Patents by Inventor Harold S. Wilkinson

Harold S. Wilkinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid Forms Comprising(-)-O-Desmethylvenlafaxine And Uses Thereof
    Publication number: 20160355457
    Abstract: Solid forms comprising a compound useful in the treatment, prevention and management of various conditions and diseases are provided herein. In particular, the invention provides solid forms comprising (?)-O-desmethylvenlafaxine, including salts thereof, having utility for the treatment, prevention and management of conditions and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: May 25, 2016
    Publication date: December 8, 2016
    Inventors: Michael Sizensky, Harold S. Wilkinson, John R. Snoonian, Norman Kim, Sharon M. Laughlin, Roger P. Bakale, Kevin Plunkett, Patrick Mousaw
  • Solid forms comprising (-)-O-desmethylvenlafaxine and uses thereof
    Publication number: 20090005457
    Abstract: Solid forms comprising a compound useful in the treatment, prevention and management of various conditions and diseases are provided herein. In particular, the invention provides solid forms comprising (?)—O-desmethylvenlafaxine, including salts thereof, having utility for the treatment, prevention and management of conditions and disorders including, but not limited to, affective disorders such as depression, bipolar and manic disorders, attention deficit disorder, attention deficit disorder with hyperactivity, Parkinson's disease, epilepsy, cerebral function disorders, obesity and weight gain, incontinence, dementia and related disorders.
    Type: Application
    Filed: February 21, 2008
    Publication date: January 1, 2009
    Inventors: Michael Sizensky, Harold S. Wilkinson, John Snoonian, Norman Kim, Sharon M. Laughlin, Roger P. Bakale, Kevin Plunkett, Patrick Mousou
  • Method of resolving amlodipine racemate
    Patent number: 6822099
    Abstract: The invention relates to methods of resolving racemic amlodipine into enantiomerically enriched compositions by precipitation with tartaric acid in the presence of a non-aqueous solvent, such as N,N′-dimethylacetamide. The molar ratio of tartaric acid:amlodipine is preferably less than 0.25:1.0 or greater than 0.75:1.0.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: November 23, 2004
    Assignee: Sepracor, Inc.
    Inventors: Chris H. Senanayake, Gerald J. Tanoury, Harold S. Wilkinson, Roger P. Bakale, Andrei A. Zlota
  • Method of resolving amlodipine racemate
    Publication number: 20030130321
    Abstract: The invention relates to methods of resolving racemic amlodipine into enantiomerically enriched compositions by precipitation with tartaric acid in the presence of a non-aqueous solvent, such as N,N′-dimethylacetamide. The molar ratio of tartaric acid:amlodipine is preferably less than 0.25:1.0 or greater than 0.75:1.0.
    Type: Application
    Filed: December 20, 2002
    Publication date: July 10, 2003
    Applicant: Sepracor, Inc.
    Inventors: Chris H. Senanayake, Gerald J. Tanoury, Harold S. Wilkinson, Roger P. Bakale, Andrei A. Zlota