Abstract: The present disclosure concerns a refractometer including a measurement window inside a flow channel of the flow vessel of the refractometer, the flow channel being designed to allow process fluid flow at least at the measurement window in laminar flow regime of the dedicated process liquid.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: An arrangement and method are disclosed for inserting and removing a head of a measuring device to and from a process space. The arrangement includes a measuring device with a measuring head and a retractor tool connected to a valve member. The retractor tool includes rails, a cradle for receiving the measuring device and arranged to slide along the rails, and a driving mechanism for moving the cradle. A valve lock mechanism prevents opening of the valve member if the measuring device is not at a location barring a fluid flow from the process space, and the head of the measuring device is insertable to the process space when the measuring device is received in the cradle.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: A sealing arrangement and method of a measuring device are disclosed, the measuring device having one or more measuring elements that have a surface in contact with a fluid being measured, a fluid chamber for the fluid being measured, and a seal to seal the joint between the fluid chamber and the measuring element. Flow channels have been formed in the measuring device to lead the rinsing fluid in contact with the seal.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: An optical measuring device including a measuring head, an inner shell including a light transmitter and a light receiver, an outer shell including a measurement orifice in one end and a fastening flange part in another end, the inner shell is arranged at least partially in the outer shell, the measuring head is arranged in the outer shell and attached to the measurement orifice from its first end and to an end of the inner shell from its second end, a gasket is arranged between the measuring head and the measurement orifice, and inside the outer shell is arranged a fluid flow path extending from the gasket towards the fastening flange part, wherein to the outer shell is formed a leak detection port having one end opening into the fluid flow path and another end opening into a side surface of the outer wall in the fastening flange part wherein a fastening flange protrudes between the opening into the side surface and the measurement orifice.

Abstract: An arrangement and method are disclosed for inserting and removing a head of a measuring device to and from a process space. The arrangement includes a measuring device with a measuring head and a retractor tool connected to a valve member. The retractor tool includes rails, a cradle for receiving the measuring device and arranged to slide along the rails, and a driving mechanism for moving the cradle. A valve lock mechanism prevents opening of the valve member if the measuring device is not at a location barring a fluid flow from the process space, and the head of the measuring device is insertable to the process space when the measuring device is received in the cradle.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: A sealing arrangement and method of a measuring device are disclosed, the measuring device having one or more measuring elements that have a surface in contact with a fluid being measured, a fluid chamber for the fluid being measured, and a seal to seal the joint between the fluid chamber and the measuring element. Flow channels have been formed in the measuring device to lead the rinsing fluid in contact with the seal.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: Compounds of formula I, wherein A, B, X, Z and R1-R6, are as defined in the claims, exhibit TRPA 1 activity and are thus useful as TRPA1 modulators.

Abstract: Compounds of formula I, wherein A, B, X, Z and R1-R6, are as defined in the claims, exhibit TRPA 1 activity and are thus useful as TRPA1 modulators.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.

Abstract: Compounds of formula (I) or (II) wherein Rx, Rz, R9, R10, R14, R14?, R15, R15?, A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.

Abstract: Compounds of formula (I) or (II) wherein Rx, Rz, R9, R10, R14, R14?, R15, R15?, A and B are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds possess utility as tissue-selective androgen receptor modulators (SARM) and are useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.