Abstract: Systems and methods analyze a plant comprising trichomes. The system can include a back-end computer system communicably couplable to an imaging device. The imaging device captures multiple images of the plant at a plurality of different focal distances, combines the multiple images into a composite image having a greater depth of field utilizing focal stacking, and transmits the composite image to the back-end computer system. The back-end computer system identifies the trichomes imaged within the composite image utilizing a machine learning system, determines a property of the identified trichomes, determines a projected harvest time for the plant according to the property, and provides the projected harvest time to a user. The trichomes within the composite image can be identified utilizing a machine learning system.