Patents by Inventor Harriet Wall Hamilton

Harriet Wall Hamilton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxindole substituted piperazine derivatives
    Publication number: 20040142933
    Abstract: This invention relates to compounds of the formula I 1
    Type: Application
    Filed: October 28, 2003
    Publication date: July 22, 2004
    Inventors: George William Forrest, Harriet Wall Hamilton
  • 3-Sulfenylation of indole-2-carboxylates
    Publication number: 20040133014
    Abstract: A highly efficient one-pot procedure for 3-sulfenilation of indole 2-carboxylates is described. Treatment of thiols with N-chlorosuccinimide at −78° C. in CH2Cl2 affords sulfenyl chlorides in situ that readily react with indole 2-carboxylates to give 3-thioindoles in high yields. This new method is milder, produces less waste, and is compatible with a wide range of thiol and indole functionality.
    Type: Application
    Filed: July 31, 2003
    Publication date: July 8, 2004
    Inventors: Harriet Wall Hamilton, Alexei P. Krasutsky, Jessica Reed, Kevin Schlosser
  • Diazepinones as antiviral agents
    Publication number: 20040116410
    Abstract: The invention is novel compounds of formula (I) which exhibit an improved therapeutic index and improved metabolic stability which are useful in the treatment and/or prevention of herpes viral infections. Novel intermediates useful in the synthesis of the final compounds are also part of the invention.
    Type: Application
    Filed: February 18, 2003
    Publication date: June 17, 2004
    Inventors: Hidetsura Cho, Rocco Dean Gogliotti, Harriet Wall Hamilton, Alexei Krasutsky, Takeshi Nakamura, Hiroki Tada, Peter Craig Weber
  • Peptidyl calcium channel blockers
    Patent number: 6423689
    Abstract: The present invention provides compounds that block calcium channels having the Formula I shown below. The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, or epilepsy and to pharmaceutical compositions that contain the compounds of Formula I.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: July 23, 2002
    Assignees: Warner-Lambert Company, Neurex Corporation
    Inventors: Richard John Booth, Louis Brogley, Wayne Livingston Cody, David Thomas Connor, Harriet Wall Hamilton, John Xiaoqiang He, Lain-Yen Hu, Leonard Joseph Lescosky, Thomas Charles Malone, Laszlo Nadasdi, Michael Francis Rafferty, Bruce David Roth, Diego F. Silva, Yuntao Song, Balazs G. Szoke, Laszlo Urge
  • Dihydropyrones with improved antiviral activity
    Patent number: 6046355
    Abstract: This invention pertains to improved antiviral activity of 6,6-disubstituted-5,6-dihydropyran-2-ones caused by judicious placement of certain polar substituents at the 3 and/or 6 positions.The same substituents which enhance the cellular activity also diminish cytotoxicity further enhancing the desirable properties of these agents as antivirals.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: April 4, 2000
    Assignee: Warner-Lambert Company
    Inventors: Frederick Earl Boyer, Jr., John Michael Domagala, Edmund Lee Ellsworth, Christopher Andrew Gajda, Susan Elizabeth Hagen, Harriet Wall Hamilton, Elizabeth Ann Lunney, Larry James Markoski, Josyula Venkata Nagendra Vara Prasad, Bradley Dean Tait
  • Dihydropyrones with improved antiviral activity
    Patent number: 5834506
    Abstract: This invention pertains to improved antiviral activity of 6,6-disubstituted-5,6-dihydropyran-2-ones caused by judicious placement of certain polar substituents at the 3 and/or 6 positions.The same substituents which enhance the cellular activity also diminish cytotoxicity further enhancing the desirable properties of these agents as antivirals.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: November 10, 1998
    Assignee: Warner-Lambert Company
    Inventors: Frederick Earl Boyer, Jr., John Michael Domagala, Edmund Lee Ellsworth, Christopher Andrew Gajda, Susan Elizabeth Hagen, Harriet Wall Hamilton, Elizabeth Ann Lunney, Larry James Markoski, Josyula Venkata Nagendra Vara Prasad, Bradley Dean Tait
  • Amino-substituted heterocycles as renin inhibitors
    Patent number: 5643879
    Abstract: The invention concerns novel renin-inhibitory compounds which contain an amino-substituted heterocycle at the P.sub.2 position. These are useful for treating renin-associated hypertension, congestive heart failure, glaucoma, hyperaldosteronism, and diseases caused by retroviruses including HTLV-I and -III. Processes for preparing the compounds, compositions containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension, or hyperaldosteronism.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: July 1, 1997
    Assignee: Warner-Lambert Company
    Inventors: Cleo Connolly, Annette Marion Doherty, Harriet Wall Hamilton, William Chester Patt, Ila Sircar