Patents by Inventor Harout DerSimonian

Harout DerSimonian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOSUPPRESSANT EXTRACTS DERIVED FROM MILLETTIA LAURENTII OR PSEUDOTSUGA PINACEAE
    Publication number: 20130142895
    Abstract: One aspect of the present invention generally relates to deriving immunosuppressant extracts from Millettia laurentii or Pseudotsuga pinaceae. In addition, the present invention relates to methods of using immunosuppressant extracts of Millettia laurentii or Pseudotsuga pinaceae to treat an autoimmune condition, transplant rejection, or cancer.
    Type: Application
    Filed: March 1, 2011
    Publication date: June 6, 2013
    Applicant: NatCure Sciences, Inc.
    Inventor: Harout Dersimonian
  • Injection system
    Publication number: 20040191225
    Abstract: Novel methods of injecting agents including cells into organs, tissues, or tumors using a side release needle and, optionally, a carrier that aids in retention of the cells at the injection site, or a tissue sealant or film to seal the injection site are provided. The use of side release needles and, optionally, a carrier, sealant, or film prevents the leakage of the injected agent back out of the injection site. Agents which may be injected using the inventive method include drugs, small molecules, peptides, proteins, polynucleotides, viruses, cells, etc. Any type of cells including myoblasts may be used in the invention. The cells may be injected into any organ including the heart, brain, pancreas, liver, etc. These injection methods may find use in tissue engineering, gene therapy, and tissue/organ repair. Kits with the side release needles used in carrying out the present invention are also provided.
    Type: Application
    Filed: August 6, 2003
    Publication date: September 30, 2004
    Inventors: Jonathan H. Dinsmore, Douglas B. Jacoby, Harout DerSimonian
  • Transgenic swine & swine cells having human HLA genes
    Patent number: 6558663
    Abstract: Methods of promoting tolerance and inhibiting NK cell mediated attack in a human recipient to a swine graft are disclosed The methods include introducing into the recipient a swine hematopoietic stem cell which has been transformed with a transgene encoding a human MHC class I protein that inhibits recipient NK cell mediated attack.
    Type: Grant
    Filed: December 8, 1999
    Date of Patent: May 6, 2003
    Assignee: The General Hospital Corporation
    Inventors: Joerg Seebach, David H. Sachs, Harout DerSimonian, Christian LeGuern
  • Tolerance to natural antibody antigens
    Publication number: 20020114787
    Abstract: Methods of inducing tolerance in a recipient mammal to an antigen or to a graft which expresses the antigen. The methods typically include providing a cell from the recipient mammal which presents the antigen, and allowing the cell to produce or display the moiety in the recipient mammal, thereby inducing tolerance to the antigen.
    Type: Application
    Filed: July 16, 2001
    Publication date: August 22, 2002
    Inventors: John J. Iacomini, Harout Dersimonian, David H. Sachs
  • Transgenic swine and swine cells having human HLA genes
    Patent number: 6030833
    Abstract: A genetically engineered swine cell having a transgene encoding a human HLA protein.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: February 29, 2000
    Assignee: The General Hospital
    Inventors: Joerg Seebach, David H. Sachs, Harout DerSimonian, Christian LeGuern