Patents by Inventor Harold M. Weintraub

Harold M. Weintraub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neurogenic differentiation (neurod) genes
    Patent number: 5695995
    Abstract: Neurogenic differentiation genes and proteins are identified, isolated, and sequenced. Expression of neuroD has been demonstrated in neural, pancreatic, and gastrointestinal cells. Ectopic expression of neuroD in non-neuronal cells of Xenopus embryos induced formation of neurons.
    Type: Grant
    Filed: November 2, 1995
    Date of Patent: December 9, 1997
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Harold M. Weintraub, deceased, Jacqueline E. Lee, Stanley M. Hollenberg, Stephen J. Tapscott
  • Myod regulatory region
    Patent number: 5352595
    Abstract: Isolated DNA or RNA molecules capable of hybridizing under stringent conditions to the myoD regulatory region, its proximal promoter and distal enhancer regulatory regions, and regulatory elements within the proximal and distal regions for binding basic helix-loop-helix proteins, MyoD, and proteins binding at SP1, AP1, CAAT, M-CAT, CArG, and MEF sites in DNA. DNA or RNA expression vectors for introducing a gene into a cell under the regulatory control of the myoD regulatory region. Transduced or transfected pre-muscle cells, myocytes, or myoblasts. Methods of inducing a muscle phenotype in a non-muscle cell, positively selecting for a cells expressing MyoD, and negatively selecting for cells expressing MyoD.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: October 4, 1994
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Stephen J. Tapscott, Harold M. Weintraub, Theodore D. Palmer