Patents by Inventor Harmon Hoffman, Jr.

Harmon Hoffman, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug delivery collagen-impregnated synthetic vascular graft
    Patent number: 5197977
    Abstract: A collagen impregnated vascular graft including drug materials complexed with the collagen to be released slowly from the graft following implant. The graft is a porous synthetic vascular graft substrate having collagen fixed to the graft substrate and cross-linking the collagen in situ to render the porous substrate blood-tight. The drug materials complexed with the collagen fibrils may include antithrombic agents, antibacterial, antimicrobial agents, antifungal agents and the like.
    Type: Grant
    Filed: April 30, 1992
    Date of Patent: March 30, 1993
    Assignee: Meadox Medicals, Inc.
    Inventors: Harmon Hoffman, Jr., Kemal Schankereli, Milos Chvapil
  • Collagen-impregnated dacron graft
    Patent number: 5108424
    Abstract: A collagen-impregnated vascular graft includes a porous synthetic vascular graft substrate formed by knitting or weaving with at least three applications of dispersed collagen fibrils. Plasticizers are incorporated into the collagen slurry before application and the slurry is applied in separate treatments by massage and flow through techniques, cross-linked by exposure to formaldhyde vapor and dried.
    Type: Grant
    Filed: January 28, 1991
    Date of Patent: April 28, 1992
    Assignee: Meadox Medicals, Inc.
    Inventors: Harmon Hoffman, Jr., Kemal Schankereli
  • Method for forming impregnated synthetic vascular grafts
    Patent number: 4842575
    Abstract: A collagen impregnated synthetic vascular graft including a synthetic vascular graft substrate and cross-linked collagen fibril is formed by depositing an aqueous slurry of collagen fibrils in the lumen of the graft and massaging to insure intimate mixing of the fibrils into the porous structure of the substrate. After massaging, the collagen is dried and cross-linked. Repeated applications and massaging and drying further reduce porosity of the graft.
    Type: Grant
    Filed: August 5, 1988
    Date of Patent: June 27, 1989
    Assignee: Meadox Medicals, Inc.
    Inventors: Harmon Hoffman, Jr., Kemal Schankereli