Abstract: A method of treating or preventing viral infections, in particular rhinovirus infections comprising the administration of an effective amount of a 2-phenyltetralin derivative or a heterocyclic analogue thereof. Pharmaceutical compositions containing these compounds, and some novel compounds are also disclosed.

Abstract: 2-Pyridyl chroman and derivatives thereof have been discovered to have potent anti-viral activities, i.e. particular against rhinovirus. Novel compounds and their pharmaceutically acceptable salts, pharmaceutical formulations containing the compounds of this invention and the treatment of viral infections with these formulations are all disclosed. 2-(3-Pyridyl)chroman and 6-chloro-2-(3-pyridyl)chroman are examples of especially active compounds of this invention.

Abstract: Novel compounds of formula (IID) ##STR1## wherein either both X and Y represent groups independently selected from amino and lower alkylamino, or one of X and Y represents a group selected from amino and lower alkylamino and the other of X and Y represents a hydrogen atom have been found to be active against rhinoviruses and other viruses. Processes for producing these compounds include reduction of flavanone derivatives or of flavenes. Alternatively, reductive cyclization of chalcones affords the compounds. These may also be prepared by condensation of o-(substituted methyl)phenols with styrene derivatives.Pharmaceutical formulations and methods for the administration of the compounds are described.

Abstract: A method of treating or preventing viral infections, in particular rhinovirus infections comprising the administration of an effective amount of a flavan derivative of formula (I). ##STR1## Pharmaceutical compositions containing these compounds, and some novel compounds are also disclosed.

Abstract: Certain tricyclic sulphone compounds each of which is substituted in the 1-,2-,3- or 4-position by a carboxyl or (5-tetrazolyl) group and each of which is optionally substituted in the 5-,6-,7- or 8-position by a second carboxyl or (5-tetrazolyl) group or a substituent selected from cyano, halogen, nitro, alkyl, alkoxy, acyl, amino, acylamino, thioalkyl, alkylsulphinyl and alkylsulphonyl, as well as salts, and optionally substituted esters and amides of the carboxyl substituted compounds and alkyl derivatives of the tetrazolyl substituted compounds, are useful for the relief or prophylaxis of allergic conditions.

Abstract: Certain tricyclic sulphone compounds each of which is substituted in the 1-, 2-, 3- or 4-position by a carboxyl or (5-tetrazolyl) group and each of which is optionally substituted in the 5-, 6-, 7- or 8-position by a second carboxyl or (5-tetrazolyl) group or a substituent selected from cyano, halogen, nitro, alkyl, alkoxy, acyl, amino, acylamino, thioalkyl, alkylsulphinyl and alkylsulphonyl, as well as salts, and optionally substituted esters and amides of the carboxyl substituted compounds and alkyl derivatives of the tetrazolyl substituted compounds, are useful for the relief or prophylaxis of allergic conditions.