Patents by Inventor Harris Nusbaum

Harris Nusbaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of templates for methylation analysis
    Patent number: 11827927
    Abstract: The invention relates to a method of preparing and using a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a method of preparing and analysing a library of template polynucleotides suitable for methylation analysis.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: November 28, 2023
    Assignees: ILLUMINA CAMBRIDGE LIMITED, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Niall Gormley, Andreas Gnirke, David Jaffe, Harris Nusbaum
  • PREPARATION OF TEMPLATES FOR METHYLATION ANALYSIS
    Publication number: 20210277459
    Abstract: The invention relates to a method of preparing and using a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a method of preparing and analysing a library of template polynucleotides suitable for methylation analysis.
    Type: Application
    Filed: February 17, 2021
    Publication date: September 9, 2021
    Inventors: Niall Gormley, Andreas Gnirke, David Jaffe, Harris Nusbaum
  • Preparation of templates for methylation analysis
    Patent number: 10954554
    Abstract: The invention relates to a kit for preparing a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a kit for preparing a library of template polynucleotides suitable for methylation analysis.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: March 23, 2021
    Assignees: Massachusetts Institute of Technology
    Inventors: Niall Gormley, Andreas Gnirke, David Jaffe, Harris Nusbaum
  • Identification of biomolecular interactions
    Patent number: 10655162
    Abstract: The present disclosure, in some aspects, provides compositions, systems and methods for proximity-based detection of target biomolecules of interest.
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: May 19, 2020
    Assignee: The Broad Institute, Inc.
    Inventors: Alon Goren, Robert Nicol, Harris Nusbaum
  • PREPARATION OF TEMPLATES FOR METHYLATION ANALYSIS
    Publication number: 20180237844
    Abstract: The invention relates to a kit for preparing a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a kit for preparing a library of template polynucleotides suitable for methylation analysis.
    Type: Application
    Filed: January 10, 2018
    Publication date: August 23, 2018
    Inventors: Niall Gormley, Andreas Gnirke, David Jaffe, Harris Nusbaum
  • Preparation of templates for methylation analysis
    Patent number: 9868982
    Abstract: The invention relates to a method of preparing and using a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a method of preparing and analyzing a library of template polynucleotides suitable for methylation analysis.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: January 16, 2018
    Assignees: ILLUMINA CAMBRIDGE LIMITED, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Niall Gormley, Andreas Gnirke, David Jaffe, Harris Nusbaum
  • Preparation of templates for methylation analysis
    Publication number: 20090148842
    Abstract: The invention relates to a method of preparing and using a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a method of preparing and analysing a library of template polynucleotides suitable for methylation analysis.
    Type: Application
    Filed: February 7, 2008
    Publication date: June 11, 2009
    Inventors: Niall Gormley, Andreas Gnirke, David Jaffe, Harris Nusbaum