Patents by Inventor Harold C. Box

Harold C. Box has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for measurement of oxidative DNA damage
    Patent number: 5906918
    Abstract: A method is provided for detecting and quantitating a DNA base modification in a sample of DNA, wherein the method involves an endonuclease digestion step, a labeling step, and a chromatographic separation step. Utilized in the method are compositions including a carrier for the DNA base modification, an internal standard, and a carrier for the internal standard. Also provided are methods for synthesizing the compositions, and kits containing the compositions.
    Type: Grant
    Filed: February 7, 1997
    Date of Patent: May 25, 1999
    Assignee: Health Research Inc.
    Inventors: Harold C. Box, Alexander E. Maccubbin, Edwin E. Budzinski, Herbert Iijima