Abstract: This invention relates to lipopolysaccharide-protein conjugate vaccines with appropriate presentation of conserved inner core oligosaccharide epitopes having improved immunogenic properties. These are based upon antigenic, detoxified bacterial lipopolysaccharides which optimally present an inner core oligosaccharide epitope following removal of at least a glycosidic phosphate of the lipid A region. These partially or completely dephosphorylated antigenic, detoxified bacterial lipopolysaccharides are linkable to an immunologically acceptable carrier and can be used in polyvalent or multivalent vaccines.

Abstract: A device for holding a plurality of rolls of wrapping material and for cutting a selected depth of wrapping material pulled from a selected roll, comprising a housing having a front, a back and opposite side walls, and a rack between the side walls of the housing for holding the rolls of wrapping material with the rolls extending generally horizontally between the side walls, each roll being rotatable on the rack about an axis extending longitudinally of the roll. The rack is mounted for rotation relative to the housing on a generally horizontal axis for moving a selected roll or wrapping material into a dispensing position adjacent the front of the housing. A cutter extends generally horizontally at the front of the housing for cutting a length of wrapping material pulled from a selected roll in the dispensing position.