Patents by Inventor Harriet Ronnholm

Harriet Ronnholm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of neural stem cells and neural progenitor cells
    Patent number: 8318704
    Abstract: The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via S1P or LPA signaling. These methods are useful for reducing at least one symptom of the disorder.
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: November 27, 2012
    Assignee: NeuroNova AB
    Inventors: Per Lindquist, Alex Mercer, Harriet Rönnholm, Lilian Wikström
  • MODULATION OF NEURAL STEM CELLS AND NEURAL PROGENITOR CELLS
    Publication number: 20110189184
    Abstract: The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via S1P or LPA signaling. These methods are useful for reducing at least one symptom of the disorder.
    Type: Application
    Filed: August 31, 2010
    Publication date: August 4, 2011
    Applicant: NeuroNova AB
    Inventors: Per Lindquist, Alex Mercer, Harriet Rönnholm, Lilian Wikström
  • Modulation of neural stem cells and neural progenitor cells
    Patent number: 7811822
    Abstract: The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via S1P or LPA signaling. These methods are useful for reducing at least one symptom of the disorder.
    Type: Grant
    Filed: July 19, 2007
    Date of Patent: October 12, 2010
    Assignee: NeuroNova AB
    Inventors: Per Lindquist, Alex Mercer, Harriet Rönnholm, Lilian Wikström
  • Compounds and methods for increasing neurogenesis
    Publication number: 20090232775
    Abstract: The invention is directed to methods of promoting neurogenesis by contacting neuronal tissue with neurogenesis modulating agents. Novel methods for treating neurological disorders using neurogenesis modulating agents are disclosed.
    Type: Application
    Filed: August 11, 2008
    Publication date: September 17, 2009
    Inventors: Goran Bertilsson, Rikard Erlandsson, Jonas Frisen, Anders Haegerstrand, Jessica Heidrich, Nina Hellstrom, Johan Haggblad, Katarina Jansson, Jarkko Kortesmaa, Per Lindquist, Hanna Lundh, Jacqueline McGuire, Alex Mercer, Karl Nyberg, Amina Ossoinak, Cesare Patrone, Harriet Ronnholm, Lilian Wikstrom, Olof Zachrisson
  • Modulation of neural stem cells and neural progenitor cells
    Publication number: 20080213276
    Abstract: The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via S1P or LPA signaling. These methods are useful for reducing at least one symptom of the disorder.
    Type: Application
    Filed: July 19, 2007
    Publication date: September 4, 2008
    Inventors: Per Lindquist, Alex Mercer, Harriet Ronnholm, Lilian Wikstrom
  • Compositions and methods for culturing stem cells
    Publication number: 20060128014
    Abstract: The present invention provides methods of culturing, propagating, treating, and maintaining stem cells in the presence of a phosphate mimic. In particular, the invention relates to the propagation of stem cells in vitro, the formation of neurospheres in vitro, and to tissue culture of stem cells in the presence of a phosphate mimic. The invention further relates to the treatment of neurodegenerative disorders.
    Type: Application
    Filed: August 26, 2003
    Publication date: June 15, 2006
    Inventors: Johan Haggblad, Carolyn Horrocks, Katarina Jansson, Harriet Ronnholm
  • Compounds and methods for increasing neurogenesis
    Publication number: 20060079448
    Abstract: The invention is directed to methods of promoting neurogenesis by contacting neuronal tissue with neurogenesis modulating agents. Novel methods for treating neurological disorders using neurogenesis modulating agents are disclosed.
    Type: Application
    Filed: November 28, 2005
    Publication date: April 13, 2006
    Inventors: Goran Bertilsson, Rikard Erlandsson, Jonas Frisen, Anders Haegerstrand, Jessica Heidrich, Nina Hellstrom, Johan Haggblad, Katarina Jansson, Jarkko Kortesmaa, Per Lindquist, Hanna Lundh, Jacqueline McGuire, Alex Mercer, Karl Nyberg, Amina Ossoinak, Cesare Patrone, Harriet Ronnholm, Lilian Wikstrom, Olof Zachrisson
  • Compounds and methods for increasing neurogenesis
    Patent number: 6969702
    Abstract: The invention is directed to methods of promoting neurogenesis by contacting neuronal tissue with neurogenesis increasing agents. Novel methods for treating neurological disorders using neurogenesis increasing agents are disclosed.
    Type: Grant
    Filed: May 19, 2004
    Date of Patent: November 29, 2005
    Assignee: NeuroNova AB
    Inventors: Göran Bertilsson, Rikard Erlandsson, Jonas Frisen, Anders Haegerstrand, Jessica Heidrich, Nina Hellström, Johan Häggblad, Katarina Jansson, Jarkko Kortesmaa, Per Lindquist, Hanna Lundh, Jacqueline McGuire, Alex Mercer, Karl Nyberg, Amina Ossoinak, Cesare Patrone, Harriet Rönnholm, Lilian Wikström, Olof Zachrisson
  • Compounds and methods for increasing neurogenesis
    Publication number: 20050209142
    Abstract: The invention is directed to methods of promoting neurogenesis by contacting neuronal tissue with neurogenesis modulating agents. Novel methods for treating neurological disorders using neurogenesis modulating agents are disclosed.
    Type: Application
    Filed: November 19, 2004
    Publication date: September 22, 2005
    Inventors: Goran Bertilsson, Rikard Erlandsson, Jonas Frisen, Anders Haegerstrand, Jessica Heidrich, Nina Hellstrom, Johan Haggblad, Katarina Jansson, Jarkko Kortesmaa, Per Lindquist, Hanna Lundh, Jacqueline McGuire, Alex Mercer, Karl Nyberg, Amina Ossoinak, Cesare Patrone, Harriet Ronnholm, Lilian Wikstrom, Olof Zachrisson
  • Compounds and methods for increasing neurogenesis
    Publication number: 20050009742
    Abstract: The invention is directed to methods of promoting neurogenesis by contacting neuronal tissue with neurogenesis modulating agents. Novel methods for treating neurological disorders using neurogenesis modulating agents are disclosed.
    Type: Application
    Filed: May 19, 2004
    Publication date: January 13, 2005
    Inventors: Goran Bertilsson, Rikard Erlandsson, Jonas Frisen, Anders Haegerstrand, Jessica Heidrich, Nina Hellstrom, Johan Haggblad, Katarina Jansson, Jarkko Kortesmaa, Per Lindquist, Hanna Lundh, Jacqueline McGuire, Alex Mercer, Karl Nyberg, Amina Ossoinak, Cesare Patrone, Harriet Ronnholm, Lilian Wikstrom, Olof Zachrisson
  • Compounds and methods for increasing neurogenesis
    Publication number: 20050009847
    Abstract: The invention is directed to methods of promoting neurogenesis by contacting neuronal tissue with intracellular cAMP elevating agents and intracellular Ca2+ elevating agents. Novel agents for promoting neurogenesis are disclosed. These agents include novel agents for increasing intracellular cAMP.
    Type: Application
    Filed: November 20, 2003
    Publication date: January 13, 2005
    Inventors: Goran Bertilsson, Rikard Erlandsson, Jonas Frisen, Anders Haegerstrand, Jessica Heidrich, Nina Hellstrom, Johan Haggblad, Katarina Jansson, Jarkko Kortesmaa, Per Lindquist, Hanna Lundh, Jacqueline McGuire, Alex Mercer, Karl Nyberg, Amina Ossoinak, Cesare Patrone, Harriet Ronnholm, Lilian Wikstrom, Olof Zachrisson
  • Therapeutic use of selective LXR modulators
    Publication number: 20050003998
    Abstract: The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via LXR signaling. These methods are useful for reducing at least one symptom of the disorder.
    Type: Application
    Filed: August 15, 2003
    Publication date: January 6, 2005
    Inventors: Goran Bertilsson, Jessica Heidrich, Johan Haggblad, Harriet Ronnholm, Olof Zachrisson
  • Functional role and potential therapeutic use of PACAP, VIP and Maxadilan in relation to adult neural stem or progenitor cells
    Publication number: 20040038888
    Abstract: The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via PACAP, Maxadilan or VIP signaling. These methods are useful for reducing at least one symptom of the disorder.
    Type: Application
    Filed: May 2, 2003
    Publication date: February 26, 2004
    Inventors: Alex Mercer, Cesare Patrone, Harriet Ronnholm, Lilian Wikstrom
  • Modulation of neural stem cells and neural progenitor cells
    Publication number: 20040014662
    Abstract: The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via S1P or LPA signaling. These methods are useful for reducing at least one symptom of the disorder.
    Type: Application
    Filed: May 8, 2003
    Publication date: January 22, 2004
    Inventors: Per Lindquist, Alex Mercer, Harriet Ronnholm, Lilian Wikstrom
  • Functional role and potential therapeutic use of Reelin, Gas6 and Protein S in relation to adult neural stem or progenitor cells
    Publication number: 20030165485
    Abstract: The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via Reelin, Gas6 or Protein S signaling. These methods are useful for reducing at least one symptom of the disorder.
    Type: Application
    Filed: November 8, 2002
    Publication date: September 4, 2003
    Inventors: Goran Bertilsson, Anna Falk, Jonas Frisen, Jessica Heidrich, Kristina Hellstrom, Jarkko Kortesmaa, Per Lindquist, Hanna Lundh, Jacqueline McGuire, Alex Mercer, Cesare Patrone, Harriet Ronnholm, Lilian Wikstrom, Olof Zachrisson
  • Method for preparing a model system for cellular insulin resistance and device for use with the model system
    Publication number: 20010021499
    Abstract: A method of preparing a cellular in vitro model system for insulin resistance by inducing insulin resistance to an animal cell culture in a cell culture medium comprises incubating the cell culture in the presence of glucose and at least one fatty acid, preferably a long-chain fatty acid, wherein the concentration of glucose is in the range of about 5 to about 25 mM and the concentration of fatty acid is less than about 2 mM. A device that may be used in the method comprises a cell culture flask (1), and a support member (2) for a carbon dioxide absorbent body, which support member (2) is partially insertable into the culture flask (1) and fixable in the flask opening with the absorbent body extending into the flask.
    Type: Application
    Filed: January 2, 2001
    Publication date: September 13, 2001
    Inventors: Antek Wielburski, Harriet Ronnholm