Patents by Inventor Harriet Palissa

Harriet Palissa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for influencing .beta.-lactam antibiotic production and for isolation of large quantities of ACV synthetase
    Patent number: 5882879
    Abstract: Novel methods and compositions are provided for the enhanced production of .beta.-lactam antibiotics. The process is exemplified by the production of penicillin. In addition, the P. chrysogenum and A. chrysogenum .delta.-(L-.alpha.-aminoadipyl)-L-cysteinyl-D-valine synthetase genes have been isolated and sequenced. Also methods are provided for the production of .delta.-(L-.alpha.-aminoadipyl)-L-cysteinyl-D-valine synthetase using recombined DNA techniques.
    Type: Grant
    Filed: April 4, 1994
    Date of Patent: March 16, 1999
    Assignee: Gist-Brocades, N.V.
    Inventors: Annemarie Veenstra, Juan Francisco Martin, Bruno Diez Garcia, Santiago Gutierez, Jose Luis Barredo, Eduardo Montenegro Prieto, Hans Von Doehren, Harriet Palissa, Henk Van Liempt
  • Oxido reductase enzyme system obtainable from P. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production
    Patent number: 5753435
    Abstract: A new oxido reductase enzyme activity obtainable from P. chrysogenum, involved in the production of .beta.-lactams, the set of genes encoding said enzyme activity, and a method to enhance said production by using the above-mentioned oxido reductase system and other oxido reductase systems or genes encoding for the same are disclosed.
    Type: Grant
    Filed: February 10, 1995
    Date of Patent: May 19, 1998
    Assignee: Gist-Brocades
    Inventors: Yair Aharonowitz, Lucia Helena Maria Van Der Voort, Gerald Cohen, Reolof Ary Lans Bovenberg, Rachel Schreiber, Anat Argaman, Yossef Av-Gay, Helena Maria Nan, Alfred Kattevilder, Harriet Palissa, Henk Van Liempt
  • Oxido reductase enzyme system obtained from P. chrysogenum
    Patent number: 5328839
    Abstract: A new oxido reductase enzyme activity obtainable from P. chrysogenum, involved in the production of .beta.-lactams, the set of genes encoding said enzyme activity, and a method to enhance said production by using the above-mentioned oxido reductase system and other oxido reductase systems or genes encoding for the same have been disclosed.
    Type: Grant
    Filed: March 24, 1992
    Date of Patent: July 12, 1994
    Assignee: Gist-Brocades
    Inventors: Yair Aharonowitz, Lucia H. M. van der Voort, Gerald Cohen, Roelof A. L. Bovenberg, Rachel Schreiber, Anat Argaman, Yossef Av-Gay, Helena M. Nan, Alfred Kattevilder, Harriet Palissa, Henk van Liempt