Patents by Inventor Harprit S. Pannu

Harprit S. Pannu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Receptor Tyrosine Kinase Signaling Pathway Analysis For Diagnosis And Therapy
    Publication number: 20090011440
    Abstract: The invention provides a method for determining the activation status of receptor tyrosine kinase (RTK) pathways in either cell samples or patient samples by measuring receptor dimerization and relative amounts of protein-protein complexes or activated effector proteins that are characteristic of an RTK pathway. The invention also provides a method of using such status information to select patients responsive to pathway-specific drugs, and more particularly, to methods for measuring ErbB receptors and receptor complexes and using such information to select patients responsive to ErbB pathway-specific drugs. Preferably, methods of the invention are implemented by using sets of binding compounds having releasable molecular tags that are specific for multiple components of one or more complexes formed in RTK activation. After binding, molecular tags are released and separated from the assay mixture for analysis.
    Type: Application
    Filed: July 21, 2008
    Publication date: January 8, 2009
    Applicant: MONOGRAM BIOSCIENCES, INC.
    Inventors: Ali Mukherjee, Mengxiang Tang, Harprit S. Pannu, Po-Ying Chan-Hui, Sharat Singh
  • Receptor tyrosine kinase signaling pathway analysis for diagnosis and therapy
    Patent number: 7402399
    Abstract: The invention provides a method for determining the activation status of receptor tyrosine kinase (RTK) pathways in either cell samples or patient samples by measuring receptor dimerization and relative amounts of protein-protein complexes or activated effector proteins that are characteristic of an RTK pathway. The invention also provides a method of using such status information to select patients responsive to pathway-specific drugs, and more particularly, to methods for measuring ErbB receptors and receptor complexes and using such information to select patients responsive to ErbB pathway-specific drugs. Preferably, methods of the invention are implemented by using sets of binding compounds having releasable molecular tags that are specific for multiple components of one or more complexes formed in RTK activation. After binding, molecular tags are released and separated from the assay mixture for analysis.
    Type: Grant
    Filed: October 13, 2004
    Date of Patent: July 22, 2008
    Assignee: Monogram BioSciences, Inc.
    Inventors: Ali Mukherjeei, Mengxiang Tang, Harprit S. Pannu, Po-Ying Chan-Hui, Sharat Singh