Abstract: The present invention relates to novel topical compositions for treating burns, grazes, erythema, eczema, herpes infection, evulsion, sores and any skin damage leading to sloughing, including at least three components, namely a first barrier gel, a second barrier gel and an active principle having proteolytic activity. The novel compositions have enhanced pain-killing, protective, débrding and anti-inflammatory effects relative to the conventional products used in the art.