Patents by Inventor Harlan N. Bradford

Harlan N. Bradford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calpain-inhibiting peptide analogs of the kininogen heavy chain
    Patent number: 5770693
    Abstract: Synthetic peptide analogs of human kininogen are provided which are conformationally restricted by means of intramolecular bonding. The peptides mimic the biological activity of human kininogen by inhibiting the activity of the biologically significant protease, calpain. The peptides are designed by means of an equilibrium conformational model of the kininogen heavy chain.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 23, 1998
    Assignee: Temple University-Of The Commonwealth System of Higher Education
    Inventors: Robert W. Colman, Harlan N. Bradford, Bradford A. Jameson
  • Calpain-inhibiting peptide analogs of the kininogen heavy chain
    Patent number: 5663294
    Abstract: Synthetic peptide analogs of human kininogen are provided which are conformationally restricted by means of intramolecular bonding. The peptides mimic the biological activity of human kininogen by inhibiting the activity of the biologically significant protease, calpain. The peptides are designed by means of an equilibrium conformational model of the kininogen heavy chain.
    Type: Grant
    Filed: February 7, 1995
    Date of Patent: September 2, 1997
    Assignee: Temple University of the Commonwealth System of Higher Education
    Inventors: Robert W. Colman, Harlan N. Bradford, Bradford A. Jameson