Patents by Inventor Harmon Lawrence REMMEL

Harmon Lawrence REMMEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240000849
    Abstract: This invention relates to methods and compositions for detecting, identifying and treating glaucoma diseases. More particularly, this invention discloses compositions and methods for affecting intraocular pressure and increasing ocular outflows in glaucoma. Compositions and methods provided include purified and synthesized extracellular vesicle complexes from glaucoma ocular humor for use in methods and devices for detecting, characterizing and treating glaucoma diseases along with active agents. The presence of extracellular vesicle complexes in glaucoma can also be used as a biomarker.
    Type: Application
    Filed: July 11, 2023
    Publication date: January 4, 2024
    Inventors: John T. G. PENA, James Murray MITCHELL, Harmon Lawrence REMMEL
  • Patent number: 11752175
    Abstract: This invention relates to methods and compositions for detecting, identifying and treating glaucoma diseases. More particularly, this invention discloses compositions and methods for affecting intraocular pressure and increasing ocular outflows in glaucoma. Compositions and methods provided include purified and synthesized extracellular vesicle complexes from glaucoma ocular humor for use in methods and devices for detecting, characterizing and treating glaucoma diseases along with active agents. The presence of extracellular vesicle complexes in glaucoma can also be used as a biomarker.
    Type: Grant
    Filed: September 21, 2019
    Date of Patent: September 12, 2023
    Assignee: Cornell University
    Inventors: John T. G. Pena, James Murray Mitchell, Harmon Lawrence Remmel
  • Publication number: 20230174581
    Abstract: This invention relates to methods and compositions for treating diseases of intraocular pressure. More particularly, this invention discloses a range of compounds, devices and methods for detecting and/or affecting intraocular pressure, treating glaucoma diseases, and increasing ocular outflows. Compositions of this disclosure can be used for reducing ocular extracellular complexes.
    Type: Application
    Filed: September 23, 2022
    Publication date: June 8, 2023
    Applicant: AUFBAU MEDICAL INNOVATIONS LIMITED
    Inventors: John T. G. PENA, James Murray MITCHELL, Melissa A. MORGAN, Harmon Lawrence REMMEL
  • Publication number: 20230090884
    Abstract: Devices, methods and systems are provided for isolating extracellular matrix bodies. More particularly, this invention discloses devices, methods and systems for isolating extracellular matrix bodies from a biological sample for use in diagnosis and prognosis of a subject. A device may have restriction channels for isolating extracellular matrix bodies and uniform flow channels for precise pressure measurements.
    Type: Application
    Filed: September 23, 2022
    Publication date: March 23, 2023
    Applicant: AUFBAU MEDICAL INNOVATIONS LIMITED
    Inventors: John T. G. PENA, James Murray MITCHELL, Luca D'AGOSTINO, Sangeetha Tandalam PALANIVELU, Kunihiro URYU, Harmon Lawrence REMMEL
  • Publication number: 20220211800
    Abstract: This invention relates to methods and compositions for detecting, identifying and treating glaucoma diseases. In addition, this invention discloses compositions and methods for affecting intraocular pressure and increasing ocular outflows in glaucoma. Compositions are provided for treating a glaucoma disease, reducing intraocular pressure, and/or reducing ocular extracellular vesicle complexes in a subject.
    Type: Application
    Filed: March 16, 2022
    Publication date: July 7, 2022
    Applicants: CORNELL UNIVERSITY, AUFBAU MEDICAL INNOVATIONS LIMITED
    Inventors: John T. G. PENA, James Murray MITCHELL, Harmon Lawrence REMMEL
  • Publication number: 20200121724
    Abstract: This invention relates to methods and compositions for detecting, identifying and treating glaucoma diseases. More particularly, this invention discloses compositions and methods for affecting intraocular pressure and increasing ocular outflows in glaucoma. Compositions and methods provided include purified and synthesized extracellular vesicle complexes from glaucoma ocular humor for use in methods and devices for detecting, characterizing and treating glaucoma diseases along with active agents. The presence of extracellular vesicle complexes in glaucoma can also be used as a biomarker.
    Type: Application
    Filed: September 21, 2019
    Publication date: April 23, 2020
    Inventors: John T. G. PENA, James Murray MITCHELL, Harmon Lawrence REMMEL