Patents by Inventor Harold David Gunn
Harold David Gunn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9320788Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of an immune response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, such as whole killed bacterial cells, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora or exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions.Type: GrantFiled: June 20, 2013Date of Patent: April 26, 2016Assignee: Qu Biologics Inc.Inventor: Harold David Gunn
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Patent number: 9320787Abstract: The invention provides in part methods for treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The compositions may for example include killed or attenuated microbial pathogens, such as whole killed bacterial cells, and may be administered at sites distant from the cancer, for example the skin. In selected embodiments, the invention provides methods for treating a cancer situated in the colon, using formulations of E. coli cells. The administration of the immunogenic compositions may be repeated relatively frequently over a relatively long period of time. In embodiments for intradermal or subcutaneous injection, dosages may be adjusted so that injections reproduce a consistent, visible, inflammatory immune reaction at the site of administration.Type: GrantFiled: May 14, 2013Date of Patent: April 26, 2016Assignee: Qu Biologics Inc.Inventor: Harold David Gunn
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Publication number: 20150343050Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated.Type: ApplicationFiled: July 15, 2015Publication date: December 3, 2015Inventor: Harold David Gunn
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Publication number: 20150238589Abstract: The invention provides methods of treating inflammation in a specific organ or tissue of an individual. The method involves determining whether the individual has previously been infected with at least one pathogen that is pathogenic in the specific organ or tissue; and administering to the individual an anti-inflammatory composition comprising antigenic determinants, the antigenic determinants selected or formulated so that together they are specific for the at least one pathogen. The pathogen may be an endogenous or exogenous pathogen, and may further be a bacterial pathogen, a viral pathogen, a fungal pathogen, a protozoan pathogen, or a helminth pathogen.Type: ApplicationFiled: February 26, 2015Publication date: August 27, 2015Inventors: Harold David Gunn, Salim Dhanji, Brett Anthony Premack, Michael Tak Huai Chow
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Patent number: 9107864Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated.Type: GrantFiled: February 1, 2011Date of Patent: August 18, 2015Assignee: Qu Biologics Inc.Inventor: Harold David Gunn
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Patent number: 8980279Abstract: The invention provides methods of treating inflammation in a specific organ or tissue of an individual. The method involves determining whether the individual has previously been infected with at least one pathogen that is pathogenic in the specific organ or tissue; and administering to the individual an anti-inflammatory composition comprising antigenic determinants, the antigenic determinants selected or formulated so that together they are specific for the at least one pathogen. The pathogen may be an endogenous or exogenous pathogen, and may further be a bacterial pathogen, a viral pathogen, a fungal pathogen, a protozoan pathogen, or a helminth pathogen.Type: GrantFiled: July 27, 2012Date of Patent: March 17, 2015Assignee: Qu BiologicsInventors: Harold David Gunn, Salim Dhanji, Brett Anthony Premack, Michael Tak Huai Chow
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Publication number: 20140010844Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of an immune response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, such as whole killed bacterial cells, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. In alternative embodiments, exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions.Type: ApplicationFiled: June 20, 2013Publication date: January 9, 2014Inventor: Harold David Gunn
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Publication number: 20130337012Abstract: The invention provides in part methods for treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The compositions may for example include killed or attenuated microbial pathogens, such as whole killed bacterial cells, and may be administered at sites distant from the cancer, for example the skin. In selected embodiments, the invention provides methods for treating a cancer situated in the colon, using formulations of E. coli cells. The administration of the immunogenic compositions may be repeated relatively frequently over a relatively long period of time. In embodiments for intradermal or subcutaneous injection, dosages may be adjusted so that injections reproduce a consistent, visible, inflammatory immune reaction at the site of administration.Type: ApplicationFiled: May 14, 2013Publication date: December 19, 2013Applicant: Qu Biologics Inc.Inventor: Harold David Gunn
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Patent number: 8501198Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of an immune response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, such as whole killed bacterial cells, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. In alternative embodiments, exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions.Type: GrantFiled: July 26, 2010Date of Patent: August 6, 2013Assignee: Qu Biologics Inc.Inventor: Harold David Gunn
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Publication number: 20130177593Abstract: The invention provides methods of treating inflammation in a specific organ or tissue of an individual. The method involves determining whether the individual has previously been infected with at least one pathogen that is pathogenic in the specific organ or tissue; and administering to the individual an anti-inflammatory composition comprising antigenic determinants, the antigenic determinants selected or formulated so that together they are specific for the at least one pathogen. The pathogen may be an endogenous or exogenous pathogen, and may further be a bacterial pathogen, a viral pathogen, a fungal pathogen, a protozoan pathogen, or a helminth pathogen.Type: ApplicationFiled: July 27, 2012Publication date: July 11, 2013Inventors: Harold David Gunn, Salim Dhanji, Brett Anthony Premack, Michael Tak Huai Chow
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Publication number: 20120258135Abstract: The invention provides methods of formulating an anti-inflammatory composition for treating inflammatory conditions in a specific organ or tissue. The method involves selecting at least one pathogen that is pathogenic in the specific organ or tissue; producing an antigenic composition comprising antigenic determinants that together are specific for the pathogen; and formulating the antigenic composition for administration as an anti-inflammatory composition capable of eliciting an anti-inflammatory response in the specific organ or tissue. In embodiments of the invention the pathogen may be an endogenous pathogen, such as an endogenous bacterial pathogen. The pathogen may be an exogenous pathogen, such as a bacterial pathogen, viral pathogen, a fungal pathogen, or a helminth pathogen.Type: ApplicationFiled: January 26, 2012Publication date: October 11, 2012Inventors: Harold David Gunn, Salim Dhanji, Brett Anthony Premack, Michael Tak Huai Chow
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Patent number: 8034359Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of a treatment response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. In alternative embodiments, exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions.Type: GrantFiled: September 19, 2008Date of Patent: October 11, 2011Assignee: Qu Biologics Inc.Inventor: Harold David Gunn
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Publication number: 20110195093Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated.Type: ApplicationFiled: February 1, 2011Publication date: August 11, 2011Inventor: Harold David Gunn
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Patent number: 7921361Abstract: In one aspect, a method, apparatus, computer-readable medium and system is provided for facilitating user text generation and entry. In some illustrative embodiments, user input received from a digital keyboard and search list is used to retrieve completion candidates likely intended by the user or containing at least a portion of the user's intended text. Completion candidates may be selected using a pointing device (for example, a touch-sensitive screen) with a pointing operation that includes a gesture. A completion candidate may be used to search for more relevant completion candidates.Type: GrantFiled: October 12, 2007Date of Patent: April 5, 2011Assignee: 602531 British Columbia Ltd.Inventors: Harold David Gunn, John Chapman
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Publication number: 20110020401Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of an immune response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, such as whole killed bacterial cells, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. In alternative embodiments, exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions.Type: ApplicationFiled: July 26, 2010Publication date: January 27, 2011Inventor: Harold David GUNN
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Publication number: 20110010655Abstract: In one aspect of the present invention a user can rapidly enter and search for data, such as text, using a data entry system by entering one or more characters on a digital keyboard with a pointing device. With the digital keyboard the user can create words, phrases and other character sequences. As the user enters a character sequence, a mechanism for character prediction visually informs the user of which set of characters on the digital keyboard are most likely to have the character that the user wishes to next enter as part of the text. In another aspect of the present invention, as the user forms a character sequence (partial text entry), the character sequence is used to search a dictionary for a set of completion candidates that begin with the character sequence. The data entry system retrieves completion candidates from the dictionary by determining which completion candidates in the dictionary are more likely to be the ones that the user is attempting to type.Type: ApplicationFiled: March 29, 2010Publication date: January 13, 2011Applicant: 602531 British Columbia Ltd.Inventors: Mark Dostie, Harold David Gunn, Jiang Hong, Peter Knaven, William Trueman Davis
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Patent number: 7716579Abstract: A method, system and computer-readable media for supporting text entry on a personal computing device by activating automated searching to search for completion candidates which are based on a partial text entry received from a user. The completion candidates are displayed in a search list. The user may select a completion candidate from among the completion candidates in the search list to correspondingly modify the partial text entry, or the user may decline all of the completion candidates displayed in the search list and terminate the automated searching. The system may further provide a digital keyboard for use in entering text.Type: GrantFiled: May 19, 2005Date of Patent: May 11, 2010Assignee: 602531 British Columbia Ltd.Inventors: Harold David Gunn, John Chapman
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Patent number: 7681124Abstract: In one aspect, the user can rapidly enter and search for text using a data entry system through a combination of entering one or more characters on a digitally displayed keyboard with a pointing device and using a search list to obtain a list of completion candidates. The user can activate the search list to obtain a list of completion candidates at any time while entering a partial text entry with the data entry system. When the search list is active, a list of completion candidates is displayed on a graphical user interface for the user to select from and the user can perform one of several actions. When the user deactivates the search list, the user can continue adding to or modifying the current partial text entry being entered, and may re-invoke the search list to further search for completion candidates based on the modified partial text entry.Type: GrantFiled: May 19, 2005Date of Patent: March 16, 2010Assignee: 602531 British Columbia Ltd.Inventors: Harold David Gunn, John Chapman
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Publication number: 20090074816Abstract: The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of a treatment response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. In alternative embodiments, exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions.Type: ApplicationFiled: September 19, 2008Publication date: March 19, 2009Inventor: Harold David Gunn
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Patent number: 7293231Abstract: In one aspect of the invention, the user can rapidly enter and search for text through a combination of entering one or more characters (a partial text entry) on a digitally displayed keyboard with a pointing device and using a search list to display a list of selectable completion candidates based on the partial text entry. The user can select one of the completion candidates in the search list to replace the partial text entry which the user is currently entering. Alternatively, the user can select a completion candidate to be the basis of a search for a refined list of completion candidates. The user can also deactivate the interactive search list, and immediately continue adding to or modifying the current partial text entry, and may re-invoke the search list to further search for completion candidates based on the modified partial text entry.Type: GrantFiled: August 1, 2000Date of Patent: November 6, 2007Assignee: British Columbia Ltd.Inventors: Harold David Gunn, John Chapman