Patents by Inventor Harma Ellens

Harma Ellens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotide and polypeptide sequences encoding murine organic anion transporter 5 (mOATP5)
    Patent number: 6420544
    Abstract: Mouse OATP5 polypeptides and polynucleotides and method for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds which either agonize or antagonize mouse OATP5. Such compounds are expected to be useful in treatment of human diseases, including, but not limited to: cancer, inflammation, cardiovascular disease, central nervous system disorders, auto-immune disease, and kidney and liver disease.
    Type: Grant
    Filed: May 17, 2000
    Date of Patent: July 16, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Harma Ellens, John Feild, Lin Yue
  • Polynucleotide and polypeptide sequences encoding rat mdr1a and screening methods thereof
    Publication number: 20020055128
    Abstract: Rat mdr1a polypeptides and polynucleotides and method for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds which either agonize or antagonize rat mdr1a. Further disclosed is method for performing a selection screen, whereby compounds are discovered that neither agonize nor antagonize rat mdr1a.
    Type: Application
    Filed: January 25, 2001
    Publication date: May 9, 2002
    Inventors: Kimberly Anne Brun, Richard James Chenery, Harma Ellens, John Anthony Feild, Lin Yue
  • Polynucleotide and polypeptide sequences encoding rat mdr1b2 and screening methods thereof
    Patent number: 6169166
    Abstract: Rat mdr1b2 polypeptides and polynucleotides and method for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds which either agonize or antagonize rat mdr1b2. Further disclosed is method for performing a selection screen, whereby compounds are discovered that neither agonize nor antagonize rat mdr1b2.
    Type: Grant
    Filed: November 29, 1999
    Date of Patent: January 2, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Kimberly A. Brun, Richard J Chenery, Harma Ellens, John A Feild, Lin Yue
  • Polynucleotide and polypeptide sequences encoding rat mdr1b2 and screening methods thereof
    Patent number: 6025160
    Abstract: Rat mdr1b2 polypeptides and polynucleotides and method for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for screening for compounds which either agonize or antagonize rat mdr1b2. Further disclosed is method for performing a selection screen, whereby compounds are discovered that neither agonize nor antagonize rat mdr1b2.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: February 15, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Kimberly A Brun, Richard J Chenery, Harma Ellens, John A Feild, Lin Yue