed across the plurality of computing environments.
    Type: Grant
    Filed: September 27, 2021
    Date of Patent: March 12, 2024
    Assignee: International Business Machines Corporation
    Inventors: Sreekanth Ramakrishna Iyer, Rakesh Shinde, Ram Ravishankar, Harish Bharti, Grigorij Kaplan, Alberto Eduardo de Queiroz Dias
  • PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE
    Publication number: 20240051929
    Abstract: The present invention relates to a process for the preparation 2-chloro-1-(2-chlorothiazol-5-yl)ethanone.
    Type: Application
    Filed: September 28, 2020
    Publication date: February 15, 2024
    Inventors: Harish Shinde, Rahul Kaduskar, Christopher Koradin, Martin John McLaughlin, Roland Goetz, Sunil Khamkar
  • METHOD FOR PREPARING AN ENANTIOMERICALLY ENRICHED FORM OF 3-(2-CHLOROTHIAZOL-5-YL)-8-METHYL-7-OXO-6-PHENYL-2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM-5-OLATE
    Publication number: 20230416273
    Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium-5-olate.
    Type: Application
    Filed: January 21, 2022
    Publication date: December 28, 2023
    Inventors: Christopher Koradin, Martin John McLaughlin, Harish Shinde, Rahul Kaduskar, Ronald Goetz, Guillaaume Michel Jaques Garivet
  • PROCESS FOR THE PREPARATION OF ALPHA-ALKYL-2-(TRIFLUOROMETHYL)-BENZYL ALCOHOLS
    Publication number: 20230382831
    Abstract: The present invention relates to a process for the preparation of preparation ?-alkyl-2-(trifluoromethyl)-benzyl alcohol.
    Type: Application
    Filed: October 4, 2021
    Publication date: November 30, 2023
    Inventors: Timo Frassetto, Christiane Alznauer, Florian Vogt, Harish Shinde, Daniel Saelinger, Heinz Friedrich Sutoris
  • PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE
    Publication number: 20230322693
    Abstract: The present invention relates to a process for the preparation 2-chloro-1-(2-chlorothiazol-5-yl)ethanone.
    Type: Application
    Filed: September 28, 2021
    Publication date: October 12, 2023
    Inventors: Christopher Koradin, Harish Shinde, Martin John McLaughlin, Rahul Kaduskar, Philipp M. Staehle, Roland Goetz, Sunil Khamkar
  • PREPARATION OF SUBSTITUTED 4-(N'-HYDROXYCARBAMIMIDOYL)BENZOIC ACIDS
    Publication number: 20230183171
    Abstract: The present invention relates to a process for the preparation of substituted 4-(N?-hydroxy-carbamimidoyl)benzoic acids, which can be obtained by nitrilase catalyzed hydration of substituted terephthalonitriles of formula (II) in an aqueous medium to afford (ammonium) 4-cyanobenzoic acids (IIa). The hydration is followed by treatment of the aqueous reaction medium with hydroxylamine or a salt thereof to afford amidoximes (I).
    Type: Application
    Filed: May 20, 2021
    Publication date: June 15, 2023
    Inventors: Florian Vogt, Kailaskumar Borate, Bernd Wolf, Joachim Gebhardt, Guillaume Michel Jacques Garivet, Harish Shinde, Roland Goetz
  • PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES
    Publication number: 20230145982
    Abstract: The present invention relates to a process for the preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles of formula I, which can be obtained through reaction of amidoxime compounds of formula II with a haloacetic ester in the presence of a solvent and a base.
    Type: Application
    Filed: February 1, 2021
    Publication date: May 11, 2023
    Inventors: Florian Vogt, Kailaskumar Borate, Bernd Wolf, Christopher Koradin, Joachim Gebhardt, Roland Goetz, Harish Shinde
  • PD-CATALYZED AMINATION OF FLUORINATED ARYL CHLORIDES
    Publication number: 20230100114
    Abstract: The presently claimed invention relates to a process for the preparation of di-, tri-, or tetra fluoroarylamine by reacting polyfluorinated aryl chlorides with ammonia in the presence of a base, a metal catalyst and a ligand. Di-, tri-, tetrafluoroarylamines are valuable intermediates and find application in several areas, mainly in epoxy polymers, colorants, dyes, polyurethanes, agrochemicals and pharmaceutical active agents.
    Type: Application
    Filed: April 6, 2021
    Publication date: March 30, 2023
    Inventors: Kailaskumar Borate, Saravanan Thirunavukkarasu, Rahul Kaduskar, Harish Shinde, Roland Goetz
  • PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES
    Publication number: 20230066401
    Abstract: The present invention relates to a process for the preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles of formula (I), which can be obtained through reaction of amidoxime compounds of formula (II) with a haloacetic ester in the presence of a base.
    Type: Application
    Filed: February 1, 2021
    Publication date: March 2, 2023
    Inventors: Florian Vogt, Kailaskumar Borate, Bernd Wolf, Christopher Koradin, Roland Goetz, Harish Shinde
  • PREPARATION OF SUBSTITUTED AROMATIC CARBOXAMIDES
    Publication number: 20230028964
    Abstract: The present invention relates to a process for the preparation of substituted aromatic carboxamides of formula I, (formula I) which can be obtained through reaction of an aromatic carboxylic acid halide and an amine, whereas the process is conducted in the absence of an auxiliary base in a carboxylic acid ester as solvent.
    Type: Application
    Filed: November 25, 2020
    Publication date: January 26, 2023
    Inventors: Kailaskumar Borate, Bernd Wolf, Florian Vogt, Christopher Koradin, Roland Goetz, Harish Shinde
  • Process for Preparation of Optically Enriched Isoxazolines
    Publication number: 20210380569
    Abstract: The invention relates to a process for preparing optically enriched isoxazoline compounds of formula (I), wherein the variables are as defined in the specification, and the shown enantiomer has at least 80% ee; by oxo-Michael addition of hydroxyl amine or its salt to an enone of formula (II), wherein the variables have the meanings given for formula (I), in the presence of a catalyst of formula (III) and a base.
    Type: Application
    Filed: October 28, 2019
    Publication date: December 9, 2021
    Inventors: Roland Goetz, Michael Rack, Martin John McLaughlin, Harish Shinde, Ritesh Karalkar, Kailaskumar Borate, Karsten Koerber, Arun Narine, Nikolas Huwyler
  • Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds
    Patent number: 11124528
    Abstract: The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof, wherein the variables of compound of formula X are as defined in the claims or the description.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: September 21, 2021
    Assignee: BASF SE
    Inventors: Harish Shinde, Christopher Koradin, Joachim Dickhaut, Roland Goetz, Michael Rack, Eric George Klauber, Sukunath Narayanan, Dhanyakumar Raut
  • Process for preparing chiral 2,3-dihydrothiazolo[3,2-A] pyrimidin-4-ium compounds
    Patent number: 11034703
    Abstract: The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof, wherein the variables of compound of formula X are as defined in the claims and the description.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: June 15, 2021
    Assignee: BASF SE
    Inventors: Harish Shinde, Christopher Koradin, Joachim Dickhaut, Roland Goetz, Eric George Klauber, Sukunath Narayanan, Dhanyakumar Raut
  • PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS
    Publication number: 20210087207
    Abstract: The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof, wherein the variables of compound of formula X are as defined in the claims and the description.
    Type: Application
    Filed: May 2, 2018
    Publication date: March 25, 2021
    Inventors: Harish SHINDE, Christopher KORADIN, Joachim DICKHAUT, Roland GOETZ, Eric George KLAUBER, Sukunath NARAYANAN, Dhanyakumar RAUT
  • Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds
    Publication number: 20200055872
    Abstract: The present invention relates to a process for preparing optically active compounds of formula X and intermediates thereof, wherein the variables of compound of formula X are as defined in the claims or the description.
    Type: Application
    Filed: April 25, 2018
    Publication date: February 20, 2020
    Inventors: Harish SHINDE, Christopher KORADIN, Joachim DICKHAUT, Roland GOETZ, Michael RACK, Eric George KLAUBER, Sukunath NARAYANAN, Dhanyakumar RAUT
  • Substituted pyrimidinium compounds for combating animal pests
    Patent number: 10149477
    Abstract: Substituted pyrimidinium compounds of the general formula (I): wherein the compounds are useful for controlling invertebrate pests.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: December 11, 2018
    Assignee: BASF SE
    Inventors: Joachim Dickhaut, Arun Narine, Wolfgang von Deyn, Raffael Koller, Jean-Yves Wach, Devendra Vyas, Ashokkumar Adisechan, Harish Shinde