Abstract: A drug delivery device includes a housing, a drug delivery assembly disposed within the housing along a longitudinal axis, and a cap defining a shell. At least one electronic component, a power source, and a switch assembly are at least partially disposed in and coupled to the cap. The switch assembly is movable along a plane orthogonal to the longitudinal axis of the drug delivery assembly to cause the power source to provide power to the electronic component. The device further includes an activation mechanism at least partially disposed in the cap. Upon urging the cap along the longitudinal axis in a direction away from the housing, the activation mechanism engages the switch assembly and causes the switch assembly to move, thereby causing the power source to provide power to the at least one electronic component.

Abstract: Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.

Abstract: Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.

Abstract: Disclosed is a transport incubator capable of housing and maintaining a neonate in a controlled environment while being transported for medical care. The incubator comprises straps to secure the neonate, a battery-operated heater, a fan to circulate the warmed air, a source of humidity and at least one portable oxygen bottle. Capable of being worn by a user like a backpack, the incubator is portable and is useful for transport through difficult terrain. After making contact with a designated transport vehicle, the incubator can be disengaged from the backpack and mounted to a housing platform in the transport vehicle, the platform comprising a suspension system to minimize vibrations on the neonate. It is contemplated that the incubator system can accommodate an AC-powered battery during vehicular transport of the neonate to a medical care facility. A control unit displays data relevant to the controlled environment of the incubator and the neonate.