Patents by Inventor Harold A. Ames

Harold A. Ames has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DISCOVERY OF NOVEL MOLECULES AND REPURPOSED DRUGS FOR RAS FAMILY GTPases
    Publication number: 20210041441
    Abstract: The present invention is directed to compounds, compositions and methods for modulating RAS family GTPases, in particular KRas, HRas and NRas GTPases. These GTPases are upregulated in cancer and in other tissue and represent appropriate targets for therapy. Methods for identifying the activity of compounds with respect to these and other GTPases in multiplex flow cytometry systems represents another aspect of this invention.
    Type: Application
    Filed: March 8, 2019
    Publication date: February 11, 2021
    Inventors: Larry A. Sklar, Tudor I. Oprea, Anna Waller, Angela Wandinger-Ness, Mark K. Haynes, Sharon Campbell, Harold A. Ames