Patents by Inventor Harry A. Albrecht

Harry A. Albrecht has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030059577
    Abstract: A multi-layer ceramic matrix composite structure (40) having a plurality of fiber-reinforced cooling passages (42) formed therein. The cooling passages are formed by the removal of a fugitive material (24). The fugitive material is part of a wrapped fugitive material structure (28) containing a layer of reinforcing ceramic fibers (26) that is used to lay-up the multi-layer structure. An intermediate layer of ceramic fabric 56 may be placed alternately over and under the wrapped fugitive material structure to separate the cooling passages into alternating upper (54) and lower (52) cooling passages. The transversely oriented fibers surrounding the cooling passages serve to increase the interlaminar strength of the structure when compared to prior art designs. An airfoil member (112) incorporating such reinforced integral cooling passages (120) is provided.
    Type: Application
    Filed: September 24, 2001
    Publication date: March 27, 2003
    Applicant: Siemens Westinghouse Power Corporation
    Inventors: Jay Morrison, Steven C. Butner, Christian X. Campbell, Harry A. Albrecht, Yevgeuiy Shteyman
  • Patent number: 5590857
    Abstract: Apparatus for operating railroad switches, including operation in the trailing mode, and a switch machine having a throw bar and throw rod for enabling the throwing of switch points into selected positions so as to control the switching of rolling stock. A trailing device, including a trailing rod portion of the throw rod, is coupled to the throw bar, said device including an arrangement responsive to a wrong direction load impressed on said switch points so as to move said throw rod, for enabling non-damaging movement of said throw rod.
    Type: Grant
    Filed: August 19, 1994
    Date of Patent: January 7, 1997
    Assignee: General Railway Signal Corporation
    Inventors: Harry A. Albrecht, Daniel W. Van Alstine
  • Patent number: 5336768
    Abstract: There are presented antibacterial cephalosporine having broad antimicrobial activity, having the formula ##STR1## wherein R is hydrogen or a carboxylic acid-protecting group: R.sub.1 represents a substituted piperazinyl group of formula ##STR2## or a substituted pyrrolidinylamino group of formula ##STR3## or a substituted pyrrolidinylmethylamino group of formula ##STR4## where the piperazinyl or pyrrolidinyl group may be optionally substituted with one or more lower alkyl groups, and where Q represents a substituted quinolinyl or naphthyridinyl group: R.sub.2 is selected from the group consisting of hydrogen, lower alkoxy, lower alkylthio and amido; R.sub.3 is hydrogen or an acyl group: and m is 0, 1 or 2, but preferably 0; as well as the corresponding readily hydrolyzable esters. pharmaceutically acceptable salts and hydrates of these compounds.
    Type: Grant
    Filed: May 24, 1988
    Date of Patent: August 9, 1994
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Harry A. Albrecht, Dennis D. Keith, Frederick M. Konzelmann, Pamela L. Rossman, Manfred Weigele
  • Patent number: 5329002
    Abstract: There are presented antibacterial cephalosporins having broad antimicrobial activity as well as intermediates for their formation, such compounds having the formula ##STR1## wherein R is hydrogen or a carboxylic acid-protecting group; R.sub.1 is a substituted piperazinium group of the formula ##STR2## in which Q represents a substituted quinolinyl or naphthyridinyl group and the piperazine nucleus may be optionally substituted with one or more lower alkyl groups; R.sub.2 is selected from the group consisting of hydrogen, lower alkoxy, lower alkylthio and amido; R.sub.3 is hydrogen or an acyl group; and m is 0, 1 or 2, preferably 0;as well as the corresponding readily hydrolyzable esters, pharmaceutically acceptable salts and hydrates of these compounds.
    Type: Grant
    Filed: July 6, 1990
    Date of Patent: July 12, 1994
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Harry A. Albrecht, Dennis D. Keith, Chung-Chen Wei, Manfred Weigele, Roxana Yang
  • Patent number: 5147871
    Abstract: There are presented anti-bacterial cephalosporins having broad antimicrobial activity of the formula ##STR1## wherein R.sub.1 is an antibiotically active quinolonyl; R.sub.2 is selected from the group consisting of hydrogen, lower alkoxy, amino, lower alkylthio and amido; R.sub.3 is selected from the group consisting of hydrogen, and acyl group, and m is 0, 1 or 2 and the readily hydrolysable esters or salts of these compounds and hydrates of the compounds of formula I or of their esters or salts.
    Type: Grant
    Filed: December 5, 1991
    Date of Patent: September 15, 1992
    Assignee: Hoffmann La-Roche, Inc.
    Inventors: Harry A. Albrecht, Ka-Kong Chan, Dennis D. Keith, Rudolf L. Then, Manfred Weigele
  • Patent number: 4912214
    Abstract: Compounds of the formula ##STR1## wherein A is ##STR2## in which R.sub.1 is acyl, R.sub.2 is hydrogen, lower alkyl, lower alkoxy-carbonyl or aminocarbonyl, R.sub.3 is hydrogen or lower alkyl, R.sub.4 and R.sub.4, are each hydrogen, lower alkyl, lower alkoxy, aryl, aryloxy or aralkyl, as well as the pharmaceutically acceptable salts of such compounds, are useful as antibacterial agents for combatting infections in mammals.
    Type: Grant
    Filed: July 11, 1989
    Date of Patent: March 27, 1990
    Assignee: Hoffman-La Roche Inc.
    Inventors: Harry A. Albrecht, Dennis D. Keith, Frederick M. Konzelman
  • Patent number: 4831130
    Abstract: Compounds of the formula ##STR1## wherein A is one of the following: ##STR2## in which R.sub.1, is acyl, R.sub.2 is hydrogen, lower alkyl, lower alkoxycarbonyl or aminocarbonyl, R.sub.3 is hydrogen or lower alkyl and R.sub.4 and R.sub.4 ' are hydrogen, lower alkyl, lower alkoxy, acyl or aralkyl, as well as pharmaceutically acceptable salts of such compounds, are useful as antibacterial agents.
    Type: Grant
    Filed: July 10, 1987
    Date of Patent: May 16, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Harry A. Albrecht, Frederick M. Konzelmann, Dennis D. Keith
  • Patent number: 4584132
    Abstract: A novel family of .beta.-lactam antibacterials, synthetic methods and intermediates useful in the production of such antibacterials, and the use of such compounds as antibacterials are disclosed. The novel compounds have the formula ##STR1## wherein, Z.sup.1 is a group --OR.sup.1, --NR.sup.3 R.sup.4, or --SR.sup.5 ;Z.sup.2 is a group --OR.sup.2, --NR.sup.3 R.sup.4, or --SR.sup.6 ;R.sup.1 and R.sup.2 may be either the same or different and each is H, lower alkyl, aralkyl, aryl or heteroaryl;R.sup.3 and R.sup.4 may be either the same or different and each is H, lower alkyl, aralkyl, aryl or heteroaryl;R.sup.5 and R.sup.6 may be either the same of different and each is H, lower alkyl, aralkyl, aryl or heteroaryl;R.sup.7 is H, lower alkyl, or lower alkoxycarbonyl; and,R.sup.8 is acyl;as well as pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: August 9, 1983
    Date of Patent: April 22, 1986
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Harry A. Albrecht, Frederick M. Konzelmann, Dennis D. Keith
  • Patent number: 3949550
    Abstract: The engine exhaust flow diverter is formed as a duct, extending from the exhaust section of a gas turbine powerplant, having a closed end which is contoured externally as a nozzle plug. First exit means for the flow from the powerplant extends around the duct just forwardly of the contoured plug and second exit means for the flow extends around the duct midway between the first exit means and the end of the exhaust section of the powerplant. An annular door is axially movable around the duct between an open and closed position to control the flow through the second exit opening and an annular shroud is axially movable around the duct between an open and closed position to control the flow through the second exit means. The annular shroud cooperates with the contoured nozzle plug to form a conventional nozzle. An actuating system is connected to both the annular door and annular shroud to actuate them so that when one is open the other is closed.
    Type: Grant
    Filed: March 5, 1975
    Date of Patent: April 13, 1976
    Assignee: United Technologies Corporation
    Inventors: Harry A. Albrecht, Michael Diver, Norman F. Fowle, Edwin E. Knight