Patents by Inventor Harold Edgar Van Wart

Harold Edgar Van Wart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human aggrecanase and nucleic acid compositions encoding the same
    Patent number: 7094591
    Abstract: Human aggrecanase and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting aggrecanase activity in a host and methods of treating disease conditions associated with aggrecanase activity, e.g. rheumatoid arthritis, osteo-arthritis, infectious arthritis, gouty arthritis, psoriatic arthritis, spondolysis, sports injury, joint trauma, pulmonary disease, fibrosis, and the like.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: August 22, 2006
    Assignee: Syntex (U.S.A.) LLC
    Inventors: John David Allard, Renu Anand Heller, Paul Klonowski, Harold Edgar Van Wart
  • Peptidic procollagen C-proteinase inhibitors
    Patent number: 6951918
    Abstract: This invention relates to compounds of Formula (I) wherein R1-R7, A, Z and n are as described in the Summary of the Invention that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for their preparation.
    Type: Grant
    Filed: February 7, 2002
    Date of Patent: October 4, 2005
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Sharon Marie Dankwardt, Harold Edgar Van Wart, Keith Adrian Murray Walker
  • Peptidic procollagen C-proteinase inhibitors
    Publication number: 20020169133
    Abstract: This invention relates to compounds of Formula (I) 1
    Type: Application
    Filed: February 7, 2002
    Publication date: November 14, 2002
    Inventors: Sharon Marie Dankwardt, Harold Edgar Van Wart, Keith Adrian Murray Walker
  • Peptidic procollagen C-proteinase inhibitors
    Patent number: 6426402
    Abstract: This invention relates to compounds of Formula (I) wherein R1-R7, A, Z and n are as described in the Summary of the Invention that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for their preparation.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: July 30, 2002
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Sharon Marie Dankwardt, Harold Edgar Van Wart, Keith Adrian Murray Walker