Patents by Inventor Harold Kluender

Harold Kluender has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8133995
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: March 13, 2012
    Assignee: Bayer HealthCare LLC
    Inventors: Julie Dixon, Steven Magnuson, Barton Phillips, Yamin Wang, Tandy Li, Kyle Parcella, Jason Newcom, Harold Kluender, Zhenqiu Hong, Brent Chandler, Zhonghua Zhang, Kristen Allegue, Zheng Liu
  • Publication number: 20100063038
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: December 1, 2006
    Publication date: March 11, 2010
    Inventors: Julie Dixon, Barton Phillips, Furahi Achebe, Harold Kluender, Jason Newcom, Kyle Parcella, Stephen J. O'Connor, Steven Magnuson, Zhenqui Hong, Zhonghua Zhang, Zheng Liu, Uday Khire, Lei Wang, Martin Michels, Brent Chandler
  • Publication number: 20090281079
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Application
    Filed: November 30, 2006
    Publication date: November 12, 2009
    Applicant: BAYER HEALTHCARE LLV
    Inventors: Julie Dixon, Steven Magnuson, Barton Phillips, Yamin Wang, Tandy Li, Kyle Parcella, Jason Newcom, Harold Kluender, Zhenqiu Hong, Brent Chandler, Zhonghua Zhang, Kristen Allegue, Zheng Liu
  • Publication number: 20070208013
    Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
    Type: Application
    Filed: June 3, 2005
    Publication date: September 6, 2007
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Julie Dixon, Catherine Brennan, Karl Miranda, Brent Chandler, Barton Phillips, Jianmei Fan, Michael Brands, Andrea Mcclure, Benjamin Jones, Wenlang Fu, Donald Bierer, Steven Magnuson, Harold Kluender
  • Publication number: 20060122215
    Abstract: This invention relates to 1,5,6,7-tetrahydropynolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
    Type: Application
    Filed: January 18, 2006
    Publication date: June 8, 2006
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Stephen O'Connor, Wai Wong, Soongyu Choi, Harold Kluender, Jianmei Fan, Zhonghua Zhang, Rico Lavoie, Brent Podlogar
  • Publication number: 20060063760
    Abstract: This invention relates to a compound of Formula (I) and its use in treating hyper-proliferative disorders.
    Type: Application
    Filed: April 16, 2004
    Publication date: March 23, 2006
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Yamin Wang, Maio Dai, Holia Hatoum-Mokdad, Zhengqiu Hong, Harold Kluender, Gaetan Ladouceur, Tindy Li, Derek Lowe, Eric Mull, Tatiana Shelekhin, Roger Smith, Wai Wong
  • Publication number: 20050256167
    Abstract: This invention relates to substituted imidazole derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
    Type: Application
    Filed: May 20, 2005
    Publication date: November 17, 2005
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Roger Smith, Stephen O'Connor, Stephan-Nicholas Wirtz, Wai Wong, Soongyu Choi, Harold Kluender, Ning Su, Gan Wang, Furahi Achebe, Shihong Ying
  • Publication number: 20050019424
    Abstract: The invention relates generally to the use of certain substituted fused or unfused pyridazine or pyridine derivatives which are KDR inhibitors in combination with other chemotherapeutic agents for use in treatment of diseases associated with abnormal angiogenesis and/or hyperpermeability and/or hyperproliferative diseases, such as cancer.
    Type: Application
    Filed: December 20, 2002
    Publication date: January 27, 2005
    Inventors: Paul Adams, Stephen Boyer, Jacques Dumas, James Elting, Harold Kluender